Target Gene/Pathway💬 Info on mouse-over

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D00639 💬	Mexiletine	[5]  1 ,  2 , 10, 113, 114 💬
2	Adrenergic signaling in cardiomyocytes 💬	[1] SCN5A 💬	D08215 💬	Mexiletine	[5]  1 ,  2 , 10, 113, 114 💬
3	Breast cancer 💬	[1] PGR 💬	D09567 💬	Ulipristal	[1] 10 💬
4	cAMP signaling pathway 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[5]  2 , 10, 13, 18, 149 💬
5	cGMP-PKG signaling pathway 💬	[1] OPRD1 💬	D02095 💬	Naltrexone	[13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
6	cGMP-PKG signaling pathway 💬	[1] OPRD1 💬	D05113 💬	Naltrexone	[13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
7	Dopaminergic synapse 💬	[1] SCN1A 💬	D00639 💬	Mexiletine	[5]  1 ,  2 , 10, 113, 114 💬
8	Dopaminergic synapse 💬	[1] SCN1A 💬	D08215 💬	Mexiletine	[5]  1 ,  2 , 10, 113, 114 💬
9	Estrogen signaling pathway 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[5]  2 , 10, 13, 18, 149 💬
10	Estrogen signaling pathway 💬	[1] OPRM1 💬	D02095 💬	Naltrexone	[13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
11	Estrogen signaling pathway 💬	[1] OPRM1 💬	D05113 💬	Naltrexone	[13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
12	Estrogen signaling pathway 💬	[1] PGR 💬	D09567 💬	Ulipristal	[1] 10 💬
13	GABAergic synapse 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[5]  2 , 10, 13, 18, 149 💬
14	GnRH secretion 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[5]  2 , 10, 13, 18, 149 💬
15	Morphine addiction 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[5]  2 , 10, 13, 18, 149 💬
16	Morphine addiction 💬	[1] OPRM1 💬	D02095 💬	Naltrexone	[13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
17	Morphine addiction 💬	[1] OPRM1 💬	D05113 💬	Naltrexone	[13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
18	Neuroactive ligand-receptor interaction 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[5]  2 , 10, 13, 18, 149 💬
19	Neuroactive ligand-receptor interaction 💬	[3] OPRD1, OPRK1, OPRM1 💬	D02095 💬	Naltrexone	[13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
20	Neuroactive ligand-receptor interaction 💬	[3] OPRD1, OPRK1, OPRM1 💬	D05113 💬	Naltrexone	[13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
21	Oocyte meiosis 💬	[1] PGR 💬	D09567 💬	Ulipristal	[1] 10 💬
22	Progesterone-mediated oocyte maturation 💬	[1] PGR 💬	D09567 💬	Ulipristal	[1] 10 💬
23	Sphingolipid signaling pathway 💬	[1] OPRD1 💬	D02095 💬	Naltrexone	[13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
24	Sphingolipid signaling pathway 💬	[1] OPRD1 💬	D05113 💬	Naltrexone	[13]  6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬
25	Taste transduction 💬	[2] GABBR1, GABBR2 💬	D00241 💬	Baclofen	[5]  2 , 10, 13, 18, 149 💬
26	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D00639 💬	Mexiletine	[5]  1 ,  2 , 10, 113, 114 💬
27	Taste transduction 💬	[3] SCN2A, SCN3A, SCN9A 💬	D08215 💬	Mexiletine	[5]  1 ,  2 , 10, 113, 114 💬

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