DDrare: Database of Drug Development for Rare Diseases

210. 単心室症
［臨床試験数：47，薬物数：54（DrugBank：23），標的遺伝子数：32，標的パスウェイ数：66］

Searched query = "Single Ventricle", "SV", "Single ventricle heart defect", "Univentricular heart", "UVH", "Single ventricular circulation syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = ACETYLSALICYLIC ACID; ACT-064992; Acetylsalicylic acid; Administration of an ACE-inhibitor or not; Aesculus Hippocastanum / Horse Chestnut; Ambrisentan; Arginine; Aspirin; Autologous Tissue-Engineered Vascular Graft; BAY 59-7939; Bosentan; Carvedilol; Colchicine; Digoxin; Enalapril; Eplerenone; Horse chestnut; JNJ-39039039; Liothyronine; Liothyronine I 131; MACITENTAN; MPC; MZ101; Macitentan; Milk; Mysildecard; Mysildecard 20 mg; Nitric Oxide; Normal Saline; ODSH at 0.125 mg/kg/h; ODSH at 0.250 mg/kg/h; ODSH at 0.375 mg/kg/h; Opsumit; Opsumit®; Other: Human Milk Derived Fortifier; Other: Human/Bovine Milk; RIVAROXABAN; Rexlemestrocel-L; Rivaroxaban; SCRM001_TEVG; Sildenafil; Sildenafil by injection; Spironolactone; Spironolactone (drug); Sugar pill; Tadalafil; Tadalafil Citrate; Tracleer; Treprostinil; Udenafil; Vasopressin; Vasopressin, Arginine; Vitamin C; Xarelto

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02860702 (ClinicalTrials.gov)	July 2016	28/7/2016	Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology	A Randomized Controlled Trial to Evaluate Growth Velocity and Clinical Outcomes of Infants With Single Ventricle Physiology Fed an Exclusive Human Milk Diet With Early Nutritional Fortification Following Surgical Repair	Congenital Heart Defect	Other: Human Milk Derived Fortifier;Other: Human/Bovine Milk	The University of Texas Health Science Center at San Antonio	Prolacta Bioscience;Baylor College of Medicine;Children's Hospital Medical Center, Cincinnati;Columbia University;University of Oklahoma;Ann & Robert H Lurie Children's Hospital of Chicago;Cook Children's Medical Center;Children's Hospital of Orange County;University of Texas;University of Florida	Recruiting	N/A	7 Days	All	100	N/A	United States

No.

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Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

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NCT02860702
(ClinicalTrials.gov)

July 2016

28/7/2016

Exclusive Human Milk Feeding in Infants With Single Ventricle Physiology

A Randomized Controlled Trial to Evaluate Growth Velocity and Clinical Outcomes of Infants With Single Ventricle Physiology Fed an Exclusive Human Milk Diet With Early Nutritional Fortification Following Surgical Repair

Congenital Heart Defect

Other: Human Milk Derived Fortifier;Other: Human/Bovine Milk

The University of Texas Health Science Center at San Antonio

Prolacta Bioscience;Baylor College of Medicine;Children's Hospital Medical Center, Cincinnati;Columbia University;University of Oklahoma;Ann & Robert H Lurie Children's Hospital of Chicago;Cook Children's Medical Center;Children's Hospital of Orange County;University of Texas;University of Florida

Recruiting

N/A

7 Days

All

100

N/A

United States