DDrare: Database of Drug Development for Rare Diseases

Searched query = "Addison disease", "Primary chronic adrenocortical insufficiency", "Autoimmune polyglandular syndrome", "Hypoparathyroidism-Addison-Monilia syndrome", "HAM syndrome", "Schmidt syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Drug = Acetate; Cortef; Cortef (hydrocortisone); Cortef 5 mg; Cosyntropin; Dehydroepiandrosterone; Depot tetracosactide; Device: 30-hour ambulatory sampling of intestinal fluid; Dexamethasone; Diagnostic Test: Baseline blood tests; Diagnostic Test: Cosyntropin stimulation test; Grapefruit; Grapefruit Juice; HYDROCORTISONE HYDROGEN SUCCINATE; HYDROCORTISONE ROUSSEL; HYDROCORTISONE SODIUM SUCCINATE; Hydrocortison 100 mg (Pfizer®) in 2 ml solvent; Hydrocortisone; Hydrocortisone 100mg/ml; Hydrocortisone Roussel; Hydrocortisone hydrogen succinate; Hydrocortisone sodium phosphate; Hydrocortisonum; Hydrogen; Hydrokortison APL kapsel 2,5 mg; Isocaloric Diet; Liquorice; MabThera; Mabthera Infusion; Mabthera infusion; Medrone; Methylprednisolone; Phosphate; Rituximab; Solu-Cortef; Solu-Cortef (hydrocortisone); Solu-Medrone; Solu-cortef; Solu-medrone; Synacthen Depot; Tetracosactide; Tetracosactide acetate

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2009-010917-61-SE (EUCTR)	25/08/2010	05/07/2010	Glucocorticoid Replacement in Addison's disease	Glucocorticoid Replacement in Addison's disease	Autoimmune Addison's disease is a rare and chronic disease wich leads to primary adrenal failure. The conventional glucocorticoid replacement therapy in primary adrenal insufficiency (Addison’s disease) renders the cortisol levels unphysiological, which may cause symptoms and long-term complications. In this study we will include patients with Addison's disease to explore if more physiological glucocorticoid treatment could improve health for the patients. MedDRA version: 9.1;Level: LLT;Classification code 10001130;Term: Addison's disease	Trade Name: Solu-Cortef INN or Proposed INN: HYDROCORTISONE SODIUM SUCCINATE Product Name: Hydrokortison APL kapsel 2,5 mg INN or Proposed INN: Hydrocortisonum	Haukeland University hospital	NULL	Not Recruiting			Female: yes Male: yes	40		Sweden

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EUCTR2009-010917-61-SE
(EUCTR)

25/08/2010

05/07/2010

Glucocorticoid Replacement in Addison's disease

Autoimmune Addison's disease is a rare and chronic disease wich leads to primary adrenal failure. The conventional glucocorticoid replacement therapy in primary adrenal insufficiency (Addison’s disease) renders the cortisol levels unphysiological, which may cause symptoms and long-term complications. In this study we will include patients with Addison's disease to explore if more physiological glucocorticoid treatment could improve health for the patients.
MedDRA version: 9.1;Level: LLT;Classification code 10001130;Term: Addison's disease

Trade Name: Solu-Cortef
INN or Proposed INN: HYDROCORTISONE SODIUM SUCCINATE
Product Name: Hydrokortison APL kapsel 2,5 mg
INN or Proposed INN: Hydrocortisonum

Haukeland University hospital

NULL

Not Recruiting

Female: yes
Male: yes

Sweden