Tso    (DrugBank: -)

3 diseases
IDDisease name (Link within this page)Number of trials
13Multiple sclerosis/Neuromyelitis optica3
46Malignant rheumatoid arthritis1
97Ulcerative colitis3

13. Multiple sclerosis/Neuromyelitis optica    [ 3,050 clinical trials,   2,147 drugs,   (DrugBank: 348 drugs),   244 drug target genes,   228 drug target pathways]
Searched query = "Multiple sclerosis/Neuromyelitis optica", "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 3,050 trials found
No.TrialIDDate_
enrollment
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Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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agemin
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PhaseCountries
1NCT01413243
(ClinicalTrials.gov)
September 20128/8/2011Trichuris Suis Ova (TSO)in Recurrent Remittent Multiple Sclerosis and Clinically Isolated SyndromeTrichuris Suis Ova (TSO)in Recurrent Remittent Multiple Sclerosis and Clinically Isolated Syndrome - A Monocentric, Prospective, Randomized, Double-blind and Placebo-controlled Phase 2 TrialMultiple SclerosisDrug: Trichuris suis ovaCharite University, Berlin, GermanyNULLTerminated18 Years65 YearsBoth50Phase 2Germany
2EUCTR2009-015319-41-DE
(EUCTR)
03/11/201104/02/2011Trichuris suis Oozyten (TSO®) in remittent-recurrent Multiple Sclerosis (MS) and Clinically Isolated Syndrom (CIS)Trichuris suis Oozyten (TSO®) in remittent-recurrent Multiple Sclerosis (MS) and Clinically Isolated Syndrom (CIS) - TRIOMS remittent-recurrent Multiple Sclerosis (MS) and Clinically Isolated Syndrom (CIS);Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Therapeutic techniques [E02]Product Name: TSO
Product Code: TSO
INN or Proposed INN: Trichuris suis ova (eggs), embryonated, viable
Charite Universitätsmedizin BerlinNULLNot RecruitingFemale: yes
Male: yes
Phase 2Germany
3EUCTR2008-007549-29-DK
(EUCTR)
09/06/200906/05/2009Trichuris suis Ova Therapy for Relapsing Multiple Sclerosis - a safety study - TRIMS ATrichuris suis Ova Therapy for Relapsing Multiple Sclerosis - a safety study - TRIMS A Relapsing Multipel Sclerosis
MedDRA version: 12.0;Level: LLT;Classification code 10028245;Term: Multiple sclerosis
MedDRA version: 12.0;Classification code 10063399;Term: Relapsing-remitting multiple sclerosis
MedDRA version: 12.0;Classification code 10053395;Term: Progressive multiple sclerosis
Product Name: Trichuris suis Ova
Product Code: TSO
INN or Proposed INN: Trichuris suis eggs
Other descriptive name: Trichuris suis eggs
Danish Multiple Sclerosis Research CenterNULLNot RecruitingFemale: yes
Male: yes
10Denmark

46. Malignant rheumatoid arthritis    [ 4,183 clinical trials,   2,538 drugs,   (DrugBank: 401 drugs),   183 drug target genes,   219 drug target pathways]
Searched query = "Malignant rheumatoid arthritis", "Rheumatoid arthritis", "Rheumatoid arthritis with vasculitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 4,183 trial found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
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Status
Inclusion_
agemin
Inclusion_
agemax
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gender
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size
PhaseCountries
1EUCTR2011-006344-71-DE
(EUCTR)
08/02/201325/04/2012Treatment with eggs of pig whipworm for patients with rheumatoid arthritis, who are insufficiently treated with methotrexateTrichuris suis ova (TSO) as a additional therapy for rheumatoid arthritis patients with insufficient response to methotrexate. A prospective, double-blind, randomized, controlled monocenter study. Rheumatoid arthritis
MedDRA version: 14.1;Level: PT;Classification code 10039073;Term: Rheumatoid arthritis;System Organ Class: 10028395 - Musculoskeletal and connective tissue disorders;Therapeutic area: Diseases [C] - Musculoskeletal Diseases [C05]
Trade Name: Trichuris suis ova
Product Name: Trichuris suis ova
Product Code: TSO
INN or Proposed INN: Trichuris suis ova
Other descriptive name: Pig whipworm eggs
Immanuel Krankenhaus BerlinNULLNot RecruitingFemale: yes
Male: yes
50Phase 2Germany

97. Ulcerative colitis    [ 2,269 clinical trials,   1,331 drugs,   (DrugBank: 241 drugs),   114 drug target genes,   181 drug target pathways]
Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 2,269 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
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size
PhaseCountries
1NCT03565939
(ClinicalTrials.gov)
May 4, 201822/5/2018Probiotic Treatment of Ulcerative Colitis With Trichuris Suis Ova (TSO)Probiotic Treatment of Ulcerative Colitis With Trichuris Suis Ova (TSO)Ulcerative Colitis Chronic ModerateBiological: Trichuris suis ova;Biological: PlaceboParaTech A/SNULLRecruiting18 Years75 YearsAll120Phase 2Denmark
2EUCTR2017-004772-65-DK
(EUCTR)
05/02/201804/12/2017Probiotic Treatment of Ulcerative Colitis with Trichuris suis ova (TSO)Probiotic Treatment of Ulcerative Colitis with Trichuris suis ova (TSO) - PROCTO Ulcerative Colitis
MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856 ;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
ParaTech A/SNULLAuthorised-recruitment may be ongoing or finished Female: yes
Male: yes
120Phase 2Denmark
3NCT01953354
(ClinicalTrials.gov)
November 201324/9/2013Trichuris Suis Ova Treatment in Left-sided Ulcerative ColitisA Prospective, Randomized, Double-blind, Placebo-controlled Phase II Clinical Study of Trichuris Suis Ova Treatment in Left-sided Ulcerative Colitis and Its Effects on Mucosal Immune State and MicrobiotaColitis, UlcerativeBiological: Trichuris suis ova (TSO);Biological: PlaceboNational Institute of Allergy and Infectious Diseases (NIAID)Coronado Biosciences, Inc.;Autoimmunity Centers of ExcellenceTerminated18 Years70 YearsAll16Phase 2United States