96. Crohn disease
2,209 clinical trials,   1,276 drugs   (DrugBank: 240 drugs),   166 drug target genes,   210 drug target pathways

Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
21 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
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Status
Inclusion_
agemin
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agemax
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PhaseCountries
1NCT04223518
(ClinicalTrials.gov)
September 20, 20206/1/2020Serum Bovine Immunoglobulin (SBI) in Children and Young Adults With Inflammatory Bowel Disease (IBD)Safety, Tolerability, and Nutritional Impact of Serum Bovine Immunoglobulin (SBI) in Children and Young Adults With Inflammatory Bowel DiseaseInflammatory Bowel Diseases;Ulcerative Colitis;Crohn DiseaseDietary Supplement: Serum bovine immunoglobulin;Dietary Supplement: PlaceboMonisha Hitesh ShahNULLRecruiting6 Years30 YearsAll43Early Phase 1United States
2NCT04273399
(ClinicalTrials.gov)
March 20208/1/2020High-impact Exercise in Adults With Crohn's DiseaseFeasibility of High-impact Exercise to Improve Musculoskeletal Outcomes in Adults With Crohn's DiseaseCrohn DiseaseOther: High-impact exercise intervention;Other: Acute response to high-impact exerciseNHS Greater Glasgow and ClydeUniversity of GlasgowNot yet recruiting18 Years40 YearsAll30N/AUnited Kingdom
3NCT04305535
(ClinicalTrials.gov)
February 13, 20205/3/2020Impact of an Oligomeric Diet in Intestinal Absorption and Inflammatory Markers in Patients With Crohn DiseaseClinical Trial to Evaluate the Effect of an Oligomeric Oral Nutritional Supplement on the Response in Intestinal Absorption and Inflammation, in Patients With CROHN DiseaseCrohn Disease;Absorption; Disorder, Protein; Disorder; Disorder, Fat; Disorder, Carbohydrate;MalnutritionDietary Supplement: Peptidic+Probiotic;Dietary Supplement: Peptidic+Placebo;Dietary Supplement: Polymeric+PlaceboInstituto de Investigación Sanitaria de la Fundación Jiménez DíazAdventia Pharma, S.L.;Biopolis S.L.Recruiting18 YearsN/AAll162N/ASpain
4NCT03941418
(ClinicalTrials.gov)
June 1, 20195/5/2019Impact of Additional Treatment With Saccharomyces Boulardii on Quality of Life in Patients With Mild Forms of Ulcerative Colitis and Crohn DiseaseImpact of Additional Treatment With Saccharomyces Boulardii on Quality of Life in Patients With Mild Forms of Ulcerative Colitis and Crohn DiseaseUlcerative Colitis;Crohn DiseaseDietary Supplement: Boulardii;Dietary Supplement: PlaceboUniversity Clinic Dr Dragisa Misovic-DedinjeUniversity Clinic ZvezdaraNot yet recruiting18 Years80 YearsAll150N/ANULL
5NCT03012542
(ClinicalTrials.gov)
January 20174/1/2017Diet as Essential Therapy (DIET) for Inflammatory Bowel DiseaseRandomized Trial of Diet for Crohn's Disease and Impact on Disease Activity and the MicrobiomeCrohn DiseaseDietary Supplement: Diet 1;Dietary Supplement: Diet 2University of WashingtonNULLUnknown status18 YearsN/AAll32N/AUnited States
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6NCT02704624
(ClinicalTrials.gov)
December 201624/2/2016Effects of Supplementation of Vitamin D in Patients With Crohn's DiseaseThe Impact of Serum Vitamin D and Calcium Levels on the Body Composition, Bone Mineral Density, Muscle Strength, Exercise Tolerance, Fatigue and Inflammatory Activity in Patients With Crohn's Disease: a Randomized Controlled TrialCrohn Disease;Vitamin D Deficiency;Fatigue;Sarcopenia;Muscle Weakness;Disorder of Bone Density and Structure, UnspecifiedDietary Supplement: Vitamin D;Other: PlaceboFederal University of Juiz de ForaFundação de Amparo à Pesquisa do estado de Minas GeraisEnrolling by invitation18 Years50 YearsAll110Phase 4Brazil
7NCT02750800
(ClinicalTrials.gov)
