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45 / 2,001 drugs

No. DrugBank Drug (Description in trials) KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  Acetate [98] 11c-acetate; 2-(2-(2-amino-9h-purin-9-yl)ethyl)-1,3-propanediol diacetate ester; 20mg/0.5ml glatiramer acetate; 40 mg glatiramer acetate; 90 mg hydrocortisone acetate suppository with sephure suppository applicator; Abiraterone acetate; Acetate; Bazedoxifene acetate; Betamethasone sodium phosphate/betamethasone acetate (celestone® soluspan®), 30 mg im once a day for four days; Caspofungin acetate; Combination product: twice daily 90 mg hydrocortisone acetate suppository administered with sephure applicator; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cortisone acetate; Cosyntropin acetate; Cyclophosphamide/glatiramer acetate; Delmitide acetate; Depot leuprolide acetate 3.75 mg; Desmopressin acetate; Desmopressin acetate trihydrate; Device: cellulose acetate with petrolatum; Dichloroacetate; Dichloroacetate sodium; Dirucotide acetate; Edratide acetate; Etiprednol dicloacetate; Experimental glatiramer acetate; Flecainide acetate; Glatiramer acetate; Glatiramer acetate (copaxone®); Glatiramer acetate (db); Glatiramer acetate (ga); Glatiramer acetate (ga) 40 mg; Glatiramer acetate (gtr); Glatiramer acetate (ol); Glatiramer acetate 150mg enteric coated tablets; Glatiramer acetate 150mg enteric-coated (gastro-resistant) tablets; Glatiramer acetate 20 mg; Glatiramer acetate 20 mg, with mitoxantrone; Glatiramer acetate 20 mg/0.5 ml; Glatiramer acetate 40 mg; Glatiramer acetate [ga]; Glatiramer acetate injection with oral cetirizine hydrochloride; Glatiramer acetate with minocycline; Glatiramer acetate, (copaxone®); Glatiramer acetate, ifn-beta 1a (im), ifn-beta 1a (subcutaneous), and ifn-beta 1b; Glatiramer acetate, n-acetylcysteine; Gonadorelin acetate and triptorelin acetate; Human interferon beta-1a and glatiramer acetate; Hydrocortisone acetate; Hydrocortisone sodium acetate; L-lysyl-d-prolyl-l-threonine acetate; L-lysyl-d-prolyl-lthreonine acetate, lyophilisate; Lanreotide acetate; Lapaquistat acetate and current lipid-lowering treatment; Leuprolide acetate (la); Leuprolide acetate 11.25 mg; Leuprolide acetate 3 month depot; Leuprolide acetate 30 mg; Leuprolide acetate 45 mg; Leuprolide acetate depot; Leuprorelin acetate; Leuprorelin acetate 3.75mg injection; Loestrin (norethindrone acetate and ethinyl estradiol); Loestrin 1.5/30 (1.5 mg norethindrone acetate/30 µg ethinyl estradiol); Luphere depot 3.75mg(leuprolide acetate 3.75mg); Lupron (leuprolide acetate); Macimorelin acetate; Megestrol acetate; Megestrol acetate tablet; Methylprednisolone acetate; Nomegestrol acetate; Octreotide acetate; Oxaloacetate (oaa); Phosphate and betamethasone acetate, 2 ml.; Plovamer acetate; Plovamer acetate 0.5 milligram (mg); Plovamer acetate 10 mg; Plovamer acetate 20 mg; Plovamer acetate 3 mg; Prednisolone acetate; Prednisone acetate; Prednisone acetate tablets; Procedure: warm compress prior to injection of glatiramer acetate; Sodium acetate; Sodium-[o-[(2,6-dichlorophenyl)-amino]- phenyl]-acetate; Sodium-[o-[(2,6-dichlorophenyl)-amino]-phenyl]-acetate; Sotrastaurin (inn) acetate; Tetracosactide acetate; Tetracosactide hexaacetate; Tocopherol acetate; Tocopheryl acetate; Triptorelin acetate and gonadorelin acetate; Ulipristal acetate; Zinc acetate; Zinc acetate (20mg/d); Zinc acetate dihydrate; Zuretinol acetate; [n-trans-3-hexenoyl] human growth hormone releasing factor (1-44) acetate;  -  -  -  [43]  1 ,  2 ,  6 , 10, 13, 35, 40, 46, 49, 51, 60, 64, 67, 70, 71, 73, 75, 76, 78, 79, 81, 83, 85, 86, 88, 90, 96, 97, 113, 145, 156, 162, 171, 206, 222, 224, 225, 227, 235, 265, 288, 298, 299 💬
