Acetohydroxamic acid    (DrugBank: Acetohydroxamic acid)

1 disease
告示番号疾患名(ページ内リンク)臨床試験数
251尿素サイクル異常症2

251. 尿素サイクル異常症 [臨床試験数:42,薬物数:45(DrugBank:10),標的遺伝子数:4,標的パスウェイ数:29
Searched query = "Urea cycle disorder", "N-acetylglutamate synthase deficiency", "NAGS deficiency", "Carbamoyl phosphate synthetase I deficiency", "CPS1 deficiency", "Ornithine transcarbamylase deficiency", "OTC deficiency", "Classic citrullinemia", "Citrullinemia type I", "Argininosuccinic aciduria", "Argininemia", "Hiperornitinemia-hiperamonemia-homocitrulinuria syndrome", "HHH syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 42 trials found
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PhaseCountries
1NCT03181828
(ClinicalTrials.gov)
March 24, 20171/6/2017Manipulating the Gut Microbiome StudyManipulating the Gut Microbiome StudyUrea Cycle DisorderDrug: Acetohydroxamic Acid Oral Tablet [Lithostat]Nicholas Ah MewNULLTerminated18 Years60 YearsAll4Phase 1;Phase 2United States
2NCT02670889
(ClinicalTrials.gov)
November 201614/1/2016Urease Inhibitor Drug Treatment for Urea Cycle DisordersManipulating the Gut Microbiome in Urea Cycle DisordersOrnithine Transcarbamylase Deficiency;Argininosuccinate Synthetase Deficiency (Citrullinemia);Argininosuccinic Acid Lyase Deficiency (Argininosuccinic Aciduria);Carbamyl-Phosphate Synthase I DeficiencyDrug: Acetohydroxamic Acid;Drug: Isotopic Intravenous [13C]-UreaNicholas Ah MewData Management and Coordinating Center (DMCC);Children's Hospital of PhiladelphiaNot yet recruiting18 Years60 YearsBoth16Phase 1;Phase 2NULL