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7 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  Acetylcysteine [12] Acetylcysteine; Acetylcysteine effervescent tablets; Acetylcysteine sodium; Fluimucil (acetylcysteine); Glatiramer acetate, n-acetylcysteine; Jaktinib dihydrochloride monohydrate 50mg bid and mimic tablets of jakitinib hydrochloride 75mg bid and acetylcysteine effervescent tablets; Jaktinib dihydrochloride monohydrate 75mg bid and mimic tablets of jakitinib hydrochloride 50mg bid and acetylcysteine effervescent tablets; N acetylcysteine; N-acetylcysteine; N-acetylcysteine (nac); N-acetylcysteine capsule; N-acetylcysteine, (nac);  [1] D00221 💬  -  [17]  6 , 13, 19, 20, 34, 49, 51, 58, 85, 90, 94, 111, 164, 193, 233, 298, 299 💬
 2  Dantrolene [2] Dantrolene; Dantrolene sodium;  [2] D02274
D02347 💬
 -  [2] 13, 233 💬
 3  Deferiprone [11] Deferiprone; Deferiprone (ferriprox); Deferiprone 20mg; Deferiprone 30mg; Deferiprone 600 mg delayed release tablet; Deferiprone 80 mg/ml oral solution; Deferiprone 80 mg/ml oral solution (ferriprox); Deferiprone dr; Deferiprone oral solution; Deferiprone treated; Ferrprox (deferiprone);  [1] D07416 💬  -  [6]  2 ,  6 , 18, 120, 122, 233 💬
 4  Exenatide [5] Exenatide; Exenatide 10 micrograms; Exenatide 5 micrograms; Exenatide extended release 2mg (bydureon); Exenatide pen injector [bydureon];  [1] D04121 💬 [1] GLP1R 💬 [3] Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [4]  6 , 17, 193, 233 💬
 5  Metformin [21] 750 mg metformin and 7.5 g l-citrulline daily p.o.; Glucophage (metformin); L-citrulline and metformin & l-citrulline; Metformin; Metformin (generic); Metformin 500mg; Metformin and metformin & l-citrulline; Metformin hcl; Metformin hydrochloride; Metformin treatment; Metformin/cp-690,550; Metformina; Metformina - 500 30 compresse 500 mg; Metformine; Metformine arrow 500mg; Metformine hcl 500 pch; Metformine sandoz 850 mg filmomhulde tabletten; Other: metformin; Pioglitazone or metformin; Sitagliptin and metformin; [metformina];  [2] D00944
D04966 💬
[2] PRKAA1, PRKAA2 💬 [19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway  [21]  2 ,  6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬
 6  Sitagliptin [2] Sitagliptin; Sitagliptin and metformin;  [1] D08516 💬 [1] DPP4 💬 [1] Protein digestion and absorption  [4]  6 , 75, 233, 299 💬
 7  Valproic acid [3] Valproic acid; Valproic acid (vpa); Valproic acid and levocarnitine;  [1] D00399 💬 [7] ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬 [17] Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism  [16]  2 ,  3 ,  5 ,  6 , 13, 26, 34, 65, 85, 89, 90, 102, 222, 233, 256, 331 💬