DDrare: Database of Drug Development for Rare Diseases

225. 先天性腎性尿崩症
［臨床試験数：12，薬物数：45（DrugBank：17），標的遺伝子数：30，標的パスウェイ数：63］

Searched query = "Congenital nephrogenic diabetes insipidus", "Hereditary nephrogenic diabetes insipidus", "Nephrogenic diabetes insipidus"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = ACETAZOLAMIDE; Acetate; Acetazolamide; Acetazolamide Sandoz 250; Adempas; Amiloride; Atorvastatin; CALCITONIN (SALMON); Calcitonin; Chlorothiazide; Confortid; DESMOPRESSIN ACETATE TRIHYDRATE; Desmopressin; Desmopressin acetate trihydrate; Desmopressine; Desmopressine nasal spray 10 mg/ml, flacon 60 doses; Esidrix; FLUCONAZOLE; Fluconazole; HYDROCHLOROTHIAZIDE; Hydrochloorthiazide; Hydrochlorothiazide; Hydrochlorothiazide/amiloride; INDOMETACIN; Indometacin; Indomethacin; Losec; Magnesium; Metformin; Miacalcic; Midamor; OMEPRAZOLE MAGNESIUM; Omeprazole; RIOCIGUAT; Riociguat; SILDENAFIL; SILDENAFIL CITRATE; SPIRONOLACTONE; SUB21605; Salmon; Sildenafil; Spirix; Spironolactone; Tolvaptan; Viagra

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2016-001591-30-DK (EUCTR)	06/11/2017	09/03/2017	Treatment of congenital nephrogenic diabetes insipidus with riociguat or sildenafil	Treatment of congenital nephrogenic diabetes insipidus with a guanylate cyclase stimulator, riociguat or a phosphodiesterase type 5 inhibitor, sildenafil	Nephrogenic diabetes insipidus because of AVP2R-mutation MedDRA version: 20.0;Level: LLT;Classification code 10012626;Term: Diabetes nephrogenic (excludes glycosuria);System Organ Class: 100000004857 ;Therapeutic area: Diseases [C] - Hormonal diseases [C19]		Odense University Hospital	NULL	Not Recruiting			Female: no Male: yes	2	Phase 2	Denmark

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enrollment

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Public_title

Scientific_title

Condition

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Primary_
sponsor

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Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
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EUCTR2016-001591-30-DK
(EUCTR)

06/11/2017

09/03/2017

Treatment of congenital nephrogenic diabetes insipidus with riociguat or sildenafil

Treatment of congenital nephrogenic diabetes insipidus with a guanylate cyclase stimulator, riociguat or a phosphodiesterase type 5 inhibitor, sildenafil

Nephrogenic diabetes insipidus because of AVP2R-mutation
MedDRA version: 20.0;Level: LLT;Classification code 10012626;Term: Diabetes nephrogenic (excludes glycosuria);System Organ Class: 100000004857 ;Therapeutic area: Diseases [C] - Hormonal diseases [C19]

Odense University Hospital

NULL

Not Recruiting

Female: no
Male: yes

Phase 2

Denmark