86. Pulmonary arterial hypertension
1,083 clinical trials,   667 drugs   (DrugBank: 122 drugs),   98 drug target genes,   185 drug target pathways

Searched query = "Pulmonary arterial hypertension", "PAH", "IPAH", "HPAH", "Eisenmenger syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
2 trials found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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PhaseCountries
1EUCTR2005-004863-41-DE
(EUCTR)
04/10/200625/07/2006Clinical investigation into efficacy, hemodynamics and tolerability of simvastatin vs placebo in patients with pulmonary arterial hypertension(Shorttitle: SIPHT)Double-blind, randomized, prospective Phase III-b study for 6 months with adjusting doses of simvastatin (40/80 mg daily) or placebo followed by an open-label period with a final dose of simvastatin 80 mg daily for another 6 months - SIPHTClinical investigation into efficacy, hemodynamics and tolerability of simvastatin vs placebo in patients with pulmonary arterial hypertension(Shorttitle: SIPHT)Double-blind, randomized, prospective Phase III-b study for 6 months with adjusting doses of simvastatin (40/80 mg daily) or placebo followed by an open-label period with a final dose of simvastatin 80 mg daily for another 6 months - SIPHT Modified NYHA class II or III patients with Pulmonary Hypertension (PH), ICD: 416.9
MedDRA version: 8.1;Level: LLT;Classification code 10020787;Term: Hypertension pulmonary
Trade Name: simvastatin 40 mg tablets
Product Name: simvastatin
Product Name: simvastatin 40 mg
Product Code: simvastatin 40 mg
INN or Proposed INN: simvastatin
Dept. of Internal Medicine II, University Hospital GiessenNULLNot RecruitingFemale: yes
Male: yes
40Phase 3-bGermany
2NCT00384865
(ClinicalTrials.gov)
September 200630/9/2006A Study of Aspirin and Simvastatin in Pulmonary Arterial HypertensionA Clinical Trial of Aspirin and Simvastatin in Pulmonary Arterial HypertensionHypertension, PulmonaryDrug: Simvastatin;Drug: Aspirin;Drug: PlaceboUniversity of PennsylvaniaNational Heart, Lung, and Blood Institute (NHLBI)Terminated18 YearsN/AAll64Phase 2United States