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e.g. Sirolimus, Adalimumab

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4 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  Bosentan [18] Bosentan; Bosentan (tracleer); Bosentan 125 mg; Bosentan 62.5 mg; Bosentan administration; Bosentan and sildenafil; Bosentan group; Bosentan monohidrato; Bosentan monohydrat; Bosentan monohydrate; Bosentan mylan; Bosentan, ambrisentan; Device: nirs after bosentan administration; Device: tcd after bosentan administration; Duo-therapy with sildenafil + bosentan; Era and pde-5i (sildenafil, tadalafil, bosentan, macitentan); Sildenafil 20mg and bosentan 62.5mg; Sildenafil singly or in association with bosentan;  [2] D01227
D07538 💬		 [2] EDNRA, EDNRB 💬 [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [11] 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
 2  Erythropoietin [4] Erythropoietin; Erythropoietin human recombinant (eporh); Recombinant human erythropoietin; Recombinant human erythropoietin(rhepo);  [1] D03231 💬 [1] EPOR 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [10]  2 ,  6 , 13, 18, 22, 46, 47, 70, 95, 96 💬
 3  Filgrastim [7] Ep2006 (filgrastim); Filgrastim; Filgrastim (g-csf); Filgrastim hexal; Filgrastim, alemtuzumab; Granulocyte colony-stimulating factor (filgrastim); Pegfilgrastim;  [1] D03235 💬 [1] CSF3R 💬 [5] Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway, PI3K-Akt signaling pathway, Pathways in cancer  [33]  2 ,  6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬
 4  Thrombopoietin [5] Combination of thrombopoietin mimetic and cyclosporin a; Recombinant human thrombopoietin; Recombinant human thrombopoietin (rh-tpo); Recombinant human thrombopoietin (rhtpo); Thrombopoietin;  -  -  -  [3] 47, 60, 63 💬