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Pentoxifylline    (DrugBank: Pentoxifylline)

10 diseases
告示番号疾患名（ページ内リンク）臨床試験数
26HTLV-1関連脊髄症1
56ベーチェット病2
84サルコイドーシス1
93原発性胆汁性胆管炎［原発性胆汁性肝硬変 (~2017.3)］1
96クローン病1
113筋ジストロフィー2
220急速進行性糸球体腎炎1
222一次性ネフローゼ症候群1
296胆道閉鎖症1
298遺伝性膵炎1

26. HTLV-1関連脊髄症　［臨床試験数：26，薬物数：46（DrugBank：27），標的遺伝子数：37，標的パスウェイ数：123］
Searched query = "HTLV-1-associated myelopathy", "Tropical spastic paraparesis", "HTLV-1", "HTLV-I-associated myelopathy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 26 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT01472263
(ClinicalTrials.gov)		September 200911/11/2011Use of Pentoxifylline in Human T-lymphotropic Virus Type-1 (HTLV-1) DiseasesEffectiveness of Pentoxifylline in Attenuating Neurological Disease Associated With HTLV-1 and Negative Modulator of Pathological Immune Response.HTLV-1;Tropical Spastic Paraparesis;Immune System Diseases;Physical Disability;PentoxifyllineDrug: Pentoxifylline;Drug: PlaceboHospital Universitário Professor Edgard SantosNULLCompleted18 Years80 YearsBoth48Phase 3Brazil

56. ベーチェット病　［臨床試験数：68，薬物数：87（DrugBank：31），標的遺伝子数：36，標的パスウェイ数：113］
Searched query = "Behcet disease", "Behçet disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 68 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT04186559
(ClinicalTrials.gov)		February 20202/12/2019Topical Pentoxifylline Gel on Behcet's Disease Genital UlcersClinical Protocol to Evaluate Use of Topical Pentoxifylline Gel on Behcet's Disease Genital UlcersBehcet Syndrome;Behcet DiseaseDrug: Topical Pentoxifylline Gel (Vehicle +PTX);Drug: Topical Placebo Gel (Vehicle)Silk Road Therapies, Inc.NULLNot yet recruiting18 YearsN/AAll60Phase 2United States
2NCT03888846
(ClinicalTrials.gov)		March 25, 201921/3/2019Topical Pentoxifylline Gel on Behcet's Disease Oral UlcersClinical Protocol for Administration of Topical Pentoxifylline Gel on Behcet's Disease Oral UlcersBehçet Disease Affecting Oral MucosaDrug: Pentoxifylline;Drug: ColchicineIpekyolu Ilac Ltd. StiIstanbul University-Cerrahpasa School of MedicineRecruiting18 YearsN/AAll60Phase 2Turkey

84. サルコイドーシス　［臨床試験数：143，薬物数：221（DrugBank：79），標的遺伝子数：82，標的パスウェイ数：165］
Searched query = "Sarcoidosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 143 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00001877
(ClinicalTrials.gov)		February 19993/11/1999Treatment of Pulmonary Sarcoidosis With PentoxifyllineTreatment of Pulmonary Sarcoidosis With PentoxifyllinePulmonary SarcoidosisDrug: PentoxifyllineNational Heart, Lung, and Blood Institute (NHLBI)NULLCompletedN/AN/ABoth100Phase 2United States

93. 原発性胆汁性胆管炎［原発性胆汁性肝硬変 (~2017.3)］　［臨床試験数：230，薬物数：215（DrugBank：51），標的遺伝子数：34，標的パスウェイ数：107］
Searched query = "Primary biliary cholangitis", "Primary biliary cirrhosis", "PBC"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 230 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT01249092
(ClinicalTrials.gov)		November 201024/11/2010Pentoxifylline for Primary Biliary CirrhosisA Pilot Study of Pentoxifylline for the Treatment of Primary Biliary CirrhosisPrimary Biliary CirrhosisDrug: PentoxifyllineThe Cleveland ClinicNULLCompleted18 Years76 YearsAll20Phase 2United States

96. クローン病　［臨床試験数：2,209，薬物数：1,276（DrugBank：240），標的遺伝子数：166，標的パスウェイ数：210］
Searched query = "Crohn disease", "Terminal ileitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 2,209 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT02953275
(ClinicalTrials.gov)		April 13, 201731/10/2016Synergistic Effect of Vedolizumab and PentoxifyllineSynergistic Effect of Vedolizumab and Pentoxifylline in the Management of Patients With Inflammatory Bowel DiseaseCrohn DiseaseDrug: vedolizumab;Drug: Pentoxifylline;Drug: placeboUniversity of MiamiTakedaCompleted18 Years80 YearsAll37Early Phase 1United States