April 7, 201613/4/2016Post-marketing Observational Study to Evaluate the Incremental Impact of AbbVie's Patient Support Program on Patient Reported Outcomes and Health Resource Utilization in Inflammatory Arthritis, Psoriasis and Inflammatory Bowel Diseases in Hungary (VALUE)Post-marketing Observational Study to Evaluate the Effect of HUMIRA (Adalimumab) Treatment With AbbVie's Patient Support Program on Patient Reported Outcomes and Health Resource Utilization in Inflammatory Arthritis, Psoriasis and Inflammatory Bowel Diseases in Hungary in a Real-life Setting: VALUERheumatoid Arthritis;Ankylosing Spondylitis;Psoriatic Arthritis;Psoriasis;Crohn's Disease;Ulcerative ColitisBiological: Adalimumab;Behavioral: AbbVie Care 2.0AbbVieNULLCompleted18 Years99 YearsAll427Hungary
8NCT02742597
(ClinicalTrials.gov)
January 12, 201621/3/2016Patient-Centred Innovations for Persons With Multimorbidity - OntarioPatient-Centred Innovations for Persons With Multimorbidity - OntarioHypertension;Depression;Anxiety;Musculoskeletal Pain;Arthritis;Rheumatoid Arthritis;Osteoporosis;Chronic Obstructive Pulmonary Disease (COPD);Asthma;Chronic Bronchitis;Cardiovascular Disease;Heart Failure;Stroke;Transient Ischemic Attacks;Ulcer;Gastroesophageal Reflux;Irritable Bowel;Crohn's Disease;Ulcerative Colitis;Diverticulosis;Chronic Hepatitis;Diabetes;Thyroid Disorder;Cancer;Kidney Disease;Urinary Tract Problem;Dementia;Alzheimer's Disease;Hyperlipidemia;HIV;MultimorbidityBehavioral: TIP / IMPACT Plus Care CoordinationLawson Health Research InstituteWestern University, Canada;Université de Sherbrooke;Canadian Institutes of Health Research (CIHR);Sunnybrook Health Sciences Centre;St. Michael's Hospital, Toronto;University Health Network, Toronto;Toronto East General Hospital;Providence HealthCare;Mount Sinai Hospital, Canada;Toronto Central Community Care Access Centre;Women's College HospitalActive, not recruiting18 Years80 YearsAll1980N/ACanada
9NCT02575040
(ClinicalTrials.gov)
May 20156/10/2015Efficacy of Fecal Microbiota Transplantation for Inflammatory Bowel DiseaseEfficacy of Fecal Microbiota Transplantation for Refractory Inflammatory Bowel DiseaseUlcerative Colitis;Crohn Disease;Constipation (Excl Faecal Impaction)Biological: Fecal microbiota transplantationGulhane Military Medical AcademyNULLRecruiting18 YearsN/ABoth60Phase 3Turkey
10NCT02453607
(ClinicalTrials.gov)
November 17, 201421/5/2015The Impact of 6MP Metabolite Levels on Infliximab Pharmacokinetics and Anti-infliximab Antibodies in Crohn's DiseaseThe Impact of 6MP Metabolite Levels on Infliximab Pharmacokinetics and Anti-infliximab Antibodies in Crohn's DiseaseInflammatory Bowel Disease;Crohn's DiseaseDrug: Infliximab;Drug: thiopurineErnest SeidmanUniversity of Toronto;University of Calgary;University of AlbertaRecruiting18 Years70 YearsAll225N/ACanada
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
11NCT02426567
(ClinicalTrials.gov)
November 201417/4/2015The Impact of Crohn's Disease-TReatment-with-EATing Diet and Exclusive Enteral Nutrition on Healthy Gut BacteriaAn Exploratory Study on the Impact of a Food-based Restrictive Diet (Crohn's Disease-TReatment-with EATing/CD-TREAT Diet) and Liquid Exclusive Enteral Nutrition (EEN) on Healthy Gut Microbiota Composition and Metabolic ActivityCrohn's Disease;Dietary ModificationOther: Exclusive Enteral Nutrition (EEN);Other: Crohn's Disease TReatment-with-EATing diet (CD-TREAT diet)University of GlasgowNULLCompleted18 YearsN/ABoth28N/AUnited Kingdom
12NCT02615288
(ClinicalTrials.gov)
January 201423/11/2015High Dose Vitamin D3 in Crohn's DiseaseImpact of High Dose Vitamin D3 Supplementation in Treatment of Crohn's Disease in Remission: A Randomized Double-blind Controlled StudyCrohn's DiseaseDietary Supplement: Vitamin D3McMaster UniversityCanadian Association of GastroenterologyCompleted18 Years70 YearsBoth40N/ANULL
13NCT01864616
(ClinicalTrials.gov)
