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96. Crohn disease
2,209 clinical trials,   1,276 drugs   (DrugBank: 240 drugs),   166 drug target genes,   210 drug target pathways

Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
18 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT04331639
(ClinicalTrials.gov)		September 202023/3/2020High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic TherapyImplementation of High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Infliximab or VedolizumabInflammatory Bowel Disease;Crohn Disease;Ulcerative Colitis;Vitamin D DeficiencyDietary Supplement: vitamin D3Boston Children's HospitalNULLNot yet recruiting5 Years25 YearsAll50Phase 2NULL
2NCT04225819
(ClinicalTrials.gov)		April 1, 20203/1/2020Adjunctive Treatment With Vitamin D3 in Patients With Active IBDAdjunctive Treatment With Vitamin D3 in Patients With Active IBD (ACTIVATED): A Randomized, Double-blind, Placebo-controlled TrialIBD;Inflammatory Bowel Diseases;Crohn Disease;Ulcerative Colitis;Vitamin D3 DeficiencyDietary Supplement: Vitamin D3;Other: PlaceboMassachusetts General HospitalNULLNot yet recruiting18 YearsN/AAll100N/ANULL
3NCT03999580
(ClinicalTrials.gov)		February 7, 202024/6/2019The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )A Pragmatic Randomized Controlled Trial on High Dose Vitamin D to Prevent Relapses of Crohn's Disease in ChildrenCrohn DiseaseDrug: vitamin D3Jantchou PrevostNULLRecruiting4 Years18 YearsAll316Phase 3Canada
4NCT03718182
(ClinicalTrials.gov)		September 17, 201923/10/2018Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy?Can Vitamin D Supplementation in People With Crohn's Disease Improve Symptoms as an Adjunct Therapy? D-CODE Feasibility Randomised Controlled TrialCrohn Disease;Vitamin D DeficiencyDietary Supplement: CholecalciferolUniversity Hospital Birmingham NHS Foundation TrustNational Institute for Health Research, United Kingdom;University of Birmingham;Clinical Trials Research CentreRecruiting18 YearsN/AAll50Phase 4United Kingdom
5NCT03162432
(ClinicalTrials.gov)		August 1, 201715/5/2017High Dose Interval Vitamin D Supplementation in Patients With IBD Receiving RemicadeHigh Dose Interval Vitamin D Supplementation in Patients With IBD Receiving RemicadeIBD;Ulcerative Colitis;Crohn DiseaseDrug: Vitamin D3Boston Children's HospitalNULLCompleted7 Years25 YearsAll50Phase 3United States
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
6NCT02186275
(ClinicalTrials.gov)		February 20164/7/2014The Vitamin D in Pediatric Crohn's DiseaseRandomized Controlled Trial of High Dose Vitamin D in Children With Newly Diagnosed Crohn's Disease for the Prevention of RelapsesCrohn's DiseaseDrug: Vitamin D3: 3000 or 4000 UI/day then 2,000 UI/day;Drug: Vitamin D3 800 UI/day then 800 UI/daySt. Justine's HospitalCanadian Institutes of Health Research (CIHR)Completed9 Years18 YearsAll25Phase 3Canada
7NCT02208310
(ClinicalTrials.gov)		April 20151/8/2014Trial of High Dose Vitamin D in Patient's With Crohn's DiseaseA Randomized Controlled Trial of High-Dose Vitamin D in Crohn's DiseaseCrohn's Disease;Vitamin D DeficiencyDrug: Cholecalciferol 10,000 IU;Drug: Cholecalciferol 400 IUUniversity of MichiganCrohn's and Colitis FoundationTerminated18 Years75 YearsAll11Phase 4United States
8EUCTR2013-002838-20-BE
(EUCTR)		09/12/201415/09/2014The effect of Vitamin D to prevent post-operative relapse of Crohn's DiseaseThe effect of Vitamin D3 to prevent post-operative relapse of Crohn’s Disease: a placebo-controlled randomized trial (DETECT) - DETECT Crohn's Disease
MedDRA version: 19.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]		Trade Name: D-CURA
Product Name: D-Cura
INN or Proposed INN: Cholecalciferol
Other descriptive name: CHOLECALCIFEROL CONCENTRATE (WATER-DISPERSIBLE FORM)		Academic Medical CenterNULLNot RecruitingFemale: yes
Male: yes		142Phase 3Belgium;Netherlands
9NCT02615288
(ClinicalTrials.gov)		January 201423/11/2015High Dose Vitamin D3 in Crohn's DiseaseImpact of High Dose Vitamin D3 Supplementation in Treatment of Crohn's Disease in Remission: A Randomized Double-blind Controlled StudyCrohn's DiseaseDietary Supplement: Vitamin D3McMaster UniversityCanadian Association of GastroenterologyCompleted18 Years70 YearsBoth40N/ANULL
