DDrare: Database of Drug Development for Rare Diseases

72. 下垂体性ADH分泌異常症
［臨床試験数：36，薬物数：22（DrugBank：5），標的遺伝子数：2，標的パスウェイ数：4］

Searched query = "Pituitary ADH secretion disorder", "Inappropriate antidiuretic hormone secretion", "Syndrome of inappropriate secretion of antidiuretic hormone", "Inappropriate ADH syndrome", "Syndrome of inappropriate ADH", "Central diabetes insipidus", "Syndrome of inappropriate secretion of ADH", "SIADH"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = C03XA01; Desmopressin; Desmopressin Oral Melt; Desmopressin intranasal; Empagliflozin; Empagliflozin 25 MG; Empagliflozin 25mg; Empagliflozin 25mg Tbl; IUPAC; Other: Fluid Restriction; Other: Induced hypotonic hyponatremia - SIAD model; SAMSCA*10CPR 15MG; SR121463B; Samsca; Satavaptan; Satavaptan (SR121463); Satavaptan (SR121463B); TOLVAPTAN; Tolvaptan; Tolvaptan Oral Tablet; Tolvaptan in euvolemic hyponatremia; Urea

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02729766 (ClinicalTrials.gov)	March 2016	24/3/2016	Effects of Empagliflozin an SGLT2-Inhibitor on Healthy Volunteers With Induced Hypotonic Hyponatremia - the DIVE Study	Effects of Empagliflozin an SGLT2-Inhibitor on Healthy Volunteers With Induced Hypotonic Hyponatremia - the DIVE Study	Inappropriate ADH Syndrome	Other: Induced hypotonic hyponatremia - SIAD model;Drug: Empagliflozin 25mg Tbl;Drug: Placebo P-Tablet	University Hospital, Basel, Switzerland	NULL	Completed	18 Years	65 Years	Both	15	Phase 2;Phase 3	Switzerland

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT02729766
(ClinicalTrials.gov)

March 2016

24/3/2016

Effects of Empagliflozin an SGLT2-Inhibitor on Healthy Volunteers With Induced Hypotonic Hyponatremia - the DIVE Study

Inappropriate ADH Syndrome

Other: Induced hypotonic hyponatremia - SIAD model;Drug: Empagliflozin 25mg Tbl;Drug: Placebo P-Tablet

University Hospital, Basel, Switzerland

NULL

Completed

18 Years

65 Years

Both

Phase 2;Phase 3

Switzerland