40. Takayasu arteritis
22 clinical trials,   46 drugs   (DrugBank: 20 drugs),   22 drug target genes,   111 drug target pathways

Searched query = "Takayasu arteritis", "Aortitis syndrome", "Pulseless disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
10 trials found
No.TrialIDDate_
enrollment
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Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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agemin
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PhaseCountries
1NCT04564001
(ClinicalTrials.gov)
September 202021/9/2020Multicentre, Randomized, Prospective Trial Evaluating the Efficacy and Safety of Infliximab to Tocilizumab in Refractory or Relapsing Takayasu ArteritisMulticentre, Randomized, Prospective Trial Evaluating the Efficacy and Safety of Infliximab to Tocilizumab in Refractory or Relapsing Takayasu ArteritisTakayasu ArteritisDrug: Infliximab;Drug: TocilizumabAssistance Publique - Hôpitaux de ParisNULLNot yet recruiting18 YearsN/AAll50Phase 2NULL
2NCT04300686
(ClinicalTrials.gov)
March 1, 20205/3/2020A Pilot Study in Severe Patients With Takayasu Arteritis.A Pilot Study in the Treatment of Severe Patients With Takayasu Arteritis With Tocilizumab and Adalimumab, Based on ECTA CohortTakayasu Arteritis;Tocilizumab;Adalimumab;TreatmentBiological: Tocilizumab;Biological: AdalimumabShanghai Zhongshan HospitalNULLRecruiting14 Years100 YearsAll40Phase 4China
3EUCTR2018-003753-13-FR
(EUCTR)
19/03/201913/12/2018INTOReTAK : INfliximab and TOcilizumab in Refractory/relapsing TAKayasu arteritisMulticentre, randomized, prospective trial comparing the efficacy and safety of Infliximab to tocilizumab in refractory or relapsing Takayasu arteritis Patients with refractory or relapsing Takayasu Arteritis desease;Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02]Trade Name: RoActemra 20mg/ml
Product Name: Tocilizumab
INN or Proposed INN: Tocilizumab
Other descriptive name: TOCILIZUMAB
Product Name: Infliximab
INN or Proposed INN: INFLIXIMAB
ASSISTANCE PUBLIQUE - HOPITAUX DE PARISNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
50Phase 3France
4JPRN-UMIN000025940
2017/02/0707/02/2017Clinical Research on the Safety of anti-interleukin-6 antibody (Tocilizumab) treatment for the refractory patients with Takayasu ArteritisClinical Research on the Safety of anti-interleukin-6 antibody (Tocilizumab) treatment for the refractory patients with Takayasu Arteritis - TOCIlizumab treatment for TAKayasu arteritis (TOCI-TAK) Takayasu arteritisIntravenous administration of
tocilizumab (8mg/kg/month) for up to 12 months
Osaka UniversityNational Cerebral and Cardiovascular CenterComplete: follow-up continuing16years-old60years-oldMale and Female2Not selectedJapan
5NCT03893136
(ClinicalTrials.gov)
November 1, 201612/3/2019The Registry Study of Takayasu Arteritis in East ChinaThe Cohort Study of East Chinese Takayasu's Arteritis (ECTA-cohort Study)Takayasu Arteritis;Mechanisms, Defense;Pregnancy Related;Treatment Refusal;OutcomeBiological: Tocilizumab;Drug: LeflunomideShanghai Zhongshan HospitalNULLRecruiting18 Years65 YearsAll1000China
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
PhaseCountries
6JPRN-JapicCTI-142616
02/10/201423/07/2014Phase III Study of MRA-SC in Patients with Takayasu ArteritisA Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Phase III Study of MRA-SC in Patients with Takayasu Arteritis Takayasu ArteritisIntervention name : tocilizumab (MRA-SC)
INN of the intervention : tocilizumab
Dosage And administration of the intervention : 162mg/W, SC
Control intervention name : Placebo
INN of the control intervention : -
Dosage And administration of the control intervention : Placebo/W, SC
Chugai Pharmaceutical Co., Ltd.NULLcomplete12BOTH34Phase 3Japan
7JPRN-UMIN000025943
2014/08/0707/02/2017Long-term Safety of treatment with tocilizumab in the refractory patients with Takayasu ArteritisLong-term Safety of treatment with tocilizumab in the refractory patients with Takayasu Arteritis - Long-term ACTemra Investigation for remissION introduction in TAKayasu Arteritits (LACTION-TAK) Takayasu arteritisIntravenous administration of
tocilizumab (8mg/kg/month) will be performed until December 31st, 2017.
Osaka UnversityNational Cerebral and Cardiovascular CenterComplete: follow-up continuing16years-old60years-oldMale and Female9Not selectedJapan
8NCT02101333
(ClinicalTrials.gov)
June 10, 201417/2/2014Efficacy and Tolerance of Tocilizumab In Takayasu ArteritisEfficacy and Tolerance of First-line Treatment With Tocilizumab in Active Takayasu Arteritis French Prospective Multicenter StudyTAKAYASU ARTERITISDrug: TocilizumabAssistance Publique - Hôpitaux de ParisChugai PharmaceuticalCompleted18 Years77 YearsAll18Phase 3France
9JPRN-UMIN000008812
2012/10/0101/10/2012Efficacy and safety of tocilizumab mono-therapy in patients with large vessel vasculitis (LVV; giant cell arteritis or Takayasu arteritis) and polymyalgia rheumatica (PMR) Rheumatoid arthritistocilizumab monotherapyDepartment of Rheumatology & Clinical ImmunologySaitama Medical Center, Saitama Medical UniversitityNULLComplete: follow-up complete16years-old80years-oldMale and Female40Not selectedJapan
10JPRN-UMIN000007845
2012/05/0101/05/2012Efficacy and Safety of treatment with tocilizumab in refractory patients with Takayasu ArteritisEfficacy and Safety of treatment with tocilizumab in refractory patients with Takayasu Arteritis - ACTemra Investigation for remissiON introduction in Takayasu Arteritits (ACTION-TA) Takayasu arteritisIntravenous administration of tocilizumab (8mg/kg/month) for 24 monthsDepartment of Cardiovascular Medicine Graduate School of Medicine Osaka UniversityNULLComplete: follow-up continuing16years-old60years-oldMale and Female15Not selectedJapan