227. Osler disease
49 clinical trials,   69 drugs   (DrugBank: 21 drugs),   23 drug target genes,   132 drug target pathways

Searched query = "Osler disease", "Hereditary hemorrhagic telangiectasia", "Osler-Weber-Rendu disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
5 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2017-001031-39-FR
(EUCTR)
19/05/201719/06/2020BABH Study: Efficacy and safety of bevacizumab on severe bleedings associated with Hemorrhagic Hereditary Telangiectasia (HHT)BABH Study: Efficacy and safety of bevacizumab on severe bleedings associated with Hemorrhagic Hereditary Telangiectasia (HHT). A National, randomized multicenter phase III study. - BABH Hemorrhagic Hereditary Telangiectasia
MedDRA version: 20.0;Level: LLT;Classification code 10031132;Term: Osler-Weber-Rendu disease;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Trade Name: AVASTIN
Product Name: BEVACIZUMAB
INN or Proposed INN: BEVACIZUMAB
Hospices Civils de LyonNULLNot RecruitingFemale: yes
Male: yes
24Phase 3France
2EUCTR2013-004204-19-FR
(EUCTR)
26/02/201416/06/2015Efficacité du bevacizumab en spray nasal pour le traitement des épistaxis dans la maladie de Rendu-OslerEfficacité du bevacizumab en spray nasal pour le traitement des épistaxis dans la maladie de Rendu-Osler - ALEGORI Rendu-Osler disease
MedDRA version: 18.0;Level: LLT;Classification code 10031132;Term: Osler-Weber-Rendu disease;System Organ Class: 100000004850;Therapeutic area: Diseases [C] - Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Trade Name: Avastin
Product Name: Avastin
INN or Proposed INN: BEVACIZUMAB
Hospices Civils de LyonNULLNot RecruitingFemale: yes
Male: yes
France
3EUCTR2009-018049-19-AT
(EUCTR)
13/12/201023/11/2010A randomized double blind placebo controlled trial of intranasal submucosal bevacizumab in hereditary hemorrhagic telangiectasia - Bevazizumab in HHTA randomized double blind placebo controlled trial of intranasal submucosal bevacizumab in hereditary hemorrhagic telangiectasia - Bevazizumab in HHT epistaxisTrade Name: AVASTIN 25 mg/ml - Konzentrat zur Herstellung einer Infusionsloesung
INN or Proposed INN: BEVACIZUMAB
Trade Name: PHYSIOLOGISCHE Kochsalzloesung Fresenius - Infusionsloesung
Product Name: PHYSIOLOGISCHE Kochsalzloesung Fresenius - Infusionsloesung
Other descriptive name: SODIUM CHLORIDE
Medizinische Universität Wien,Univ.Klinik f.Hals-, Nasen- und OhrenkrankheitenNULLNot RecruitingFemale: yes
Male: yes
30Austria
4EUCTR2008-006755-44-FR
(EUCTR)
15/01/200917/03/2009METAFORE : Maladie de Rendu-Osler : Etude de l’Efficacité et de la tolérance du Bevacizumab utilisé pour le traitement des formes hépatiques sévères. Etude de phase II - METAFOREMETAFORE : Maladie de Rendu-Osler : Etude de l’Efficacité et de la tolérance du Bevacizumab utilisé pour le traitement des formes hépatiques sévères. Etude de phase II - METAFORE Maladie de Rendu-Osler
MedDRA version: 9.1;Level: LLT;Classification code 10031132;Term: Osler-Weber-Rendu disease
Trade Name: AVASTIN
Product Name: AVASTIN
INN or Proposed INN: BEVACIZUMAB
Other descriptive name: SUB16402MIG
HOSPICES CIVILS DE LYONNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
Phase 2France
5EUCTR2010-020545-26-IT
(EUCTR)
09/12/200810/09/2010BEVACIZUMAB, AN ANTI-ANGIOGENIC MONOCLONAL ANTIBODY EFFECTIVE FOR PREVENTION OF HEMORRHAGING IN PATIENTS WITH HEREDITARY HEMORRHAGIC TELANGIECTASIA (HHT): POSSIBLE REGRESSION OF VISCERAL ARTERIOVENOUS MALFORMATIONS - NDBEVACIZUMAB, AN ANTI-ANGIOGENIC MONOCLONAL ANTIBODY EFFECTIVE FOR PREVENTION OF HEMORRHAGING IN PATIENTS WITH HEREDITARY HEMORRHAGIC TELANGIECTASIA (HHT): POSSIBLE REGRESSION OF VISCERAL ARTERIOVENOUS MALFORMATIONS - ND HEREDITARY HEMORRHAGIC TELANGIECTASIA (HHT)
MedDRA version: 9.1;Level: SOC;Classification code 10005329
Trade Name: AVASTIN
INN or Proposed INN: Bevacizumab
Trade Name: AVASTIN
INN or Proposed INN: Bevacizumab
Trade Name: AVASTIN
INN or Proposed INN: Bevacizumab
AZIENDA OSPEDALIERA OSPEDALE POLICLINICO CONSORZIALENULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
Italy