 2  Acipimox [1] Acipimox;  [1] D07190 💬  -  -  [2] 78, 265 💬
 3  Albumin human - [2] D02792
D05424 💬		  -  -  [3]  2 , 78, 96 💬
 4  Amitriptyline [4] Amitriptyline; Amitriptyline hydrochloride; Amitriptyline, fluoxetine and tramadol alone (control group); Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group);  [2] D00809
D07448 💬		 [2] SLC6A2, SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle  [4] 78, 97, 226, 299 💬
 5  Anastrozole [2] Anastrozole; Arimidex (anastrozole);  [1] D00960 💬 [1] CYP19A1 💬 [3] Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis  [3] 78, 86, 193 💬
 6  Arginine [13] Ar401959 l-arginine; Arginine; Etrasimod l-arginine; Growth hormone releasing hormone (ghrh) and arginine; L-arginine; Ng-monomethyl-l-arginine; Ng-monomethyl-l-arginine (drug); Other: ghrh plus arginine test; Other: glucose -potentiated arginine (gpa) stimulation tests; Procedure: arginine and clonidine stimulation testing; Procedure: arginine stimulation test after each limb; Procedure: ghrh/arginine stimulation testing; Vasopressin, arginine;  [1] D02982 💬  -  -  [9] 46, 67, 78, 96, 97, 113, 210, 251, 299 💬
 7  ARX201 [1] Arx201;  -  -  -  [1] 78 💬
 8  Caffeine [6] Caffeine; Caffeine 100 mg; Caffeine 100-200 mg bid; Caffeine alkaloid; Dextromethorphan and caffeine; Other: caffeine;  [2] D00528
D01453 💬		 [11] ADORA1, ADORA2A, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 [22] Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [9]  2 ,  6 , 13, 21, 46, 78, 96, 97, 265 💬
 9  Chloride ion - -  -  -  [25]  6 , 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 78, 96, 97, 127, 168, 171, 193, 227, 228, 271, 288, 296, 297, 299 💬
 10  Clonidine [5] Clonidine; Clonidine hcl cf 0,150 mg, tabletten; Clonidine hydrochloride; Device: clonidine (catapressan); Procedure: arginine and clonidine stimulation testing;  [2] D00281
D00604 💬		 [3] ADRA2A, ADRA2B, ADRA2C 💬 [2] Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway  [2]  6 , 78 💬
 11  Corticotropin [8] Adrenocorticotropin hormone; Corticotropin; Corticotropin-releasing hormone; H.p. acthar gel (repository corticotropin injection); Other: corticotropin releasing hormone (crh); Ovine corticotropin-releasing hormone (ocrh); Repository corticotropin injection; Repository corticotropin injection -treatment extension;  [1] D00146 💬 [1] MC2R 💬 [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [13]  2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬
 12  Dextromethorphan [10] Dextromethorphan; Dextromethorphan 30 mg; Dextromethorphan and caffeine; Dextromethorphan hbr and quinidine sulfate; Dextromethorphan hydrobromide; Dextromethorphan hydrobromide 20 mg and quinidine sulfate 10 mg; Dextromethorphan hydrobromide 30 mg and quinidine sulfate 10 mg; Dextromethorphan/quinidine; Dextromethorphan/quinidine 20mg/10mg (dm/q 20mg/10mg); Dimebon + dextromethorphan;  [3] D00848
