53. Sjogren syndrome
234 clinical trials, 270 drugs (DrugBank: 85 drugs), 49 drug target genes, 174 drug target pathways
Searched query = "Sjogren syndrome", "Sjögren syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT01759108 (ClinicalTrials.gov) | March 13, 2020 | 23/12/2012 | Rebamipide AND Sjögren Syndrome | Rebamipide for the Treatment of Xerostomia in Sjögren Syndrome | Improving Symptoms of Dry Mouth in Sjogren's Syndrome | Drug: Rebamipide | University of Alexandria | NULL | Recruiting | N/A | N/A | All | 55 | N/A | Egypt |
| 2 | NCT03608761 (ClinicalTrials.gov) | February 6, 2017 | 9/7/2018 | Comparison Between Rebamipide 2% Versus Autologous Serum | Comparison Between Rebamipide 2% Versus Autologous Serum in the Treatement of the Moderate to Severe Dry Eye Associate With Sjögren Syndrome. Pilot, Crossed, Controled, Randomized And Open Study | Dry Eye Syndromes;Sjögren Syndrome | Drug: Rebamipide;Biological: autologous serum;Other: autologous serum and rebamipide 2% | Hospital Nacional Profesor Alejandro Posadas | NULL | Completed | 18 Years | N/A | Female | 21 | Phase 4 | Argentina |
| 3 | JPRN-UMIN000013234 | 2014/04/01 | 01/04/2014 | Effect of the dual treatment of diquafosol sodium and rebamipide on dry eye syndrome related to chronic graft versus host disease and Sjogrens syndrome | Dry eye related to chronic GVHD and Sjogren s syndrome | Diquafosol sodium and rebamipide ophthalmic solution Artifical tears, vitamin A ophthalmic solution, or/and sodium hyaluronate ophthalmic solution | Keio University School of Medicine | NULL | Complete: follow-up complete | 20years-old | 75years-old | Male and Female | 20 | Not applicable | Japan | |
| 4 | JPRN-UMIN000010710 | 2013/05/15 | 15/05/2013 | Effective treatment of rebamipide on xerostomia in Sjogrens syndrome patients:a pilot study -a double-blind placebo-controlled trial- | Xerostomia in Sjogrens syndrome | Rebamipide was administered orally at 100 mg each time three times a day after meals for 8 weeks. Placebo was administered orally three times a day after meals for 8 weeks. | Tochigi medical center | NULL | Complete: follow-up complete | 20years-old | 80years-old | Male and Female | 60 | Phase 2 | Japan | |
| 5 | JPRN-UMIN000008427 | 2012/07/13 | 13/07/2012 | Evaluation of efficacy of rebamipide ophthalmic suspension in patients with dry eye associated with Sjogren's syndrome. | Patients with dry eye associated with Sjogren's syndrome. | Mucosta ophthalmic suspension UD2% | Kanazawa Medical University | NULL | Complete: follow-up complete | 20years-old | Not applicable | Male and Female | 30 | Not selected | Japan | |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | NCT00233363 (ClinicalTrials.gov) | March 2005 | 4/10/2005 | Exploratory Study for Dry Mouth in Patients With Sjögren’s Syndrome | An Exploratory Study of Rebamipide to Evaluate Efficacy and Safety in the Treatment of Dry Mouth in Patients With Sjögren’s Syndrome | Xerostomia;Sjogren's Syndrome | Drug: Rebamipide | Otsuka Pharmaceutical Co., Ltd. | NULL | Completed | 20 Years | N/A | Both | 100 | Phase 2 | Japan |
| 7 | JPRN-JapicCTI-050036 | 06/09/2005 | Exploratory study of rebamipide to evaluate the efficacy and safety in treatment of dry mouth in patients with Sjogren's syndrome | Exploratory study of rebamipide to evaluate the efficacy and safety in treatment of dry mouth in patients with Sjogren's syndrome | Dry mouth in patients with Sjogren's syndrome | Intervention name : Rebamipide Dosage And administration of the intervention : Oral | Otsuka Pharmaceutical Co., Ltd. | NULL | 20 | BOTH | Phase 2 | NULL |