206. Fragile X syndrome
98 clinical trials,   73 drugs   (DrugBank: 27 drugs),   46 drug target genes,   57 drug target pathways

Searched query = "Fragile X syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
4 trials found
No.TrialIDDate_
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agemin
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agemax
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PhaseCountries
1NCT02680379
(ClinicalTrials.gov)
March 201625/1/2016Combined Treatment of Minocycline and Lovastatin to Treat Individuals With Fragile X SyndromeA Pilot Study Exploring the Safety and Synergistic Effect of a Minocycline/Lovastatin Combined Treatment on the Behavior of Individuals With Fragile X Syndrome; Validation of New Biochemical and Neurophysiological Markers (LovaMiX)Fragile X SyndromeDrug: Minocycline, then Minocycline/Lovastatin;Drug: Lovastatin, then Minocycline/LovastatinUniversité de SherbrookeFRAXA Research FoundationCompleted8 Years45 YearsAll22Phase 2Canada
2NCT02998151
(ClinicalTrials.gov)
January 20161/12/2016Single-Dose Acamprosate, Lovastatin, Minocycline and Placebo in Fragile X SyndromeEvaluating the Neurophysiologic and Clinical Effects of Single-Dose Acamprosate, Lovastatin, Minocycline and Placebo in Fragile X SyndromeFragile X SyndromeDrug: Acamprosate;Drug: Lovastatin;Drug: Minocycline;Drug: PlaceboChildren's Hospital Medical Center, CincinnatiEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Enrolling by invitation15 Years55 YearsAll36Phase 2United States
3NCT01053156
(ClinicalTrials.gov)
January 201019/1/2010Trial of Minocycline to Treat Children With Fragile X SyndromeRandomized Double-Blind Controlled Cross Over Trial of Minocycline in Children With Fragile X SyndromeFragile X SyndromeDrug: minocycline hydrochloride;Drug: PlaceboUniversity of California, DavisThe National Fragile X FoundationCompleted42 Months16 YearsAll66N/AUnited States
4NCT00858689
(ClinicalTrials.gov)
October 20079/3/2009Add-on Pilot Trial of Minocycline to Treat Fragile X SyndromeAdd-on Pilot Trial of Minocycline in Fragile X SyndromeFragile X SyndromeDrug: MinocyclineFRAXA Research FoundationFragile X Research Foundation of CanadaCompleted13 Years35 YearsAll20N/ACanada