Target Gene/Pathway💬 Info on mouse-over

No.	KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related	KEGG GENES	KEGG DRUG	DrugBank	Disease ID
1	Adrenergic signaling in cardiomyocytes 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
2	AGE-RAGE signaling pathway in diabetic complications 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
3	Aldosterone synthesis and secretion 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
4	Aldosterone-regulated sodium reabsorption 💬	[1] NR3C2 💬	D00443 💬	Spironolactone	[7] 58, 67, 86, 113, 210, 218, 225 💬
5	AMPK signaling pathway 💬	[1] HMGCR 💬	D00892 💬	Fluvastatin	[3] 79, 218, 222 💬
6	AMPK signaling pathway 💬	[1] HMGCR 💬	D07983 💬	Fluvastatin	[3] 79, 218, 222 💬
7	Apelin signaling pathway 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
8	Bile secretion 💬	[1] HMGCR 💬	D00892 💬	Fluvastatin	[3] 79, 218, 222 💬
9	Bile secretion 💬	[1] HMGCR 💬	D07983 💬	Fluvastatin	[3] 79, 218, 222 💬
10	Calcium signaling pathway 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
11	cGMP-PKG signaling pathway 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
12	Chagas disease 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
13	Chagas disease 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
14	Chagas disease 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
15	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
16	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
17	Coronavirus disease - COVID-19 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
18	Coronavirus disease - COVID-19 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
19	Cortisol synthesis and secretion 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
20	Cushing syndrome 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
21	Diabetic cardiomyopathy 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
22	Diabetic cardiomyopathy 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
23	Diabetic cardiomyopathy 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
24	Diabetic cardiomyopathy 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
25	Endocrine and other factor-regulated calcium reabsorption 💬	[1] VDR 💬	D00930 💬	Paricalcitol	[3] 19, 66, 218 💬
26	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
27	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
28	Hypertrophic cardiomyopathy 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
29	Metabolic pathways 💬	[1] HMGCR 💬	D00892 💬	Fluvastatin	[3] 79, 218, 222 💬
30	Metabolic pathways 💬	[1] HMGCR 💬	D07983 💬	Fluvastatin	[3] 79, 218, 222 💬
31	Mineral absorption 💬	[1] VDR 💬	D00930 💬	Paricalcitol	[3] 19, 66, 218 💬
32	Neuroactive ligand-receptor interaction 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
33	Parathyroid hormone synthesis, secretion and action 💬	[1] VDR 💬	D00930 💬	Paricalcitol	[3] 19, 66, 218 💬
34	Pathways in cancer 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
35	Phospholipase D signaling pathway 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
36	Renin secretion 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
37	Renin secretion 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
38	Renin secretion 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
39	Renin secretion 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
40	Renin-angiotensin system 💬	[1] ACE 💬	D00620 💬	Benazepril	[4] 49, 57, 218, 224 💬
41	Renin-angiotensin system 💬	[1] ACE 💬	D07499 💬	Benazepril	[4] 49, 57, 218, 224 💬
42	Renin-angiotensin system 💬	[1] ACE 💬	D00421 💬	Ramipril	[7] 46, 49, 66, 67, 113, 218, 257 💬
43	Renin-angiotensin system 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬
44	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D00892 💬	Fluvastatin	[3] 79, 218, 222 💬
45	Terpenoid backbone biosynthesis 💬	[1] HMGCR 💬	D07983 💬	Fluvastatin	[3] 79, 218, 222 💬
46	Tuberculosis 💬	[1] VDR 💬	D00930 💬	Paricalcitol	[3] 19, 66, 218 💬
47	Vascular smooth muscle contraction 💬	[1] AGTR1 💬	D00400 💬	Valsartan	[7] 57, 58, 66, 75, 218, 222, 224 💬

Back to top