10EUCTR2013-002838-20-NL
(EUCTR)		12/11/201306/09/2013The effect of Vitamin D to prevent post-operative relapse of Crohn's DiseaseThe effect of Vitamin D3 to prevent post-operative relapse of Crohn’s Disease: a placebo-controlled randomized trial (DETECT) - DETECT Crohn's Disease
MedDRA version: 18.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]		Trade Name: InVita D3
INN or Proposed INN: Colecalciferol
Other descriptive name: CHOLECALCIFEROL CONCENTRATE 		Academic Medical CenterNULLNot RecruitingFemale: yes
Male: yes		142Phase 3Belgium;Netherlands
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
11NCT01864616
(ClinicalTrials.gov)		July 201322/5/2013The Impact of Vitamin D on Disease Activity in Crohn's DiseaseCrohn DiseaseDietary Supplement: Vitamin D3University of SaskatchewanDania Alrefai;Dr.Jennifer Jones;Dr.Hani Jawa;Dr.Wael El-matary;Saudi Arabian Cultural BureauTerminated16 Years70 YearsAll9N/ACanada;Saudi Arabia
12NCT02010762
(ClinicalTrials.gov)		February 201310/12/2013The Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's DiseaseThe Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's Disease: a Placebo-controlled Randomized TrialCrohn's DiseaseDrug: Vitamin D;Drug: PlaceboAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NULLCompleted18 YearsN/AAll142Phase 4Netherlands
13NCT01692808
(ClinicalTrials.gov)		October 201217/9/2012Bioavailability of Vitamin D in Children and Adolescents With Crohn's DiseaseBioavailability of Vitamin D in Children and Adolescents With Crohn's Disease.Crohn's DiseaseDrug: Vitamin D3 3000 UI daily;Drug: Vitamin D3 4000 UI dailySt. Justine's HospitalNULLCompleted10 Years18 YearsBoth20Phase 2Canada
14NCT01369667
(ClinicalTrials.gov)		April 20127/6/2011Vitamin D Supplementation in Adult Crohn's DiseaseVitamin D and Immunomodulation: Effects in Crohn's DiseaseCrohn's DiseaseDietary Supplement: Vitamin D3;Other: PlaceboUniversity of Dublin, Trinity CollegeQueen Mary University of LondonCompleted18 Years75 YearsBoth117Phase 4Ireland
15NCT01877577
(ClinicalTrials.gov)		April 201211/6/2013Supplementation of Vitamin D3 in Patients With Inflammatory Bowel Diseases and Hypovitaminosis DSupplementation of Vitamin D3 (Cholecalciferol) in Patients With Inflammatory Bowel Diseases (IBD) and Hypovitaminosis D: A Prospective Randomized Controlled Trial.Crohn's Disease (CD);Ulcerative Colitis (UC)Dietary Supplement: Vitamin D3University of California, San FranciscoNULLCompleted18 YearsN/ABoth30N/AUnited States
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
16NCT01046773
(ClinicalTrials.gov)		January 201011/1/2010Vitamin D Supplementation as Non-toxic Immunomodulation in Children With Crohn's DiseaseVitamin D Supplementation as Non-toxic Immunomodulation in Children With Crohn's DiseaseCrohn's Disease;Vitamin D DeficiencyDrug: CholecalciferolUniversity of California, Los AngelesThe Broad FoundationTerminated8 Years18 YearsAll3Phase 1United States
17NCT00672763
(ClinicalTrials.gov)		May 20082/5/2008Adjuvant Vitamin D With Corticosteroids in Active Crohn's DiseaseThe Immunomodulatory Role of Vitamin D in Inflammatory Bowel Disease (The IBDVit Study): Double-Blind, Placebo-Controlled Trial of Adjuvant Vitamin D (Colecalciferol) With Corticosteroids in Active Crohn's DiseaseCrohn's DiseaseDrug: Colecalciferol D3 (Vigantol Oil);Drug: Medium chain triglyceridesImperial College LondonNULLWithdrawn18 YearsN/ABoth0Phase 4United Kingdom
18NCT00621257
(ClinicalTrials.gov)		January 200811/2/2008Vitamin D Levels in Children With IBDOptimization of Vitamin D Stores and Its Impact on the Bone Health and Disease Outcomes of Children and Adolescents With IBD.Inflammatory Bowel Disease;Crohn's Disease;Ulcerative ColitisDietary Supplement: ergocalciferol;Dietary Supplement: CholecalciferolBoston Children’s HospitalNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);Crohn's and Colitis Foundation;NASPGHAN FoundationTerminated5 Years21 YearsAll134N/AUnited States

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