113. 筋ジストロフィー　［臨床試験数：567，薬物数：442（DrugBank：93），標的遺伝子数：55，標的パスウェイ数：151］
Searched query = "Muscular dystrophy", "Dystrophinopathies", "Myotilinopathy", "Laminopathy", "Caveolinopathy", "LGMD1C", "Desminopathy", "Sarcoglycanopathy", "α-dystroglycanopathy", "FCMD", "Walker-Warburg syndrome", "Muscle-eye-brain disease", "Myotonic dystrophy", "Integrin α7 deficient CMD", "Rigid spine syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
2 / 567 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00243789
(ClinicalTrials.gov)		September 200521/10/2005Study of Daily Pentoxifylline as a Rescue Treatment in Duchenne Muscular DystrophyA Double-Blinded Randomized Placebo Controlled Study of Daily Pentoxifylline as a Rescue Treatment in DMDMuscular Dystrophy, DuchenneDrug: PentoxifyllineCooperative International Neuromuscular Research GroupNULLCompleted7 YearsN/AMale64Phase 1;Phase 2United States;Argentina;Australia;Canada;Israel;Italy
2NCT00102453
(ClinicalTrials.gov)		March 200229/1/2005Pentoxifylline in Duchenne Muscular DystrophyAn Open-Label Pilot Study of Pentoxifylline in Steroid-naive Duchenne Muscular DystrophyMuscular Dystrophy, DuchenneDrug: PentoxifyllineCooperative International Neuromuscular Research GroupNULLCompleted4 Years7 YearsMale17Phase 1;Phase 2United States

220. 急速進行性糸球体腎炎　［臨床試験数：2，薬物数：5（DrugBank：2），標的遺伝子数：1，標的パスウェイ数：1］
Searched query = "Rapidly progressive glomerulonephritis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 2 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00354198
(ClinicalTrials.gov)		August 200618/7/2006Efficacy of Pentoxifylline on Rapidly Progressive GlomerulonephritisClinical Efficacy of Combined Pentoxifylline and Conventional Immunosuppressive Regimens on Patients With Rapidly Progressive GlomerulonephritisGlomerulonephritisDrug: pentoxifylline;Drug: corticosteroidsNational Taiwan University HospitalNational Science Council, TaiwanTerminated20 Years80 YearsBoth7Phase 3Taiwan

222. 一次性ネフローゼ症候群　［臨床試験数：234，薬物数：241（DrugBank：78），標的遺伝子数：59，標的パスウェイ数：185］
Searched query = "Primary nephrotic syndrome", "Minimal change nephrotic syndrome", "MCNS", "Membranous nephropathy", "Focal segmental glomerulosclerosis", "FSGS", "Membranoproliferative glomerulonephritis", "MPGN"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 234 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT00354731
(ClinicalTrials.gov)		August 200618/7/2006Efficacy of Pentoxifylline on Primary Nephrotic SyndromeClinical Efficacy of Pentoxifylline on Patients With Primary Nephrotic SyndromeNephrotic SyndromeDrug: pentoxifylline;Drug: CorticosteroidNational Taiwan University HospitalNational Science Council, TaiwanCompleted20 Years80 YearsBoth62Phase 3Taiwan

296. 胆道閉鎖症　［臨床試験数：53，薬物数：56（DrugBank：31），標的遺伝子数：43，標的パスウェイ数：50］
Searched query = "Biliary atresia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 53 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT01774487
(ClinicalTrials.gov)		January 201322/1/2013Pentoxifylline Therapy in Biliary AtresiaA Phase II Trial of Pentoxifylline in Newly-Diagnosed Biliary AtresiaBiliary AtresiaDrug: PentoxifyllineBaylor College of MedicineNULLRecruitingN/A180 DaysAll60Phase 2United States

298. 遺伝性膵炎　［臨床試験数：93，薬物数：168（DrugBank：51），標的遺伝子数：48，標的パスウェイ数：134］
Searched query = "Hereditary pancreatitis", "Chronic pancreatitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 93 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT02487225
(ClinicalTrials.gov)		May 201529/6/2015Pentoxifylline Treatment in Acute Pancreatitis (AP)Pentoxifylline Treatment in Acute Pancreatitis: A Double-Blind Placebo - Controlled Randomized TrialAcute Pancreatitis (AP);Gallstone Pancreatitis;Alcoholic Pancreatitis;Trauma Acute Pancreatitis;Hypertriglyceridemia Acute Pancreatitis;Idiopathic (Unknown) Acute Pancreatitis;Medication Induced Acute Pancreatitis;Cancer Acute Pancreatitis;Miscellaneous (i.e. Acute on Chronic Pancreatitis)Drug: Pentoxifylline;Drug: PlaceboMayo ClinicNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Completed18 Years100 YearsAll83Phase 3United States

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