DDrare: Database of Drug Development for Rare Diseases

Metoprolol succinate + doxazosin (DrugBank: Metoprolol, Doxazosin)

6 diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
17	多系統萎縮症	0
57	特発性拡張型心筋症	1
58	肥大型心筋症	0
113	筋ジストロフィー	0
193	プラダー・ウィリ症候群	0
226	間質性膀胱炎（ハンナ型）	0

17. 多系統萎縮症　［臨床試験数：107，薬物数：153（DrugBank：48），標的遺伝子数：59，標的パスウェイ数：104］

Searched query = "Multiple system atrophy", "MSA-C", "MSA-P", "Olivopontocerebellar atrophy", "OPCA", "Striatonigral degeneration", "Shy-Drager syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 107 trial found

57. 特発性拡張型心筋症　［臨床試験数：12，薬物数：25（DrugBank：12），標的遺伝子数：9，標的パスウェイ数：33］

Searched query = "Idiopathic dilated cardiomyopathy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 12 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01798992 (ClinicalTrials.gov)	September 2000	22/2/2013	Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human Heart	Beta-blocker Effect on Structural Remodeling and Gene Expression in the Failing Human Heart	Idiopathic Dilated Cardiomyopathy	Drug: Carvedilol;Drug: Metoprolol succinate;Drug: Metoprolol succinate + doxazosin	University of Colorado, Denver	National Heart, Lung, and Blood Institute (NHLBI);GlaxoSmithKline;AstraZeneca	Completed	18 Years	N/A	All	56	Phase 4	United States

58. 肥大型心筋症　［臨床試験数：92，薬物数：126（DrugBank：35），標的遺伝子数：40，標的パスウェイ数：141］

Searched query = "Hypertrophic cardiomyopathy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 92 trial found

113. 筋ジストロフィー　［臨床試験数：567，薬物数：442（DrugBank：93），標的遺伝子数：55，標的パスウェイ数：151］

Searched query = "Muscular dystrophy", "Dystrophinopathies", "Myotilinopathy", "Laminopathy", "Caveolinopathy", "LGMD1C", "Desminopathy", "Sarcoglycanopathy", "α-dystroglycanopathy", "FCMD", "Walker-Warburg syndrome", "Muscle-eye-brain disease", "Myotonic dystrophy", "Integrin α7 deficient CMD", "Rigid spine syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 567 trial found

193. プラダー・ウィリ症候群　［臨床試験数：95，薬物数：104（DrugBank：27），標的遺伝子数：50，標的パスウェイ数：63］

Searched query = "Prader-Willi syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 95 trial found

226. 間質性膀胱炎（ハンナ型）　［臨床試験数：133，薬物数：151（DrugBank：46），標的遺伝子数：48，標的パスウェイ数：137］

Searched query = "Interstitial cystitis with Hunners ulcer", "Interstitial cystitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 133 trial found