Target Gene/Pathway💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | Disease ID |
1 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
ACE [1] ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
2 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
ACE [1] ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
3 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
4 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
C5AR1 [1] C5AR1 💬 |
D11093 D11093 💬 |
Avacopan | 043 [4] 43, 44, 222, 223 💬 |
5 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [5] 64, 66, 109, 222, 223 💬 |
6 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
SERPINC1 [2] SERPINC1, SERPIND1 💬 |
D08547 D08547 💬 |
Sulodexide | 013 [5] 13, 51, 223, 271, 288 💬 |
7 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
ACE [1] ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
8 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
ACE [1] ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
9 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
10 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
C5AR1 [1] C5AR1 💬 |
D11093 D11093 💬 |
Avacopan | 043 [4] 43, 44, 222, 223 💬 |
11 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [5] 64, 66, 109, 222, 223 💬 |
12 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
ACE [1] ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
13 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
ACE [1] ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
14 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
REN [1] REN 💬 |
D03208 D03208 💬 |
Aliskiren | 066 [4] 66, 167, 222, 223 💬 |
15 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
16 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
ACE [1] ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
17 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
ACE [1] ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
18 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
19 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
C5AR1 [1] C5AR1 💬 |
D11093 D11093 💬 |
Avacopan | 043 [4] 43, 44, 222, 223 💬 |
20 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
21 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
C5AR1 [1] C5AR1 💬 |
D11093 D11093 💬 |
Avacopan | 043 [4] 43, 44, 222, 223 💬 |
22 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
23 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
24 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ACE [1] ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
25 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ACE [1] ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
26 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
REN [1] REN 💬 |
D03208 D03208 💬 |
Aliskiren | 066 [4] 66, 167, 222, 223 💬 |
27 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
ACE [1] ACE 💬 |
D00621 D00621 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
28 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
ACE [1] ACE 💬 |
D07892 D07892 💬 |
Enalapril | 019 [7] 19, 46, 66, 113, 210, 222, 223 💬 |
29 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
REN [1] REN 💬 |
D03208 D03208 💬 |
Aliskiren | 066 [4] 66, 167, 222, 223 💬 |
30 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |
31 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
C5AR1 [1] C5AR1 💬 |
D11093 D11093 💬 |
Avacopan | 043 [4] 43, 44, 222, 223 💬 |
32 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
MASP2 [1] MASP2 💬 |
D11531 D11531 💬 |
Narsoplimab | 064 [5] 64, 66, 109, 222, 223 💬 |
33 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
C5 [1] C5 💬 |
D03940 D03940 💬 |
Eculizumab | 011 [8] 11, 13, 14, 61, 62, 109, 222, 223 💬 |