DDrare: Database of Drug Development for Rare Diseases

Searched query = "Hypoplastic left heart syndrome", "HLHS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Allo-hMSCs; Ambrisentan; Autologous (self) mononuclear cells derived from umbilical cord blood; Autologous Human Placental Cord Blood Mononuclear Cells; Autologous Umbilical Cord Blood; Autologous cell-based delivery; Bosentan; C-kit+ cells; Curosurf; Erythropoetin; Longeveron Mesenchymal Stem Cells; METHYLPREDNISOLONE SODIUM SUCCINATE; MPC; Maternal Hyperoxygenation; Maternal hyperoxygenation; Methylprednisolone; Metyyliprednisoloninatriumsuksinaatti; Nitrogen; Normal saline; Oxandrolone; Procedure: Stage II Surgical repair; Rexlemestrocel-L; Sham; Sildenafil; Solu-Medrol; Solu-medrol; Tracleer; Vitamin C

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03431480 (ClinicalTrials.gov)	February 16, 2018	30/1/2018	Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery	Safety Study of Autologous Cord Blood Stem Cell Treatment in Hypoplastic Left Heart Syndrome Patients Undergoing the Norwood Heart Operation	Hypoplastic Left Heart Syndrome;Heart Defects, Congenital;Pediatric Disorder	Biological: Autologous Human Placental Cord Blood Mononuclear Cells	Murdoch Childrens Research Institute	NULL	Recruiting	N/A	4 Days	All	12	Phase 1	Australia

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NCT03431480
(ClinicalTrials.gov)

February 16, 2018

30/1/2018

Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery

Safety Study of Autologous Cord Blood Stem Cell Treatment in Hypoplastic Left Heart Syndrome Patients Undergoing the Norwood Heart Operation

Hypoplastic Left Heart Syndrome;Heart Defects, Congenital;Pediatric Disorder

Biological: Autologous Human Placental Cord Blood Mononuclear Cells

Murdoch Childrens Research Institute

NULL

Recruiting

N/A

4 Days

All

Phase 1

Australia