Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
2 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
3 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
4 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
5 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
6 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
7 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
8 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
9 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
10 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
11 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
12 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
13 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 16 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
14 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 16 diseases |
CA1 [13] CA1, CA12, CA13, CA14, CA2, CA3, CA4, CA5A, CA5B, CA6, CA7, CA8, CA9 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
15 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CA2 [1] CA2 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
16 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CA2 [1] CA2 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
17 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 17 diseases |
CA2 [2] CA2, CA4 💬 |
D00218 D00218 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
18 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 17 diseases |
CA2 [2] CA2, CA4 💬 |
D01196 D01196 💬 |
Acetazolamide | 013 [7] 13, 86, 90, 115, 155, 225, 230 💬 |
19 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
GABRA1 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
20 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
GABRB1 [3] GABRB1, GABRB2, GABRB3 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |
21 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
GABRA1 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 |
D00293 D00293 💬 |
Diazepam | 046 [3] 46, 155, 298 💬 |