D03742
D03744 💬		 [6] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D, SIGMAR1 💬 [20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway  [11]  2 ,  6 ,  8 , 13, 21, 46, 78, 85, 96, 97, 156 💬
 13  Donepezil [7] Donepezil; Donepezil hci (drug); Donepezil hydrochloride; Donepezil sandoz; Other: [11c]donepezil pet; Pridia (donepezil hydrochloride) 5mg; Prior donepezil 5mg;  [2] D00670
D07869 💬		 [1] ACHE 💬 [2] Cholinergic synapse, Glycerophospholipid metabolism  [9]  5 ,  6 , 13, 46, 78, 124, 127, 156, 206 💬
 14  Fluoxetine [4] Amitriptyline, fluoxetine and tramadol alone (control group); Fluoxetine; Fluoxetine hydrochloride; Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group);  [2] D00326
D00823 💬		 [1] SLC6A4 💬 [2] Serotonergic synapse, Synaptic vesicle cycle  [6] 13, 17, 78, 86, 179, 206 💬
 15  Gelatin [8] Arimoclomol (hard gelatine capsule); Bio-enhanced curcumin soft gelatin capsule; Gelatin; Gelatine; Neoral soft gelatin capsules; Tafamidis meglumine 20 mg soft gelatin capsules; Tafamidis meglumine 20mg soft gelatin capsule (clinical trial image); Tafamidis meglumine 20mg soft gelatin capsule (commerical image);  [2] D00115
D06892 💬		  -  -  [6] 19, 28, 78, 97, 269, 299 💬
 16  Glucagon [2] Glucagon; Procedure: glucagon stimulation test and insulin tolerance test;  [2] D00116
D02118 💬		 [1] GCGR 💬 [2] Glucagon signaling pathway, Neuroactive ligand-receptor interaction  [1] 78 💬
 17  Hydrocortisone [31] 90 mg hydrocortisone acetate suppository with sephure suppository applicator; Combination oral budesonide and rectal hydrocortisone; Combination product: twice daily 90 mg hydrocortisone acetate suppository administered with sephure applicator; Conventional glucocorticoids (immediate release hydrocortisone, cortisone acetate, prednisone, prednisolone, dexamethasone); Cortef (hydrocortisone); Dual release hydrocortisone (plenadren); Hydrocortisone; Hydrocortisone (solucortef); Hydrocortisone 100mg/ml; Hydrocortisone 10mg; Hydrocortisone 10mg tablet; Hydrocortisone 10mg tablets; Hydrocortisone 20mg tablets; Hydrocortisone acetate; Hydrocortisone cream; Hydrocortisone cream 1%; Hydrocortisone cream 10mg/g fna fagron; Hydrocortisone hydrogen succinate; Hydrocortisone modified release capsules; Hydrocortisone roussel; Hydrocortisone sodium acetate; Hydrocortisone sodium phosphate; Hydrocortisone sodium succinate; Hydrocortisone tablet 2.5 mg; Hydrocortisone takeda, tabletter; Mesalazine with hydrocortisone sodium succinate; Other: hydrocortisone; Procedure: hydrocortisone withdrawal; Solu-cortef (hydrocortisone); Subcutaneous hydrocortisone; Subcutaneous hydrocortisone 10mg;  [1] D00088 💬 [1] NR3C1 💬 [1] Neuroactive ligand-receptor interaction  [9]  6 , 46, 53, 75, 78, 81, 83, 97, 299 💬
 18  Lenomorelin - -  -  -  [3]  6 , 78, 299 💬
 19  Levothyroxine [2] Levothyroxine; Other: levothyroxine;  [2] D01010
D08125 💬		 [2] THRA, THRB 💬 [2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway  [4] 19, 49, 78, 222 💬
 20  Liothyronine [3] Liothyronine; Liothyronine i 131; Liothyronine sodium;  [2] D01011
D08128 💬		 [2] THRA, THRB 💬 [2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway  [4] 13, 78, 210, 212 💬
 21  Lonapegsomatropin [1] Lonapegsomatropin;  [1] D11486 💬 [1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway  [1] 78 💬
