DDrare: Database of Drug Development for Rare Diseases

Searched query = "Myelomeningocele", "Myeloschisis", "Myelocele", "Myelocystocele", "Syringomyelocele"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Atosiban; Botulinum A toxin; Device: In Utero Endoscopic Correction of Myelomeningocele IDE - Laparotomy/Uterine Exteriorization Technique; Device: In Utero Endoscopic Correction of Myelomeningocele IDE - Percutaneous Technique; Device: Minimally invasive fetoscopic repair of MMC; Device: Omnidirectional accelerometer monitor (3x3 cm and 16 g, Actical®, Philips Respironics); MMC; MONITOR; Placental Mesenchymal Stem Cells; Placental Mesenchymal Stem Cells seeded on a commercially available dural graft extracellular matrix; Procedure: Fetal surgery for MMC repair; Procedure: endoscopic repair of myelomeningocele before 26 SA; SA; Terbutaline; Uterine

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04027374 (ClinicalTrials.gov)	July 1, 2019	16/7/2019	Stress-associated Epigenetic Alterations in Newborns After Fetal Surgery	Epigenetic Alterations in Stress Regulation Genes Among Newborns After Fetal Surgery for Myelomeningocele Repair: An Exploratory Study	Meningomyelocele	Procedure: Fetal surgery for MMC repair	University Children's Hospital, Zurich	University of Zurich;Psychiatric University Hospital, Zurich	Recruiting	N/A	3 Months	All	90		Switzerland

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT04027374
(ClinicalTrials.gov)

July 1, 2019

16/7/2019

Stress-associated Epigenetic Alterations in Newborns After Fetal Surgery

Epigenetic Alterations in Stress Regulation Genes Among Newborns After Fetal Surgery for Myelomeningocele Repair: An Exploratory Study

Meningomyelocele

Procedure: Fetal surgery for MMC repair

University Children's Hospital, Zurich

University of Zurich;Psychiatric University Hospital, Zurich

Recruiting

N/A

3 Months

All

Switzerland