299. 嚢胞性線維症
［臨床試験数：1,592，薬物数：1,539（DrugBank：255），標的遺伝子数：81，標的パスウェイ数：162］
Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT02498535 (ClinicalTrials.gov) | February 22, 2017 | 12/7/2015 | Efficacy and Safety of Inhaled Nitric Oxide (NO) in Cystic Fibrosis (CF) Patients | Prospective, Randomized, Placebo Controlled Trial of the Efficacy and Safety of Inhaled Nitric Oxide (NO) in Cystic Fibrosis (CF) Patients | Cystic Fibrosis | Drug: Nitric Oxide 160 ppm | Novoteris, LLC | Cystic Fibrosis Foundation;Mallinckrodt | Recruiting | 18 Years | N/A | All | 60 | Phase 2 | United States;Canada |
| 2 | NCT01958944 (ClinicalTrials.gov) | December 2013 | 6/10/2013 | Evaluation of the Safety and Tolerability of Inhaled Nitric Oxide to Subjects With Cystic Fibrosis | Phase II Prospective, Open Labeled, Multi-Center, Evaluation of the Safety and Tolerability of Nitric Oxide Given Intermittently Via Inhalation to Subjects With Cystic Fibrosis | Cystic Fibrosis | Drug: Nitric oxide | Advanced Inhalation Therapies Ltd | Soroka University Medical Center;Schneider Children's Medical Center, Israel | Completed | 10 Years | N/A | Both | 9 | Phase 1;Phase 2 | Israel |
| 3 | NCT02295566 (ClinicalTrials.gov) | May 2011 | 20/8/2014 | RATNO, Reducing Antibiotic Tolerance Using Nitric Oxide in CF - a Phase 2 Pilot Study | RATNO (Reducing Antibiotic Tolerance Using NO) Reducing Antibiotic Tolerance Using Low Dose Nitric Oxide in Cystic Fibrosis - a Phase 2 Pilot Study | Cystic Fibrosis | Drug: Nitric Oxide;Drug: Control | University Hospital Southampton NHS Foundation Trust. | University of Southampton | Completed | 12 Years | N/A | Both | 12 | Phase 2 | United Kingdom |
| 4 | EUCTR2010-023529-39-GB (EUCTR) | 18/02/2011 | 31/12/2010 | Reducing antibiotic tolerance using low dose nitric oxide in cystic fibrosis – a phase 2 pilot study - RATNO (Reducing Antibiotic Tolerance using Nitric Oxide in CF) v 1.0 | Reducing antibiotic tolerance using low dose nitric oxide in cystic fibrosis – a phase 2 pilot study - RATNO (Reducing Antibiotic Tolerance using Nitric Oxide in CF) v 1.0 | Cystic Fibrosis | Trade Name: INOmax 400ppm mol/mol inhalation gas Product Name: Nitric Oxide Product Code: NO | Southampton University Hopsitals NHS Trust | NULL | Not Recruiting | Female: yes Male: yes | Phase 2 | United Kingdom | |||
| 5 | NCT01155115 (ClinicalTrials.gov) | January 2010 | 29/6/2010 | Inflammatory and Microbiologic Markers in Sputum: Comparing Cystic Fibrosis With Primary Ciliary Dyskinesia | Inflammatory and Microbiologic Markers in Sputum in Response to Pulmonary Exacerbation: Comparing Cystic Fibrosis With Primary Ciliary Dyskinesia | Cystic Fibrosis;Primary Ciliary Dyskinesia | Procedure: Sputum Collection;Procedure: Pulmonary Function Testing;Procedure: Exhaled Nitric Oxide | The Hospital for Sick Children | NULL | Completed | 6 Years | 18 Years | Both | 46 | N/A | Canada |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | NCT00570349 (ClinicalTrials.gov) | July 2004 | 6/12/2007 | Safety and Tolerability of Inhaled Nitric Oxide in Patients With Cystic Fibrosis | Safety and Tolerability of Inhaled Nitric Oxide in Patients With Cystic Fibrosis | Cystic Fibrosis | Drug: Nitric Oxide for Inhalation;Drug: Nitrogen | Mallinckrodt | NULL | Completed | 12 Years | N/A | All | 18 | Phase 1;Phase 2 | United States |