July 201322/5/2013The Impact of Vitamin D on Disease Activity in Crohn's DiseaseCrohn DiseaseDietary Supplement: Vitamin D3University of SaskatchewanDania Alrefai;Dr.Jennifer Jones;Dr.Hani Jawa;Dr.Wael El-matary;Saudi Arabian Cultural BureauTerminated16 Years70 YearsAll9N/ACanada;Saudi Arabia
14NCT01847170
(ClinicalTrials.gov)
May 20132/5/2013Impact of Fecal Biotherapy (FBT) on Microbial Diversity in Patients With Moderate to Severe Inflammatory Bowel DiseaseCrohn's DiseaseBiological: Fecal Microbial TransplantationBeth Israel Deaconess Medical CenterThe Broad Foundation;Brigham and Women's HospitalCompleted18 YearsN/AAll22Phase 1United States
15NCT02233062
(ClinicalTrials.gov)
May 20131/9/2014Impact of Exclusive Enteral Nutrition Therapy on Sperm Quality of Patients With Crohn's DiseaseImpact of Exclusive Enteral Nutrition Therapy on Sperm Quality of Male Patients With Crohn's DiseaseCrohn's DiseaseDietary Supplement: Exclusive Enteral Nutrition TherapyJinling Hospital, ChinaNULLCompleted18 Years40 YearsMale12N/AChina
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
16NCT01218360
(ClinicalTrials.gov)
November 20117/10/2010Observational Study of Disease Severity in Participants Diagnosed With Crohn's Disease and Long Term Impact of Treatment Strategies in Participants With Moderate to Severe Crohn's Disease (Protocol P06484)Observational Study on Disease Severity, Evaluation Tools and the Long Term Impact of Each Treatment Strategy in the Daily Clinical Practice in Patients With Moderate to Severe Active Crohn's Disease (Protocol P06484)Crohn DiseaseDrug: Physician standard-of-careMerck Sharp & Dohme Corp.NULLCompleted18 Years65 YearsBoth71N/AGreece
17NCT01540942
(ClinicalTrials.gov)
November 201123/2/2012Impact of Disease Activity and Nutrition Treat on Postoperative Recurrence and Complications After Bowel Resection for Crohn's DiseaseA Randomized, Controlled, Open-label Study to Investigate the Impact of Disease Activity and Nutrition Treat on Postoperative Recurrence and Complications After Bowel Resection for Crohn's DiseaseCrohn's DiseaseDietary Supplement: nutrition treat;Other: surgeryJinling Hospital, ChinaNULLCompleted18 Years75 YearsBoth91N/AChina
18NCT02619552
(ClinicalTrials.gov)
August 201128/10/2015Impact of Medical Treatment on Sexual Function in Patients With Crohn's DiseaseImpact of Medical Treatment on Sexual Function in Patients With Crohn's DiseaseCrohn's Disease;IBDDrug: Anti-TNF;Drug: SteroidsUniversity of Maryland, BaltimoreVanderbilt University;Milton S. Hershey Medical Center;Mercy Medical CenterCompleted18 YearsN/AAll50United States
19NCT01487759
(ClinicalTrials.gov)
March 20086/12/2011Prebiotic Effect on Metabolites in Crohn's DiseaseMetabolite Profiling of the Impact of Oligofructose Enriched Inulin in Crohn's Disease PatientsCrohn DiseaseDietary Supplement: Oligofructose enriched inulin;Dietary Supplement: MaltodextrinKatholieke Universiteit LeuvenNULLCompleted18 YearsN/ABoth67N/ABelgium
20NCT00621257
(ClinicalTrials.gov)
January 200811/2/2008Vitamin D Levels in Children With IBDOptimization of Vitamin D Stores and Its Impact on the Bone Health and Disease Outcomes of Children and Adolescents With IBD.Inflammatory Bowel Disease;Crohn's Disease;Ulcerative ColitisDietary Supplement: ergocalciferol;Dietary Supplement: CholecalciferolBoston Children’s HospitalNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK);Crohn's and Colitis Foundation;NASPGHAN FoundationTerminated5 Years21 YearsAll134N/AUnited States
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
21NCT00705471
(ClinicalTrials.gov)
April 200523/6/2008Impact of Infliximab in Fistulizing Crohn's Disease on Health Care Resources (Study P04204)(TERMINATED)Infliximab Use in Fistulizing Crohn's Disease: Impact on Health Care ResourcesCrohn DiseaseBiological: InfliximabMerck Sharp & Dohme Corp.Centocor, Inc.Terminated18 YearsN/ABoth42N/ANULL