 22  Macimorelin [2] Macimorelin; Macimorelin acetate;  [1] D10563 💬 [1] GHSR 💬 [3] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [1] 78 💬
 23  Mecasermin [3] Mecasermin; Mecasermin [rdna origin] 10mg/ml solution; Mecasermina;  [2] D03297
D04870 💬		 [2] GHR, IGF1R 💬 [33] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway  [6] 65, 78, 96, 168, 265, 299 💬
 24  Methyl salicylate 2-ethylbutyrate - -  -  -  [1] 78 💬
 25  Niacin [6] Dose-establishing study 1 niacin 250mg; Dose-establishing study 1 niacin 500mg; Dose-establishing study 2 niacin 500mg; Niacin; Niacin first; Niacinamide;  [1] D00049 💬  -  -  [4]  6 , 78, 79, 265 💬
 26  Pegvisomant [1] Pegvisomant;  [1] D05394 💬 [1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway  [1] 78 💬
 27  Phosphate ion - -  -  -  [30]  2 ,  3 , 11, 12, 13, 28, 36, 46, 49, 51, 53, 60, 62, 65, 70, 78, 81, 83, 90, 96, 97, 164, 235, 256, 276, 283, 284, 285, 286, 299 💬
 28  Pioglitazone [6] Actos (pioglitazone); Pioglitazone; Pioglitazone 15 mg; Pioglitazone and tretinoin; Pioglitazone or metformin; Tretinoin and pioglitazone hcl;  [2] D00945
D08378 💬		 [1] PPARG 💬 [9] AMPK signaling pathway, Huntington disease, Longevity regulating pathway, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer  [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
 29  Polyethylene glycol [6] 2l polyethylene glycol/ascorbic acid; C-type natriuretic peptide conjugated to multi-arm polyethylene glycol carrier through a cleavable linker; Polyethylene glycol; Polyethylene glycol 3350; Teriparatide conjugated to a multiarm polyethylene glycol carrier molecule through a cleavable linker; Treatment with polyethylene glycol (macrogol 4000);  [1] D03370 💬  -  -  [11]  6 , 13, 46, 65, 78, 96, 97, 235, 240, 276, 299 💬
 30  Sodium chloride [24] 0.9% sodium chloride; 0.9% sodium chloride (normal saline); 0.9% sodium chloride injection; 0.9% w/v isotonic sodium chloride solution; 0.9% w/v sodium chloride solution; Isotonic sodium chloride solution; Other: 0.9% sodium chloride; Other: 0.9ml sodium chloride; Other: sodium chloride; Physiological serum (sodium chloride); Procedure: 9% sodium chloride (nacl) iv; Sodium chloride; Sodium chloride (7%); Sodium chloride 0,9%; Sodium chloride 0.9%; Sodium chloride 6%; Sodium chloride 7%; Sodium chloride ph. eur.; Sodium chloride solution; Sodium chloride solution 0.9%; Sodium chloride solvent; Sodium pyruvate in 0.9% sodium chloride solution; Solucion de cloruro de sodio sodium chloride solution; Solvente cloruro de sodio sodium chloride solvent;  [1] D02056 💬  -  -  [20]  6 , 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 78, 96, 168, 193, 227, 228, 271, 288, 299 💬
 31  Somapacitan [4] Somapacitan; Somapacitan 10 mg/1.5ml pds290; Somapacitan 15 mg/1.5ml pds290; Somapacitan 5 mg/1.5ml pds290;  [1] D11194 💬 [1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway  [1] 78 💬
 32  Somatorelin [1] Somatorelin;  [1] D08523 💬 [1] GHRHR 💬 [2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction  [2] 13, 78 💬
 33  Somatostatin [2] Long-acting somatostatin; Somatostatin;  [1] D07431 💬 [5] SSTR1, SSTR2, SSTR3, SSTR4, SSTR5 💬 [4] Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [2] 67, 78 💬
