Amg 557    (DrugBank: -)

1 disease
IDDisease name (Link within this page)Number of trials
49Systemic lupus erythematosus3

49. Systemic lupus erythematosus    [ 827 clinical trials,   638 drugs,   (DrugBank: 168 drugs),   108 drug target genes,   191 drug target pathways]
Searched query = "Systemic lupus erythematosus", "SLE"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
3 / 827 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT01683695
(ClinicalTrials.gov)
June 201214/3/2012Safety Study of AMG 557 in Subjects With Lupus ArthritisA Randomized, Double-blind, Parallel, Placebo-controlled, Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Clinical Effect of AMG 557 in Systemic Lupus Erythematosus (SLE) Subjects With Active Lupus ArthritisLupus Arthritis, Systemic Lupus ErythematosusDrug: AMG 557;Drug: Matching PlaceboAmgenNULLCompleted18 Years65 YearsAll20Phase 1United States;Australia;Denmark;France;Germany;Malaysia;Taiwan;United Kingdom;Singapore
2NCT00774943
(ClinicalTrials.gov)
December 200816/10/2008A Study of AMG 557 in Adults With Systemic Lupus ErythematosusA Randomized, Double-blind, Placebo-controlled, Ascending, Multiple Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 557 in Subjects With Systemic Lupus ErythematosusSystemic Lupus ErythematosusDrug: AMG 557AmgenNULLCompleted18 Years70 YearsBoth58Phase 1United States;Canada
3NCT02391259
(ClinicalTrials.gov)
November 20066/1/2015A Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of AMG 557 in Subjects With Systemic Lupus ErythematosusRandomized, Multicenter, Double-Blind, Placebo-Controlled, Rising Single Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 557 in Subjects With Systemic Lupus ErythematosusSystemic Lupus ErythematosusDrug: AMG 557;Drug: PlaceboAmgenNULLCompleted18 Years70 YearsBoth57Phase 1United States;United Kingdom