97. 潰瘍性大腸炎
[臨床試験数:2,269,薬物数:1,331(DrugBank:241),標的遺伝子数:114,標的パスウェイ数:181

Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
17 trials found
No.TrialIDDate_
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1NCT04202211
(ClinicalTrials.gov)
February 202013/12/2019FMT for Remission of Active Ulcerative Colitis in AdultsA Randomized Double-blind, Placebo-controlled Trial of Lyophilized Fecal Microbiota Transplantation for the Induction of Remission in Adults With Active Ulcerative ColitisUlcerative Colitis;Inflammatory Bowel DiseasesBiological: FMT oral;Biological: FMT enema;Other: Placebo oral;Other: Placebo enemaUniversity of British ColumbiaCrohn's and Colitis Canada;Vancouver Island Health AuthorityNot yet recruiting18 YearsN/AAll145Phase 2Canada
2NCT03998488
(ClinicalTrials.gov)
January 31, 202024/6/2019Examining the Efficacy of Fecal Microbiota Transplantation (FMT) and Dietary Fiber in Patients With Ulcerative ColitisA Randomized, Placebo-controlled Clinical Trial Examining the Efficacy of Fecal Microbiota Transplantation (FMT) and Subsequent Dietary Fiber in Patients With Moderate Ulcerative ColitisUlcerative Colitis;Inflammatory Bowel DiseasesDrug: Fecal Microbiota Transplantation;Dietary Supplement: Psyllium Husk PowderWeill Medical College of Cornell UniversityCrohn's and Colitis FoundationRecruiting18 Years89 YearsAll135Phase 2United States
3NCT03483246
(ClinicalTrials.gov)
June 18, 201926/2/2018Impact of Fecal Microbiota Transplantation in Ulcerative ColitisImpact of Fecal Microbiota Transplantation in Ulcerative Colitis: a Randomized, Sham Controlled TrialUlcerative ColitisDrug: Fecal Microbiota Transplantation (FMT);Drug: Sham-transplantation PlaceboAssistance Publique - Hôpitaux de ParisCRB-HUEP;Institut National de la Santé Et de la Recherche Médicale, FranceRecruiting18 Years75 YearsAll150Phase 3France
4NCT03477032
(ClinicalTrials.gov)
June 1, 201819/3/2018FMT in Inflammatory Bowel DiseaseFaecal Transplantation in Inflammatory Bowel DiseaseFaecal Microbiota Transplantation;Crohn Disease;Ulcerative Colitis;Microscopic ColitisBiological: Faecal Microbiota TransplantationSt Vincent's Hospital MelbourneNULLRecruiting18 Years65 YearsAll50Australia
5EUCTR2015-005753-12-GB
(EUCTR)
22/11/201702/08/2018A research study looking at faecal transplant as a treatment for ulcerative colitis, and the best way to use it in children and adults with the conditionProspective, open-label, randomised pilot study to assess two possible routes of Faecal Microbiota Transplant (FMT) delivery in patients with ulcerative colitis. - STOP-Colitis Pilot Trial Ulcerative colitis for at least 3 months prior to trial entry;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]Product Name: Faecal Microbiota Transplant
Product Code: FMT
INN or Proposed INN: faecal matter
University of BirminghamNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
30Phase 3United Kingdom
No.TrialIDDate_
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agemin
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6NCT03006809
(ClinicalTrials.gov)
March 2, 201721/12/2016Optimal Fecal Microbiota Transplant Dosing for Mild to Moderate Ulcerative ColitisOptimal Fecal Microbiota Transplant Dosing for Mild to Moderate Ulcerative ColitisUlcerative ColitisBiological: Fecal Microbiota Transplantation (FMT), OpenBiome;Other: pretreatment antibioticsNajwa ElnachefNULLRecruiting18 Years64 YearsAll40Phase 1United States
7JPRN-jRCTs031180415
01/02/201722/03/2019A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel diseaseSingle center non-randomized study: A trial of a combination therapy of fecal microbial transplantation and antibiotics for inflammatory bowel disease Inflammatory Bowel Disease (Ulcerative Colitis, Crohn's Disease)
Inflammatory Bowel Disease (Ulcerative Colitis, Crohn's Disease)
AFM therapy arm : three antibiotics, amoxicillin (1500 mg/day), fosfomycin (3000 mg/day) and metronidazole (750 mg/day) are administered orally to patients for 2 weeks. For pediatric patients, amoxicillin (50mg/kg), fosfomycin (120mg/kg) and metronidazole (20mg/kg) are administered orally for 2 weeks (the upper limit is the same amount as adults).
FMT arm : Approximately 150 to 250 g of donor stool is diluted with saline (500 mL) and filtered to remove crude components. The diluted and filtered fecal suspension is transferred into the patients colon from cecum to rectum during total colonoscopy. As usual examinations, the patient undergoes biopsy of inflammatory site.
A-FMT arm : Patient undergoes FMT two days after AFM therapy.
