94. Primary sclerosing cholangitis
134 clinical trials,   105 drugs   (DrugBank: 37 drugs),   18 drug target genes,   131 drug target pathways

Searched query = "Primary sclerosing cholangitis", "PSC"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
3 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1EUCTR2015-003392-30-NL
(EUCTR)
02/05/201617/12/2015The testing of NGM282 for 12 weeks in patients with Primary Sclerosing Cholangitis (PSC)A PHASE 2, RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED, PARALLEL GROUP, MULTIPLE CENTER STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND EFFICACY OF NGM282 ADMINISTERED FOR 12 WEEKS IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS (PSC) PRIMARY SCLEROSING CHOLANGITIS (PSC)
MedDRA version: 19.0;Level: LLT;Classification code 10036732;Term: Primary sclerosing cholangitis;System Organ Class: 10019805 - Hepatobiliary disorders
MedDRA version: 19.0;Level: HLT;Classification code 10004607;Term: Bile duct infections and inflammations;Level: SOC;Classification code 10019805;Term: Hepatobiliary disorders;Level: PT;Classification code 10008609;Term: Cholangitis sclerosing;Level: HLGT;Classification code 10004606;Term: Bile duct disorders;System Organ Class: 10019805 - Hepatobiliary disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: NGM282
INN or Proposed INN: engineered recombinant human FGF19
Other descriptive name: rec-h-FGF19
Product Name: NGM282
INN or Proposed INN: engineered recombinant human FGF19
Other descriptive name: rec-h-FGF19
NGM Biopharmaceuticals, Inc.NULLNot RecruitingFemale: yes
Male: yes
60Phase 2France;United States;Netherlands;United Kingdom
2EUCTR2015-003392-30-GB
(EUCTR)
18/04/201614/12/2015The testing of NGM282 for 12 weeks in patients with Primary Sclerosing Cholangitis (PSC)A PHASE 2, RANDOMIZED, DOUBLE BLIND, PLACEBO CONTROLLED, PARALLEL GROUP, MULTIPLE CENTER STUDY TO EVALUATE THE SAFETY, TOLERABILITY, AND EFFICACY OF NGM282 ADMINISTERED FOR 12 WEEKS IN PATIENTS WITH PRIMARY SCLEROSING CHOLANGITIS (PSC) PRIMARY SCLEROSING CHOLANGITIS (PSC)
MedDRA version: 19.0;Level: LLT;Classification code 10036732;Term: Primary sclerosing cholangitis;System Organ Class: 10019805 - Hepatobiliary disorders
MedDRA version: 19.0;Level: HLT;Classification code 10004607;Term: Bile duct infections and inflammations;Level: SOC;Classification code 10019805;Term: Hepatobiliary disorders;Level: PT;Classification code 10008609;Term: Cholangitis sclerosing;Level: HLGT;Classification code 10004606;Term: Bile duct disorders;System Organ Class: 10019805 - Hepatobiliary disorders ;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
NGM Biopharmaceuticals, Inc.NULLNot Recruiting Female: yes
Male: yes
60Phase 2France;United States;Netherlands;United Kingdom
3NCT02704364
(ClinicalTrials.gov)
March 201629/2/2016Phase 2 Study of NGM282 in Patients With Primary Sclerosing CholangitisA Phase 2, Randomized, Double Blind, Placebo Controlled, Parallel Group, Multiple Center Study to Evaluate the Safety, Tolerability, and Efficacy of NGM282 Administered for 12 Weeks in Patients With Primary Sclerosing CholangitisPrimary Sclerosing CholangitisBiological: NGM282;Other: PlaceboNGM Biopharmaceuticals, IncNULLCompleted18 Years75 YearsAll62Phase 2United States;France;Netherlands;United Kingdom