 34  Somatotropin [3] Recombinant human somatotropin; Somatotropin; Somatotropine;  [1] D02691 💬 [1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway  [20]  2 ,  3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬
 35  Somatrogon [2] Somatrogon; Somatrogon (genetical recombination);  [1] D10990 💬  -  -  [1] 78 💬
 36  Somatropin pegol - -  -  -  [1] 78 💬
 37  Somavaratan [2] Somavaratan; Somavaratan (vrs-317);  [1] D11193 💬 [1] GHR 💬 [5] Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway  [1] 78 💬
 38  Strontium ranelate [1] Strontium ranelate;  [1] D08468 💬  -  -  [1] 78 💬
 39  Tesamorelin [2] Tesamorelin; Tesamorelin (egrifta);  [2] D06655
D09015 💬		 [1] GHRHR 💬 [2] Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction  [2] 78, 265 💬
 40  Testosterone [13] Androgel 10 grams of gel containing 100 mg of testosterone; Nebido® testosterone undecanoate 1000 mg/4 ml solution for injection; Procedure: testosterone injection; Sustanon (testosterone); Testosterone; Testosterone decanoate; Testosterone enanthate; Testosterone isocaproate; Testosterone phenylpropionate; Testosterone plus somatropin; Testosterone propionate; Testosterone undecanoate; Transdermal testosterone gel;  [6] D00075
D00957
D00958
D00959
D06085
D06087 💬		 [1] AR 💬 [3] Oocyte meiosis, Pathways in cancer, Prostate cancer  [8]  1 ,  2 ,  3 , 13, 60, 78, 113, 265 💬
 41  Tetracosactide [5] Depot tetracosactide; Tetracosactide; Tetracosactide acetate; Tetracosactide hexaacetate; Tetracosactide hexacetaat;  [1] D00284 💬 [1] MC2R 💬 [5] Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway  [5] 78, 83, 113, 145, 222 💬
 42  Thyroid, porcine - -  -  -  [1] 78 💬
 43  Tiratricol [2] Tiratricol; Téatrois (tiratricol);  [1] D07214 💬 [2] THRA, THRB 💬 [2] Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway  [2] 78, 139 💬
 44  Tramadol [6] Amitriptyline, fluoxetine and tramadol alone (control group); Sc recombinant growth hormone + amitriptyline, fluoxetine and tramadol (treated group); Tramadol; Tramadol /acetaminophen; Tramadol hydrochloride + acetaminophen; Tramadol with ropivacaine;  [2] D01355
D08623 💬		 [1] OPRM1 💬 [3] Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction  [5] 46, 70, 78, 226, 271 💬
 45  Water [31] 15 o water; 15-o labeled water; 5% glucose water solution; Behavioral: diet and water adjustment; Behavioral: water tracking; Cholecalciferol concentrate (water-dispersible form); Device: manual toothbrush and water flosser (philips sonicare airfloss); Device: sonic toothbrush (philips sonicare) and water flosser (philips sonicare airfloss); Dextrose, 5% in water; High water intake; Lactose in water; Other: ad libitum water intake; Other: dead sea solar and water treatment; Other: dextrose water 5%; Other: exercise followed cold water immersion; Other: harkány medicinal water; Other: high water intake; Other: potable water; Other: water; Other: water prescription; Pl 12185/0002 & pl 12185/0005(water for injection); Procedure: water exercises; Pseudoephedrine + 480 ml water; Pseudoephedrine + 50 ml water; Sterile water; Sterile water for injection; Sterilised water for injections; Water; Water for injection; Water for injections; Water for injections, ep;  [1] D00001 💬  -  -  [22]  2 ,  5 ,  6 , 13, 17, 19, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299 💬