DDrare: Database of Drug Development for Rare Diseases

Col7a1-sin retroviral vector engineered autologous tissue-engineered skin (DrugBank: -)

告示番号	疾患名（ページ内リンク）	臨床試験数
36	表皮水疱症	1

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04186650 (ClinicalTrials.gov)	January 10, 2020	25/11/2019	Ex Vivo Gene Therapy Clinical Trial for RDEB Using Genetically Corrected Autologous Skin Equivalent Grafts	Phase I/II ex Vivo Gene Therapy Clinical Trial for RDEB Using Autologous Skin Equivalent Grafts Genetically Corrected With a COL7A1-encoding SIN Retroviral Vector	Epidermolysis Bullosa Dystrophica, Recessive	Biological: COL7A1-SIN retroviral vector engineered autologous tissue-engineered skin	Institut National de la Santé Et de la Recherche Médicale, France	NULL	Enrolling by invitation	18 Years	N/A	All	3	Phase 1;Phase 2	France

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT04186650
(ClinicalTrials.gov)

January 10, 2020

25/11/2019

Ex Vivo Gene Therapy Clinical Trial for RDEB Using Genetically Corrected Autologous Skin Equivalent Grafts

Phase I/II ex Vivo Gene Therapy Clinical Trial for RDEB Using Autologous Skin Equivalent Grafts Genetically Corrected With a COL7A1-encoding SIN Retroviral Vector

Epidermolysis Bullosa Dystrophica, Recessive

Biological: COL7A1-SIN retroviral vector engineered autologous tissue-engineered skin

Institut National de la Santé Et de la Recherche Médicale, France

NULL

Enrolling by invitation

18 Years

N/A

All

Phase 1;Phase 2

France