DDrare: Database of Drug Development for Rare Diseases

Searched query = "Wilson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = 64CuCl2; ALXN1840; Acetate; Artamin 150 mg; Artamin 250 mg; BIS-CHOLINE TETRATHIOMOLYBDATE; Bis-Choline Tetrathiomolybdate; Bis-choline TETRATHIOMOLYBDATE; Bupropion; Bupropion Hydrochloride; COPPER (64CU) CHLORIDE; Celecoxib; Chloride; Choline; Copper; Cuprior; Cuprior 150 mg film-coated tablets; Cuprior 150mg film-coated tablets; D-penicillamine; D-penicillamine 150mg; D-penicillamine 250 mg; DMPS; DMSA; Galactose; Gold; Metalcaptase® 150 mg gastro-resistant tablet; Metalcaptase® 300 mg gastro-resistant tablet; NPC-02; Nitrogen; None; Once a day Trientine; PEMINE - 150 MG CAPSULE RIGIDE 50 CAPSULE; PENICILLAMINE; Penicillamine; Procedure: Fibroscan; Procedure: Functional hepatic nitrogen clearance; Procedure: Liver biopsy; Procedure: Ultrasound; SoC Therapy; Standard of Care Medications; TETA; TETA 4HCL; TETA 4HCl; TETA.4HCI; TETA.4HCl; TRIENTINE DIHYDROCHLORIDE; Tetrathiomolybdate; Trientine; Trientine dihydrochloride; Trientine dihydrochloride 300mg capsules; Trientine tetrahydrochloride; WTX101; Wilzin; ZINC ACETATE DIHYDRATE; ZINC GLUCONATE; Zinc; Zinc acetate; Zinc gluconate; Zink Natur-Drogeriet

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2013-003564-31-IT (EUCTR)	14/07/2016	26/04/2018	A study to review Wilson disease patients who have previously been prescribed d- Penicillamine but were changed to trientine as treatment for their disease, and to follow them for a further 12 months.	Multicentre, Retrospective Study to Assess Long-Term Outcomes of Chelator-Based Treatment With Trientine in Wilson Disease Patients Withdrawn from Therapy With - N/A	Wilson disease, also known as hepatolenticular degeneration, a rare automsomal, recessively inherited disorder which results in chronic copper intoxication. MedDRA version: 20.0;Level: PT;Classification code 10019819;Term: Hepato-lenticular degeneration;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]	Trade Name: Trientine dihydrochloride 300mg capsules	UNIVAR LTD	NULL	Not Recruiting			Female: yes Male: yes	90	Phase 2	France;Greece;Spain;Germany;United Kingdom;Italy
2	EUCTR2013-003564-31-DE (EUCTR)	27/02/2014	22/10/2013	A study to review Wilson disease patients who have previously been prescribed d- Penicillamine but were changed to trientine as treatment for their disease, and to follow them for a further 12 months.	Multicentre, Retrospective and Prospective Study to Assess Long Term Outcomes of Chelator-Based Treatment With Trientine in Wilson Disease Patients Withdrawn from Therapy With d-Penicillamine	Wilson disease, also known as hepatolenticular degeneration, a rare automsomal, recessively inherited disorder which results in chronic copper intoxication. MedDRA version: 19.1;Level: LLT;Classification code 10047988;Term: Wilson's disease;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]	Trade Name: Trientine dihydrochloride 300mg capsules INN or Proposed INN: TRIENTINE DIHYDROCHLORIDE	Univar B.V.	NULL	Not Recruiting			Female: yes Male: yes	90	Phase 4	Germany;Italy

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

EUCTR2013-003564-31-IT
(EUCTR)

14/07/2016

26/04/2018

A study to review Wilson disease patients who have previously been prescribed d- Penicillamine but were changed to trientine as treatment for their disease, and to follow them for a further 12 months.

Multicentre, Retrospective Study to Assess Long-Term Outcomes of Chelator-Based Treatment With Trientine in Wilson Disease Patients Withdrawn from Therapy With - N/A

Wilson disease, also known as hepatolenticular degeneration, a rare automsomal, recessively inherited disorder which results in chronic copper intoxication.
MedDRA version: 20.0;Level: PT;Classification code 10019819;Term: Hepato-lenticular degeneration;System Organ Class: 10010331 - Congenital, familial and genetic disorders;Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]

Trade Name: Trientine dihydrochloride 300mg capsules

UNIVAR LTD

NULL

Not Recruiting

Female: yes
Male: yes

Phase 2

France;Greece;Spain;Germany;United Kingdom;Italy

EUCTR2013-003564-31-DE
(EUCTR)

27/02/2014

22/10/2013

Multicentre, Retrospective and Prospective Study to Assess Long Term Outcomes of Chelator-Based Treatment With Trientine in Wilson Disease Patients Withdrawn from Therapy With d-Penicillamine

Wilson disease, also known as hepatolenticular degeneration, a rare automsomal, recessively inherited disorder which results in chronic copper intoxication.
MedDRA version: 19.1;Level: LLT;Classification code 10047988;Term: Wilson's disease;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Nutritional and Metabolic Diseases [C18]

Trade Name: Trientine dihydrochloride 300mg capsules
INN or Proposed INN: TRIENTINE DIHYDROCHLORIDE

Univar B.V.

NULL

Not Recruiting

Female: yes
Male: yes

Phase 4

Germany;Italy