Loperamide    (DrugBank: Loperamide)

2 diseases
IDDisease name (Link within this page)Number of trials
13Multiple sclerosis/Neuromyelitis optica1
97Ulcerative colitis3

13. Multiple sclerosis/Neuromyelitis optica    [ 3,050 clinical trials,   2,147 drugs,   (DrugBank: 348 drugs),   244 drug target genes,   228 drug target pathways]
Searched query = "Multiple sclerosis/Neuromyelitis optica", "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 3,050 trial found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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PhaseCountries
1NCT02217982
(ClinicalTrials.gov)
July 201430/7/2014Pilot Study to Assess Dimethyl Fumarate Related GI Symptom MitigationA Pilot Study to Assess Dimethyl Fumarate (Tecfidera) Related GI Symptom Mitigation Via Food Bolus Alteration and Simethicone/Loperamide AdministrationRelapsing Remitting Multiple SclerosisDrug: Simethicone;Drug: Loperamide;Other: Peanut ButterRocky Mountain MS Research Group, LLCBiogenTerminated18 YearsN/AAll5Phase 4United States

97. Ulcerative colitis    [ 2,269 clinical trials,   1,331 drugs,   (DrugBank: 241 drugs),   114 drug target genes,   181 drug target pathways]
Searched query = "Ulcerative colitis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 2,269 trials found
No.TrialIDDate_
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registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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agemin
Inclusion_
agemax
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gender
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size
PhaseCountries
1EUCTR2019-003220-21-GB
(EUCTR)
26/02/202012/12/2019Management of diarrhoea in ulcerative colitis: multi-arm multi stage trial of low FODMAP diet, amitriptyline, ondansetron, or loperamide: MODULATE.Management of diarrhoea in ulcerative colitis: multi-arm multi-stage trial of low FODMAP diet, amitriptyline, ondansetron, or loperamide: MODULATE. - MODULATE Diarrhoea in patients with stable ulcerative colitis.
MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative colitis;System Organ Class: 100000004856
MedDRA version: 20.1;Classification code 10033007;Term: Other ulcerative colitis;Classification code 10066557;Term: Chronic diarrhoea;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Trade Name: Amitriptyline
Product Name: Amitriptyline
INN or Proposed INN: Amitriptyline hydrochloride
Product Name: Ondansetron
INN or Proposed INN: Ondansetron hydrochloride dihydrate
Product Name: Loperamide
INN or Proposed INN: loperamide hydrochloride
University of LeedsNULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
491Phase 2;Phase 3United Kingdom
2EUCTR2014-004740-35-DK
(EUCTR)
19/12/201425/11/2014Loperamide vs. Placebo's effect on Ileostomy outputLoperamide vs. Placebo's effect on ileostomy output: A clincal randomized patientblinded crossover study Patients with ileostomy because of ulcerative colitis, rectal cancer or short bowel syndrom
MedDRA version: 17.1;Level: LLT;Classification code 10012727;Term: Diarrhea;System Organ Class: 100000004856;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Trade Name: Imolope
Product Name: Imolope
Product Code: A07DA03
INN or Proposed INN: LOPERAMIDE
Department of surgery, Odense University HospitalNULLNot RecruitingFemale: yes
Male: yes
Phase 4Denmark
3NCT02266849
(ClinicalTrials.gov)
October 20148/10/2014Loperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over StudyLoperamide vs. Placebo's Effect on Ileostomy Output: A Clinical Randomized Blinded Cross-over StudyRectal Cancer;Ulcerative Colitis;Short Bowel SyndromeDrug: Loperamide;Drug: PlaceboOdense University HospitalNULLTerminated18 YearsN/ABoth12Phase 3Denmark