DDrare: Database of Drug Development for Rare Diseases

Dapsone (DrugBank: Dapsone)

4 diseases

ID	Disease name (Link within this page)	Number of trials
35	Pemphigus	1
42	Polyarteritis nodosa	1
60	Aplastic anemia	1
84	Sarcoidosis	1

35. Pemphigus [ 87 clinical trials, 114 drugs, (DrugBank: 37 drugs), 17 drug target genes, 158 drug target pathways]

Searched query = "Pemphigus"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 87 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00429533 (ClinicalTrials.gov)	November 1996	29/1/2007	Efficacy of Dapsone as a Steroid Sparing Agent in Pemphigus Vulgaris	A Prospective Randomized Placebo-Controlled Clinical Trial of Dapsone as a Glucocorticoid-Sparing Agent in Maintenance Phase Pemphigus Vulgaris	Pemphigus Vulgaris	Drug: Dapsone	Jacobus Pharmaceutical	NULL	Terminated	18 Years	80 Years	Both	48	Phase 2	United States

42. Polyarteritis nodosa [ 14 clinical trials, 27 drugs, (DrugBank: 16 drugs), 26 drug target genes, 102 drug target pathways]

Searched query = "Polyarteritis nodosa", "PAN"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 14 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02939573 (ClinicalTrials.gov)	January 2017	18/10/2016	A Randomized Multicenter Study for Isolated Skin Vasculitis	A Randomized Multicenter Study for Isolated Skin Vasculitis	Primary Cutaneous Vasculitis;Cutaneous Polyarteritis Nodosa;IgA Vasculitis;Henoch-Schönlein Purpura	Drug: Colchicine;Drug: Dapsone;Drug: Azathioprine	University of Pennsylvania	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS);National Center for Advancing Translational Science (NCATS);Office of Rare Diseases (ORD)	Recruiting	18 Years	N/A	All	90	Phase 2	United States;Canada;Japan

60. Aplastic anemia [ 218 clinical trials, 362 drugs, (DrugBank: 81 drugs), 39 drug target genes, 155 drug target pathways]

Searched query = "Aplastic anemia"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 218 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00993694 (ClinicalTrials.gov)	January 2009	9/10/2009	Methemoglobinemia in Young Patients With Hematologic Cancer or Aplastic Anemia Treated With Dapsone	Dapsone Induced Methemoglobinemia in Pediatric Hematologic Malignancy and Aplastic Anemia	Chronic Myeloproliferative Disorders;Leukemia;Lymphoma;Lymphoproliferative Disorder;Methemoglobinemia;Multiple Myeloma and Plasma Cell Neoplasm;Myelodysplastic Syndromes;Myelodysplastic/Myeloproliferative Neoplasms;Nonmalignant Neoplasm	Drug: chemotherapy;Drug: dapsone;Other: medical chart review;Procedure: assessment of therapy complications	Vanderbilt University	National Cancer Institute (NCI)	Completed	N/A	18 Years	All	41	N/A	United States

84. Sarcoidosis [ 143 clinical trials, 221 drugs, (DrugBank: 79 drugs), 82 drug target genes, 165 drug target pathways]

Searched query = "Sarcoidosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 143 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00000596 (ClinicalTrials.gov)	June 1978	27/10/1999	Diffuse Fibrotic Lung Disease		Lung Diseases;Pulmonary Fibrosis;Sarcoidosis	Drug: prednisone;Drug: cyclophosphamide;Drug: dapsone	National Heart, Lung, and Blood Institute (NHLBI)	NULL	Completed	18 Years	N/A	Both		Phase 2	NULL