DDrare: Database of Drug Development for Rare Diseases

告示番号	疾患名（ページ内リンク）	臨床試験数
46	悪性関節リウマチ	1

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03649061 (ClinicalTrials.gov)	June 8, 2018	30/7/2018	COBRA-Slim With or Without Fast Access to TNF Blockade for Remission Induction in Early RA	Effectiveness of a Combination of Methotrexate and a Step Down Glucocorticoid Regimen (COBRA-Slim) for Remission Induction in Patients With Early Rheumatoid Arthritis (RA), With or Without Fast Access to 24 Weeks of Tumor Necrosis Factor (TNF) Blockade in Insufficient Responders, a Randomized, Multicenter, Pragmatic Trial	Arthritis, Rheumatoid	Drug: Etanercept 50 MG/ML;Drug: Leflunomide 10 milligram (MG)	P. Verschueren	Belgium Health Care Knowledge Centre	Active, not recruiting	18 Years	N/A	All	284	Phase 4	Belgium

No.

TrialID

Date_
enrollment

Date_
registration

Public_title

Scientific_title

Condition

Intervention

Primary_
sponsor

Secondary_
sponsor

Recruitment_
Status

Inclusion_
agemin

Inclusion_
agemax

Inclusion_
gender

Target_
size

Phase

Countries

NCT03649061
(ClinicalTrials.gov)

June 8, 2018

30/7/2018

COBRA-Slim With or Without Fast Access to TNF Blockade for Remission Induction in Early RA

Effectiveness of a Combination of Methotrexate and a Step Down Glucocorticoid Regimen (COBRA-Slim) for Remission Induction in Patients With Early Rheumatoid Arthritis (RA), With or Without Fast Access to 24 Weeks of Tumor Necrosis Factor (TNF) Blockade in Insufficient Responders, a Randomized, Multicenter, Pragmatic Trial

Arthritis, Rheumatoid

Drug: Etanercept 50 MG/ML;Drug: Leflunomide 10 milligram (MG)

P. Verschueren

Belgium Health Care Knowledge Centre

Active, not recruiting

18 Years

N/A

All

284

Phase 4

Belgium