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16 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  8-cyclopentyl-1,3-dipropylxanthine -  -  [2] 215, 299 💬
 2  Artesunate [1] Artesunate;  [1] D02482 💬  -  [7] 46, 53, 66, 96, 97, 215, 271 💬
 3  Calcium [34] Amorphous calcium carbonate; Ascal(r) / carbasalate calcium; Atorvastatin calcium; Calcitriol & calcium; Calcium; Calcium and cholecalciferol; Calcium and vitamin d combination; Calcium carbonate; Calcium carbonate and alphacalcidol; Calcium carbonate d; Calcium channel blockers; Calcium citrate; Calcium citrate with vitamin d2; Calcium gluconate; Calcium lactate; Calcium levofolinate; Calcium rosuvastatin; Calcium, dietary; Carbasalate calcium; Crestor tablets (calcium rosuvastatin) film-coated tablets; Crystalline calcium supplements; Ethylhydrogenfumarat, calciumsalz; Ibandronate+alfacalcidol+calcium; Low molecular weight heparin calcium injection; Other: calcium stable isotope; Other: determination of calcium intake by a dietician interview; Other: empiric use of calcium carbonate and calcitriol; Other: pth based calcium carbonate and calcitriol repletion; Other: serum calcium concentrations results; Rosuvastatin calcium; Rosuvastatin calcium 40mg; Symptomatic treatment (converting enzyme inhibitor, angiotensin ii, anti-renin, aldosterone antagonist diuretic, beta blocker, calcium inhibitor, statin); Vidofludimus calcium; Vidofludimus calcium dihydrate;  -  -  [27]  6 , 13, 19, 46, 49, 51, 53, 56, 68, 75, 79, 84, 93, 94, 95, 96, 97, 186, 214, 215, 222, 224, 235, 265, 274, 298, 299 💬
 4  Calcium gluconate [1] Calcium gluconate;  [1] D00935 💬  -  [3] 214, 215, 235 💬
 5  Dexmedetomidine [10] Dexmedetomidine; Dexmedetomidine 1; Dexmedetomidine 2; Dexmedetomidine 3; Dexmedetomidine group; Dexmedetomidine hydrochloride; Dexmedetomidine hydrochloride infusion; Dexmedetomidine with ropivacaine; Fentanyl (low dose) + dexmedetomidine; Scopolamine, atropine, edaravone and dexmedetomidine;  [2] D00514
D01205 💬
[3] ADRA2A, ADRA2B, ADRA2C 💬 [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [12]  2 ,  4 ,  6 , 21, 34, 46, 70, 113, 212, 215, 226, 280 💬
 6  Dobutamine [2] Dobutamine; Other: dobutamine;  [4] D00632
D03879
D03880
D03881 💬
[1] ADRB1 💬 [10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway  [3] 57, 58, 215 💬
 7  Eplerenone [1] Eplerenone;  [1] D01115 💬 [1] NR3C2 💬 [1] Aldosterone-regulated sodium reabsorption  [4] 75, 113, 210, 215 💬
 8  Fentanyl [8] Fentanyl; Fentanyl (high dose); Fentanyl (low dose); Fentanyl (low dose) + dexmedetomidine; Fentanyl transdermal patch; Multi-modal pain management [fentanyl]; Standard analgesia use [fentanyl]; Transdermal fentanyl matrix, gabapentin;  [2] D00320
D01399 💬
[1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [4] 46, 70, 215, 231 💬
 9  Flunarizine [2] D01303
D07971 💬
[3] CACNA1G, CACNA1H, CACNA1I 💬 [8] Aldosterone synthesis and secretion, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GnRH secretion, MAPK signaling pathway, Type II diabetes mellitus  [4] 58, 86, 149, 215 💬
 10  Ketamine [6] Esketamine; Esketamine hydrochloride; Ketamine; Multi-modal pain management [intravenous ketamine]; S-ketamine; S-ketamine & midazolam;  [2] D00711
D08098 💬
[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬 [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [8]  2 ,  4 ,  6 , 13, 70, 113, 156, 215 💬
 11  Losartan [12] Lisinopril, losartan, and atorvastatin; Losartan; Losartan and atenolol or propranolol; Losartan and nebivolol; Losartan and other angiotensin receptor blockers; Losartan bluefish 50 mg; Losartan hexal; Losartan potasico; Losartan potassium; Losartan tablets & qingremoshen granule; Other: losartan; Sildenafil and losartan;  [2] D00357
D08146 💬
[1] AGTR1 💬 [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [18] 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
 12  Phenoxymethylpenicillin [3] D00497
D02506
D05411 💬
 -  [3] 13, 97, 215 💬
 13  Potassium [5] Dipotassium salt; Losartan potassium; Potassium; Potassium sparing diuretic; Potassium supplement;  [1] D08403 💬  -  [10] 36, 46, 66, 67, 98, 115, 167, 179, 215, 235 💬
 14  Sodium citrate [1] Sodium citrate;  [2] D01781
D05855 💬
 -  [4] 67, 214, 215, 235 💬
 15  Tranexamic acid [3] Tranexamic acid; Tranexamic acid 100 mg/ml; Tranexamic acid injection [cyklokapron];  [1] D01136 💬 [1] PLG 💬 [4] Complement and coagulation cascades, Influenza A, Neuroactive ligand-receptor interaction, Staphylococcus aureus infection  [5] 46, 70, 215, 227, 288 💬
 16  Ubidecarenone [1] D01065 💬  -  [13]  2 ,  5 ,  6 ,  8 , 10, 18, 46, 57, 86, 113, 193, 214, 215 💬