DDrare: Database of Drug Development for Rare Diseases

Human neural stem cells (DrugBank: -)

2 diseases

ID	Disease name (Link within this page)	Number of trials
2	Amyotrophic lateral sclerosis	1
13	Multiple sclerosis/Neuromyelitis optica	1

2. Amyotrophic lateral sclerosis [ 508 clinical trials, 530 drugs, (DrugBank: 146 drugs), 170 drug target genes, 221 drug target pathways]

Searched query = "Amyotrophic lateral sclerosis", "ALS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 508 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01640067 (ClinicalTrials.gov)	December 2011	9/7/2012	Human Neural Stem Cell Transplantation in Amyotrophic Lateral Sclerosis (ALS)	Intra-spinal Cord Delivery of Human Neural Stem Cells in ALS Patients: Proposal for a Phase I Study/ Trapianto Intramidollare di Cellule Staminali Neurali Umane Come Terapia Putativa Per la SLA: Proposta di un Trial Clinico di Fase I	Amyotrophic Lateral Sclerosis	Biological: Human Neural Stem Cells	Azienda Ospedaliera Santa Maria, Terni, Italy	Azienda Ospedaliero Universitaria Maggiore della Carita;Università di Padova Italy	Completed	20 Years	75 Years	Both	18	Phase 1	Italy

13. Multiple sclerosis/Neuromyelitis optica [ 3,050 clinical trials, 2,147 drugs, (DrugBank: 348 drugs), 244 drug target genes, 228 drug target pathways]

Searched query = "Multiple sclerosis/Neuromyelitis optica", "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 3,050 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03282760 (ClinicalTrials.gov)	September 9, 2017	9/8/2017	Safety Study of Human Neural Stem Cells Injections for Secondary Progressive Multiple Sclerosis Patients	A Phase I Multicenter Study of Allogenic, Intracerebroventricular Human Neural Stem Cells Transplantation for the Experimental Treatment of Secondary Progressive Multiple Sclerosis Patients	Secondary-progressive Multiple Sclerosis	Biological: Human Neural Stem Cells	Casa Sollievo della Sofferenza IRCCS	Associazione Revert ONLUS;Neurocenter of Southern Switzerland;Fondazione Cellule Staminali	Active, not recruiting	18 Years	60 Years	All	24	Phase 1	Italy;Switzerland