DDrare: Database of Drug Development for Rare Diseases

Searched query = "Giant cell arteritis", "Temporal arteritis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione; 18F-FDG; ABT-494; AIN457; ANAKINRA; Abatacept; Adalimumab; Alendronate; Alendronate versus alfacalcidol (1-alpha OH vitamin D); Alfacalcidol; Anakinra; Anti-thymocyte globulin; BOSENTAN MYLAN; Baricitinib; Blood samples; Bosentan; CNTO 136; CORTANCYL; Combination Product: mavrilimumab; Cortancyl; Cortancyl ® 1 mg; Cortancyl ® 20 mg; Cortancyl ® 5 mg; Corticoids+ tocilizumab 8mg/Kg/4 weeks; Corticosteroid (CS); Corticosteroids; Corticosteroids for Systemic Use; Cosentyx; Cyclophosphamide; Cyclosporine; Diagnostic Test: 68-Ga HA-DOTATATE PET/CT; Dotatate; Encorton; Filgrastim; GSK2973327; Gevokizumab; Glucocorticoid Treatment; Glucocorticoids; Guselkumab; Hydroxychloroquine; Infliximab; KINERET; KPL-301; Kevzara; Kevzara ®; Kineret; Lodotra; Lodotra (delayed release prednisolone); MAVRILIMUMAB; METOJECT; Mavrilimumab; Methotrexate; Methotrexate treatment; Methylprednisolone; Naltrexone; Naltrexone Hydrochloride; Nivolumab; Other: 18F-FDG PET/CT; Other: IV steroids combination alone; Other: Questionnaires; Other: questionnaires; Over encapsulated prednisone; PET10; PET3; PREDNISOLONE; PREDNISONE; Pr; PredniSONE Tablets USP, 1 mg; PredniSONE Tablets USP, 2.5 mg; PredniSONE Tablets USP, 5 mg; PredniSONE Tablets, USP; Prednisolon 1 mg JENAPHARM; Prednisolon 5 mg JENAPHARM; Prednisolone; Prednisolone 5 mg JENAPHARM; Prednisone; Prednisone Capsules; Prednisone Tablets, USP; Prednisone and ustekinumab treatment; Prednisone therapy and pharmacokinetic; Prednisone treatment; Procedure: Autologous Peripheral Blood Stem Cell Transplantation; Rituximab; Ro 001-9265; Ro 001-9265/F02; Ro 001-9265/F03; Ro 001-9265/F04; Ro 487-7533/F10-04; RoActemra; RoActemra 162 mg solution for injection in pre-filled syringe; S78989; SAR153191; SARILUMAB; SECUKINUMAB; Sarilumab; Sarilumab SAR153191; Secukinumab; Secukinumab 300 mg, s.c.; Sirukumab; TOCILIZUMAB; TOCILIZUMAB SC; Tocilizumab; Tocilizumab + Glucocorticoids (GCs); Tocilizumab SC; Tocilizumab and IV steroids combination; Tocilizumab treatment; Treatment; Upadacitinib; Ustekinumab; Vitamin D; XOMA 052

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03711448 (ClinicalTrials.gov)	January 7, 2019	15/10/2018	Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis	Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis	Patients Relapsing Refractory Giant Cell Arteritis	Drug: prednisone treatment;Drug: prednisone and ustekinumab treatment;Other: questionnaires;Biological: Blood samples	Centre Hospitalier Universitaire Dijon	NULL	Recruiting	50 Years	N/A	All	38	Phase 2	France
2	NCT02955147 (ClinicalTrials.gov)	December 1, 2016	31/10/2016	Ustekinumab for the Treatment of Giant Cell Arteritis	Open Label Study to Test the Safety and Efficacy of Ustekinumab in Patients With Giant Cell Arteritis	Giant Cell Arteritis;Temporal Arteritis;Horton's Disease	Drug: Ustekinumab;Drug: Prednisone	Massachusetts General Hospital	NULL	Terminated	50 Years	N/A	All	13	Phase 1;Phase 2	United States

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT03711448
(ClinicalTrials.gov)

January 7, 2019

15/10/2018

Ustekinumab for the Treatment of Relapse of Refractory Giant Cell Arteritis

Patients Relapsing Refractory Giant Cell Arteritis

Drug: prednisone treatment;Drug: prednisone and ustekinumab treatment;Other: questionnaires;Biological: Blood samples

Centre Hospitalier Universitaire Dijon

NULL

Recruiting

50 Years

N/A

All

Phase 2

France

NCT02955147
(ClinicalTrials.gov)

December 1, 2016

31/10/2016

Ustekinumab for the Treatment of Giant Cell Arteritis

Open Label Study to Test the Safety and Efficacy of Ustekinumab in Patients With Giant Cell Arteritis

Giant Cell Arteritis;Temporal Arteritis;Horton's Disease

Drug: Ustekinumab;Drug: Prednisone

Massachusetts General Hospital

NULL

Terminated

50 Years

N/A

All

Phase 1;Phase 2

United States