Mra(tocilizumab) (DrugBank: Tocilizumab)
2 diseases| 告示番号 | 疾患名（ページ内リンク） | 臨床試験数 |
|---|---|---|
| 46 | 悪性関節リウマチ | 7 |
| 107 | 若年性特発性関節炎［全身型若年性特発性関節炎（~2018.3）］ | 3 |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT00380601 (ClinicalTrials.gov) | May 2006 | 25/9/2006 | Phase?Open-label Study of MRA for Rheumatoid Arthritis(RA) | An Open-label, Phase? Study to Evaluate the Efficacy and Safety of MRA in Patients With RA | Rheumatoid Arthritis | Drug: MRA(Tocilizumab) | Chugai Pharmaceutical | NULL | Completed | 20 Years | N/A | Both | 20 | Phase 3 | Japan |
| 2 | NCT00144586 (ClinicalTrials.gov) | March 2005 | 2/9/2005 | Long-term Treatment Study of MRA for Rheumatoid Arthritis (RA) From Study MRA220JP or MRA221JP | An Open-label, Extension, Phase III Study to Evaluate the Long-term Safety and Efficacy of MRA in Patients With RA Who Participated in Study MRA220JP or MRA221JP | Rheumatoid Arthritis | Drug: MRA(Tocilizumab) | Chugai Pharmaceutical | NULL | Completed | 20 Years | 75 Years | Both | 42 | Phase 3 | NULL |
| 3 | NCT00144560 (ClinicalTrials.gov) | February 2005 | 2/9/2005 | Drug-Drug Interaction Study of MRA in Patient With Rheumatoid Arthritis (RA) | An Open-Label, Clinical Pharmacology Study to Investigate Drug-Drug Interaction in Patients With RA | Rheumatoid Arthritis | Drug: MRA(Tocilizumab) | Chugai Pharmaceutical | NULL | Completed | 20 Years | 75 Years | Both | 31 | N/A | NULL |
| 4 | NCT00144573 (ClinicalTrials.gov) | January 2005 | 2/9/2005 | Clinical Pharmacology Study of MRA in Patient With Rheumatoid Arthritis (RA) With Renal Impairment | An Open-Label, Clinical Pharmacology Study to Evaluate the Safety and PK of MRA in Patients With RA With Renal Impairment | Rheumatoid Arthritis | Drug: MRA(Tocilizumab) | Chugai Pharmaceutical | NULL | Completed | 20 Years | 75 Years | Both | 14 | N/A | NULL |
| 5 | NCT00144547 (ClinicalTrials.gov) | April 2004 | 2/9/2005 | Long-term Treatment Study of MRA for Rheumatoid Arthritis (RA) From Study MRA012JP | An Open-label, Extension, Phase III Study to Evaluate the Long-term Safety and Efficacy of MRA in Patients With RA Who Participated in Study MRA012JP | Rheumatoid Arthritis | Drug: MRA(Tocilizumab) | Chugai Pharmaceutical | NULL | Completed | 20 Years | N/A | Both | 241 | Phase 3 | NULL |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
| 6 | NCT00144521 (ClinicalTrials.gov) | February 2004 | 2/9/2005 | Comparative Study (Double-Blind) of MRA for Rheumatoid Arthritis (RA) | A Double-Blind, Phase III Study to Evaluate the Efficacy and Safety of MRA in Patients With RA | Rheumatoid Arthritis | Drug: MRA(Tocilizumab);Drug: MRA placebo;Drug: MTX;Drug: MTX placebo | Chugai Pharmaceutical | NULL | Completed | 20 Years | 75 Years | Both | 127 | Phase 3 | NULL |
| 7 | NCT00144651 (ClinicalTrials.gov) | August 2001 | 2/9/2005 | Study of MRA in Patients With Rheumatoid Arthritis (RA) | An Open-label, Extension, Phase II Study to Evaluate the Long-term Safety and Efficacy of MRA in Patients With RA Who Were Participated in Study MRA009JP | Rheumatoid Arthritis | Drug: MRA(Tocilizumab) | Chugai Pharmaceutical | NULL | Completed | 20 Years | N/A | Both | 135 | Phase 2 | NULL |
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT00144664 (ClinicalTrials.gov) | November 2004 | 2/9/2005 | Study of MRA for Polyarticular Juvenile Idiopathic Arthritis (pJIA) | An Open-Label, Phase III Study to Evaluate the Efficacy, Safety and PK of MRA in Patients With pJIA | Systemic Juvenile Idiopathic Arthritis | Drug: MRA(Tocilizumab) | Chugai Pharmaceutical | NULL | Completed | 2 Years | 19 Years | Both | 19 | Phase 3 | NULL |
| 2 | NCT00144612 (ClinicalTrials.gov) | July 2004 | 2/9/2005 | Long-term Treatment Study of MRA for Systemic Juvenile Idiopathic Arthritis (sJIA) | An Open-label, Extension, Phase III Study to Evaluate the Long-term Safety and Efficacy of MRA in Patients With sJIA Who Participated in Studies MRA011JP or MRA316JP | Systemic Juvenile Idiopathic Arthritis | Drug: MRA(Tocilizumab) | Chugai Pharmaceutical | NULL | Completed | 2 Years | 19 Years | Both | 60 | Phase 3 | NULL |
| 3 | NCT00144599 (ClinicalTrials.gov) | May 2004 | 2/9/2005 | Study of MRA for Systemic Juvenile Idiopathic Arthritis (sJIA) | A Double-Blind, Phase III Study to Evaluate the Efficacy, Safety and PK of MRA in Patients With sJIA | Systemic Juvenile Idiopathic Arthritis | Drug: MRA(Tocilizumab);Drug: placebo | Chugai Pharmaceutical | NULL | Completed | 2 Years | 19 Years | Both | 56 | Phase 3 | NULL |