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6 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes
Disease ID
 1  Gold [7] Gold; Gold nanocrystals; Mtx goldshield tablets; Other: comparator: cpet cycle ergometer (gold standard); Procedure: quantiferon-tb gold assay; Procedure: repair of cdh w/sis gold; Sodium aurothiomalate (intramuscular gold);  -  -  [38]  2 ,  5 ,  6 , 13, 17, 34, 46, 49, 50, 53, 65, 68, 76, 84, 86, 91, 93, 95, 96, 97, 98, 113, 158, 162, 171, 218, 222, 224, 227, 230, 271, 291, 294, 296, 298, 299, 310, 318 💬
 2  Milrinone [1] Milrinone;  [2] D00417
D02085 💬
[2] PDE3A, PDE3B 💬 [11] Apelin signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 294 💬
 3  Nitric Oxide [14] Inhaled nitric oxide; Inhaled nitric oxide & inopulse delivery; Inhaled nitric oxide - 30 mcg/kg ibw/hr; Inhaled nitric oxide 5,10,15 mcg/kg ibw/hr; Inhaled nitric oxide 75 mcg/kg ibw/hr; Nitric oxide; Nitric oxide 160 ppm; Nitric oxide for inhalation; Nitric oxide generated by the geno nitrosyl delivery system; Nitric oxide plus oxygen; Nitric oxide supplement; Other: oral nitric oxide testing; Procedure: exhaled nitric oxide; Procedure: exhaled nitric oxide assessment;  [1] D00074 💬  -  [8] 46, 85, 86, 98, 210, 251, 294, 299 💬
 4  Omeprazole [19] Bms drug-drug interaction cocktail (montelukast, flurbiprofen, omeprazole, midazolam, and digoxin); Clartihromycin, amoxicillin, and omeprazole; Diclofenac + omeprazole; Dimebon + omeprazole; Esomeprazole; Esomeprazole 20 mg; Naproxen 500 mg tablets (pn 200 minus omeprazole); Nexium (esomeprazole magnesium); Omeprazole; Omeprazole (uk licensed generic product); Omeprazole 20 mg; Omeprazole 20mg; Omeprazole 20mg bid; Omeprazole 40 mg; Omeprazole 40mg capsule; Omeprazole magnesium; Omeprazole rectally 1mg/kg; Pn 200 tablets (500 mg naproxen and 20 mg omeprazole); Rifaximin+omeprazole+miralax;  [4] D00455
D01207
D05259
D05261 💬
[2] ATP4A, ATP4B 💬 [4] Collecting duct acid secretion, Gastric acid secretion, Metabolic pathways, Oxidative phosphorylation  [16]  6 ,  8 , 13, 21, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬
 5  Oxygen [39] Behavioral: respiratory and exercise therapy with supplemental oxygen; Combination product: hyperbaric oxygen therapy-; Continuous oxygen; Device: auto-titrating oxygen system; Device: capacity of muscular oxygen extraction; Device: high flow nasal oxygen cannula; Device: hyperbaric oxygen; Device: intermittent exposure to oxygen via oro-nasal mask; Device: nocturnal oxygen , nocturnal bi-level positive pressure ventilation; Device: oxygen; Device: oxygen saturation; Device: standard oxygen therapy/ra; Diagnostic test: maximum oxygen uptake; Helium / oxygen mixed gas inhalation therapy; Medical air vs oxygen; Medical grade oxygen; Nitric oxide plus oxygen; Other: 60% oxygen; Other: air - oxygen; Other: hyperbaric oxygen; Other: hyperbaric oxygen therapy; Other: muscle oxygenation; Other: optional blood-oxygen-level dependent functionalmri; Other: oxygen; Other: oxygen (2liter/min); Other: oxygen (4liter/min); Other: oxygen - air; Other: oxygen supplementation; Oxygen; Oxygen 40 %; Oxygen supplementation; Oxygen, liquid; Perfluorinated gas/oxygen mixture; Procedure: hyperbaric oxygen; Procedure: hyperbaric oxygen therapy; Procedure: long term oxygen therapy; Procedure: oxygen flow at the optic nerve head measurement; Procedure: supplemental oxygen via a mask; Standard analgesia use [oxygen];  [1] D00003 💬  -  [18]  6 , 13, 19, 46, 49, 70, 84, 85, 86, 88, 90, 96, 97, 193, 226, 294, 299, 330 💬
 6  Sildenafil [32] 20 mg sildenafil citrate by mouth; 5% sildenafil cream; Access program - sildenafil citrate, viagra, revatio; Bosentan and sildenafil; Duo-therapy with sildenafil + bosentan; Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan); G04be03- sildenafil - sildenafil (citrato); Mono-therapy with sildenafil; Oral sildenafil; Other: standard of care sildenafil; Sildenafil; Sildenafil (50 mg); Sildenafil (acute-1 hour); Sildenafil (as citrate); Sildenafil (revatio); Sildenafil (revatio) 20 mg tid; Sildenafil (subchronic-4 weeks); Sildenafil 20 mg tablets; Sildenafil 20mg; Sildenafil 20mg and bosentan 62.5mg; Sildenafil 40mg oral capsule; Sildenafil and losartan; Sildenafil by injection; Sildenafil citrate; Sildenafil citrate (uk-92,480); Sildenafil filmtabletten; Sildenafil singly or in association with bosentan; Sildenafil therapy; Sildenafilo; Sitaxsentan and sildenafil; Sodium tanshinone iia sulfonate diluted with 5% glucose solution,20mg sildenafil citrate by mouth; Tadalafil and sildenafil;  [2] D02229
D08514 💬
[1] PDE5A 💬 [3] Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway  [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