Ishikawa DaiNULLRecruiting>= 6age oldNot applicableBoth120N/AJapan
8NCT02516384
(ClinicalTrials.gov)
October 1, 201629/7/2015Fecal Microbiota Transplantation (FMT) in the Management of Ulcerative Colitis (UC)Fecal Microbiota Transplantation (FMT) in the Management of Ulcerative Colitis (UC)Ulcerative ColitisBiological: Fecal Microbiota TransplantationWeill Medical College of Cornell UniversityNULLCompleted18 YearsN/AAll20Phase 1United States
9NCT02330653
(ClinicalTrials.gov)
November 201529/12/2014Fecal Microbiota Transplant (FMT) in Pediatric Active Ulcerative Colitis and Pediatric Active Crohn's ColitisA Phase I/II, Double Blinded, Placebo Controlled, Single-center Study of Fecal Microbiota Transplant (FMT) for the Treatment of Active Pediatric Ulcerative Colitis and Pediatric Active Crohn's ColitisInflammatory Bowel Diseases;Ulcerative Colitis;Crohn DiseaseBiological: Fecal Microbiota Transplant (FMT);Biological: PlaceboStacy A. KahnNULLCompleted5 Years30 YearsAll15Phase 1;Phase 2United States
10NCT02335281
(ClinicalTrials.gov)
January 20157/1/2015Standardized Fecal Microbiota Transplantation for Inflammatory Bowel DiseaseEfficacy, Durability and Safety of Standardized Fecal Microbiota Transplantation for Severe Inflammatory Bowel DiseaseInflammatory Bowel Disease;Ulcerative Colitis;Crohn's DiseaseProcedure: FMT;Drug: MesalazineYanling WeiNULLRecruiting16 Years70 YearsBoth40Phase 2China
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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11NCT02108821
(ClinicalTrials.gov)
September 201421/3/2014Fecal Microbiota Transplantation in Pediatric PatientsA Study of Fecal Microbiota Transplantation in Pediatric Patients With Relapsed Inflammatory Bowel Disease.Inflammatory Bowel Diseases (IBD);Crohn's Disease (CD);Ulcerative Colitis (UC)Biological: Fecal Microbiota Transplantation (FMT)Children's Mercy Hospital Kansas CityUniversity of PittsburghCompleted2 Years22 YearsAll23Phase 1United States
12NCT02227342
(ClinicalTrials.gov)
July 201422/7/2014Fecal Microbiota Transplantation (FMT) in the Management of Active Ulcerative ColitisA Prospective, Single Center, Open Label Trial of Fecal Microbiota Transplantation (FMT) in the Management of Active Ulcerative ColitisUlcerative ColitisBiological: Fecal Microbiota TransplantUniversity of AlbertaNULLCompleted18 Years65 YearsBoth3Phase 1;Phase 2Canada
13NCT02049502
(ClinicalTrials.gov)
July 201427/1/2014FMT in Ulcerative Colitis-Associated PouchitisThe Use of Fecal Microbiota Transplantation in Patients With Ulcerative Colitis-associated PouchitisUlcerative Colitis Associated PouchitisBiological: biologically active human fecal microbiota;Procedure: sigmoidoscopyVirginia O. ShafferNULLCompleted18 Years65 YearsAll8Phase 2United States
14NCT01947101
(ClinicalTrials.gov)
February 201413/9/2013Fecal Microbiota Transplantation (FMT) for Treatment of Ulcerative Colitis in ChildrenA Phase I Study of Fecal Microbiota Transplantation (FMT) in Immunomodulator Dependent Pediatric Ulcerative Colitis (UC)Ulcerative ColitisBiological: Fecal Microbiota TransplantBaylor College of MedicineNULLCompleted12 Years20 YearsBoth6Phase 1United States
15NCT02033408
(ClinicalTrials.gov)
January 20143/12/2013Manipulating the Microbiome in IBD by Antibiotics and FMTManipulating the Microbiome in IBD by Antibiotics and Fecal Microbiota Transplantation (FMT): a Randomized Controlled TrialExacerbation of Ulcerative Colitis;Ulcerative Colitis, Active Severe;Crohn's ColitisDrug: AB (antibiotics);Drug: CS (corticosteroids) OnlyShaare Zedek Medical CenterNULLActive, not recruiting2 Years75 YearsAll28Phase 4Canada;Finland;Israel;Italy;Poland;Spain
No.TrialIDDate_
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16NCT01896635
(ClinicalTrials.gov)
November 20136/7/2013Faecal Microbiota Transplantation in Ulcerative ColitisFaecal Microbiota Transplantation for Chronic Active Ulcerative Colitis - A Randomised Double Blind Controlled Study of Efficacy & SafetyUlcerative Colitis;Inflammatory Bowel DiseaseBiological: FMT infusions;Other: Placebo infusionThe University of New South WalesNULLCompleted18 Years75 YearsBoth81Phase 2Australia
17NCT01790061
(ClinicalTrials.gov)
November 20129/2/2013Standardized Fecal Microbiota Transplantation for Ulcerative ColitisEfficacy, Durability and Safety of Standardized Fecal Microbiota Transplantation in Patients With Moderate to Severe Ulcerative ColitisBacteria;Microbiota;Fecal Microbiota Transplantation;Inflammatory Bowel Disease;Ulcerative ColitisProcedure: Standardized FMT;Drug: Traditional treatmentsThe Second Hospital of Nanjing Medical UniversityAir Force Military Medical University, ChinaRecruiting6 Years80 YearsAll500Phase 2;Phase 3China