Hyperpolarized xenon    (DrugBank: Xenon)

1 disease
告示番号疾患名(ページ内リンク)臨床試験数
299嚢胞性線維症6

299. 嚢胞性線維症 [臨床試験数:1,592,薬物数:1,539(DrugBank:255),標的遺伝子数:81,標的パスウェイ数:162
Searched query = "Cystic fibrosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
6 / 1,592 trials found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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agemax
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PhaseCountries
1NCT04467957
(ClinicalTrials.gov)
October 1, 202019/6/2020Non-contrast Lung Perfusion Mapping Applied for New Insights in Cystic FibrosisNon-contrast Lung Perfusion Mapping Applied for New Insights in Cystic FibrosisCystic FibrosisDrug: Initiation of CFTR Modulator;Drug: Hyperpolarized Xenon 129Children's Hospital Medical Center, CincinnatiNULLNot yet recruiting6 Years21 YearsAll26Phase 4NULL
2NCT03593434
(ClinicalTrials.gov)
July 30, 201828/6/2018Airway Clearance Therapy on Hyperpolarized 129Xenon and MRIThe Effect of Airway Clearance Therapy on Hyperpolarized 129Xenon MRI Compared With Lung Clearance Index and Spirometry in Cystic FibrosisCystic FibrosisDrug: hyperpolarized Xenon gasChildren's Hospital Medical Center, CincinnatiNational Heart, Lung, and Blood Institute (NHLBI)Recruiting6 Years21 YearsAll20United States
3NCT03482960
(ClinicalTrials.gov)
May 29, 201823/3/2018Comparison of 129Xe MRI With 19F MRI in CF Lung DiseaseComparison of 129Xe MRI With 19F MRI in CF Lung DiseaseCystic FibrosisDrug: Hyperpolarized Xenon gas;Drug: PFPUniversity of North Carolina, Chapel HillCystic Fibrosis FoundationCompleted18 YearsN/AAll15Early Phase 1United States
4NCT02912637
(ClinicalTrials.gov)
October 201613/9/2016Hyperpolarized Xenon Imaging in Patients With Cystic FibrosisHyperpolarised 129Xe MRI for Non-invasive Assessment of Ventilation, Perfusion and the Alveolar Membrane - a Physiological Study in Healthy Volunteers & Cystic Fibrosis PatientsCystic FibrosisOther: Hyperpolarized Xenon MRIPapworth Hospital NHS Foundation TrustUniversity of SheffieldSuspended18 Years70 YearsAll30United Kingdom
5NCT02848560
(ClinicalTrials.gov)
March 201626/7/2016Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRIValidation of MRI as a Sensitive Tool to Longitudinally Monitor CF Lung Disease Progression and Response to CFTR Modulator Therapy in Young Children With CFCystic FibrosisDrug: Hyperpolarized XenonChildren's Hospital Medical Center, CincinnatiNational Heart, Lung, and Blood Institute (NHLBI)Recruiting6 Years12 YearsAll38United States
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6NCT02740868
(ClinicalTrials.gov)
August 201519/8/2015Xenon-129 Lung Magnetic Resonance Imaging: Study of Healthy Volunteers and Participants With Pulmonary DiseaseDevelopment of Hyperpolarized Xenon-129 Lung Magnetic Resonance Imaging: Comparative Pilot Study of Healthy Volunteers and Participants With Pulmonary DiseaseCystic Fibrosis;AsthmaDrug: Xenon-129;Device: Magnetic Resonance Imaging;Device: Lung Clearance IndexThe Hospital for Sick ChildrenNULLRecruiting8 YearsN/AAll30Phase 2Canada