331. Idiopathic multicentric castleman disease
30 clinical trials,   44 drugs   (DrugBank: 23 drugs),   30 drug target genes,   148 drug target pathways

Searched query = "Idiopathic multicentric castleman disease", "Castleman disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
3 trials found
No.TrialIDDate_
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PhaseCountries
1NCT01441063
(ClinicalTrials.gov)
September 13, 201124/9/2011Tocilizumab for KSHV-Associated Multicentric Castleman DiseasePilot Study of Tocilizumab in Patients With Symptomatic Kaposi Sarcoma Herpesvirus (KSHV) - Associated Multicentric Castleman DiseaseCastleman Disease;Multicentric Castleman Disease;Giant Lymph Node HyperplasiaDrug: Zidovudine;Drug: Tocilizumab;Drug: Valganciclovir (VGC)National Cancer Institute (NCI)NULLCompleted18 YearsN/AAll8Phase 2United States
2NCT00361933
(ClinicalTrials.gov)
December 20088/8/2006Valganciclovir to Treat HHV-8 Associated Multicentric Castleman's DiseaseClinical and Virologic Response to HHV-8 Associated Multicentric Castleman's Disease to ValganciclovirGiant Lymph Node HyperplasiaDrug: ValganciclovirUniversity of WashingtonHoffmann-La RocheWithdrawn18 YearsN/AAll0Phase 4United States
3NCT00092222
(ClinicalTrials.gov)
October 28, 200421/9/2004Virotherapy and Natural History Study of KHSV-Associated Multricentric Castleman s Disease With Correlates of Disease ActivityTargeted Oncolytic Virotherapy and Natural History Study of KSHV-Associated Multicentric Castleman's Disease With Laboratory and Clinical Correlates of Disease ActivityLymphoproliferative Disorder;HHV-8;Malignancy;HIVDrug: Etoposide;Drug: Interferon-alpha;Drug: Rituximab;Drug: Zidovudine;Drug: Liposomal Doxorubicin;Drug: Bortezomib;Drug: Valganciclovir;Drug: Doxorubicin;Drug: Vincristine;Drug: Cyclophosphamide;Drug: Filgrastim (G-CSF);Drug: Prednisone;Drug: Sirolimus;Other: Observation OnlyNational Cancer Institute (NCI)NULLRecruiting12 YearsN/AAll72Phase 2United States