Ketamine (DrugBank: Ketamine)
5 diseases| 告示番号 | 疾患名（ページ内リンク） | 臨床試験数 |
|---|---|---|
| 13 | 多発性硬化症／視神経脊髄炎 | 1 |
| 70 | 広範脊柱管狭窄症 | 4 |
| 113 | 筋ジストロフィー | 1 |
| 156 | レット症候群 | 1 |
| 215 | ファロー四徴症 | 1 |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03500289 (ClinicalTrials.gov) | August 10, 2018 | 4/4/2018 | Ketamine for Treatment of MS Fatigue | Ketamine for Treatment of Multiple Sclerosis-related Fatigue | Multiple Sclerosis;Fatigue | Drug: Ketamine;Drug: Midazolam | Johns Hopkins University | National Multiple Sclerosis Society | Completed | 18 Years | 65 Years | All | 18 | Phase 1;Phase 2 | United States |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03088306 (ClinicalTrials.gov) | July 1, 2017 | 22/2/2017 | Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients | Comparative Effectiveness of Multi-modal Pain Management Versus Standard Intra- and Post-operative Analgesia: Randomized Controlled Clinical Trial to Reduce Post-operative Pain and Opioid Use Among Patients Undergoing Lumbar Spine Surgery | Lumbar Spinal Stenosis;Lumbar Spinal Instability;Lumbar Spine Degeneration | Drug: Standard analgesia use [Oxygen];Drug: Standard analgesia use [Hydromorphone];Drug: Standard analgesia use [Volatile Anesthesia];Drug: Standard analgesia use [Fentanyl];Drug: Multi-modal pain management [Acetaminophen + Gabapentin];Drug: Multi-modal pain management [Fentanyl];Drug: Multi-modal pain management [Intravenous Ketamine];Drug: Multi-modal pain management [Valium + Gabapentin] | Johns Hopkins University | North American Spine Society | Completed | 18 Years | 100 Years | All | 49 | Early Phase 1 | United States |
| 2 | EUCTR2016-002887-14-FI (EUCTR) | 31/10/2016 | 14/10/2016 | Dose-response of ketamine in patient controlled analgesia in orthopaedic surgery patients | Dose response study of Patient Controlled Analgesia (PCA) of S-ketamine in orthopaedic spine surgery patients - DoseRespKeta | Patients who are scheduled for elective posterolateral lumbar spine fusion with bilateral transpedicular screw instrumentation MedDRA version: 19.0;Level: LLT;Classification code 10041595;Term: Spinal stenosis lumbar;System Organ Class: 100000004859;Therapeutic area: Body processes [G] - Bones and nerves physological processes [G11] | Trade Name: Ketanest-S INN or Proposed INN: KETAMINE Trade Name: Oxycodone Orion INN or Proposed INN: OXYCODONE | University of Turku | NULL | Not Recruiting | Female: yes Male: yes | 100 | Phase 1;Phase 4 | Finland | ||
| 3 | EUCTR2012-000747-26-FI (EUCTR) | 27/04/2012 | 02/04/2012 | Ketamine to reduce postoperative pain in back surgery | Administration of S-Ketamine during spinal surgery to reduce postoperative pain | adult patients undergoing spinal surgery MedDRA version: 14.1;Level: LLT;Classification code 10041595;Term: Spinal stenosis lumbar;System Organ Class: 10028395 - Musculoskeletal and connective tissue disorders ;Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03] | Helsinki Universiy Central Hospital | NULL | Not Recruiting | Female: yes Male: yes | 192 | Phase 4 | Finland | |||
| 4 | NCT01275547 (ClinicalTrials.gov) | January 2011 | 11/1/2011 | The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam | The Analgesic Effect of Combined Treatment With Intranasal S-Ketamine and Intranasal Midazolam Compared With Morphine Patient Controlled Analgesia in Spinal Surgery Patients | Analgesia, Patient-controlled;Spinal Stenosis | Drug: s-ketamine & midazolam;Drug: Morphine PCA | University Hospital, Basel, Switzerland | NULL | Completed | 18 Years | N/A | Both | 22 | Phase 2;Phase 3 | Switzerland |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT01645098 (ClinicalTrials.gov) | August 2011 | 8/6/2012 | Sedation During Muscle Biopsy in Patients With Duchenne Muscular Dystrophy | Sedation During Muscle Biopsy in Patients With Duchenne Muscular Dystrophy | Duchenne Muscular Dystrophy | Drug: Ketamine;Drug: Dexmedetomidine | Nationwide Children's Hospital | NULL | Completed | N/A | N/A | Male | 53 | N/A | United States |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03633058 (ClinicalTrials.gov) | March 12, 2019 | 8/8/2018 | A Study to Evaluate Ketamine for the Treatment of Rett Syndrome | A Randomized, Double-blind, Placebo-controlled, Cross-over Study to Assess the Safety, Tolerability and Efficacy of Oral Ketamine for Patients With Rett Syndrome | Rett Syndrome | Drug: Ketamine | Rett Syndrome Research Trust | Vanderbilt University Medical Center | Recruiting | 6 Years | 12 Years | Female | 48 | Phase 2 | United States |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ChiCTR-IOR-16008571 | 2016-06-06 | 2016-05-31 | Premedication for children with Tetralogy of Fallot | A comparative evalution of varies premedication regimes on children with Tetralogy of Fallot | Tetralogy of Fallot | oral dexmedetomidine:oral dexmedetomidine;oral ketamine:oral ketamine;oral dexmedetomidine mixed with ketamine:oral dexmedetomidine mixed with ketamine; | Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University | NULL | Recruiting | Both | oral dexmedetomidine:20;oral ketamine:20;oral dexmedetomidine mixed with ketamine:20; | China |