DDrare: Database of Drug Development for Rare Diseases

Diltiazem (DrugBank: Diltiazem)

3 diseases

ID	Disease name (Link within this page)	Number of trials
51	Scleroderma	1
58	Hypertrophic cardiomyopathy	1
86	Pulmonary arterial hypertension	1

51. Scleroderma [ 466 clinical trials, 536 drugs, (DrugBank: 142 drugs), 110 drug target genes, 210 drug target pathways]

Searched query = "Scleroderma", "Systemic sclerosis", "SSc", "dcSSc", "lcSSc"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 466 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02801305 (ClinicalTrials.gov)	June 2016	9/6/2016	Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers	Assessing and Comparing the Effect of Diltiazem Gel Versus Nitroglycerin Ointment in Healing Process of Scleroderma Digital Ulcers.	Digital Ulcer of Scleroderma	Drug: Diltiazem Gel 2%;Drug: Nitroglycerin Ointment 2%;Drug: Vaseline	Mohammad Ali Nazarinia	Shiraz University of Medical Sciences	Completed	20 Years	70 Years	All	90	Phase 2	Iran, Islamic Republic of

58. Hypertrophic cardiomyopathy [ 92 clinical trials, 126 drugs, (DrugBank: 35 drugs), 40 drug target genes, 141 drug target pathways]

Searched query = "Hypertrophic cardiomyopathy"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 92 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00319982 (ClinicalTrials.gov)	January 2006	27/4/2006	Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem	Treatment of Preclinical Hypertrophic Cardiomyopathy With Diltiazem	Hypertrophic Cardiomyopathy	Drug: Diltiazem;Drug: Placebo	Brigham and Women's Hospital	National Heart, Lung, and Blood Institute (NHLBI);Boston Children’s Hospital	Completed	5 Years	39 Years	All	39	Phase 2;Phase 3	United States

86. Pulmonary arterial hypertension [ 1,083 clinical trials, 667 drugs, (DrugBank: 122 drugs), 98 drug target genes, 185 drug target pathways]

Searched query = "Pulmonary arterial hypertension", "PAH", "IPAH", "HPAH", "Eisenmenger syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 1,083 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01645826 (ClinicalTrials.gov)	July 2012	18/10/2011	Efficacy Study of Cardizem in Pulmonary Arterial Hypertension	Calcium Channel Blockers in Nitric Oxide Non-responder Pulmonary Arterial Hypertension.	Idiopathic Pulmonary Arterial Hypertension;Primary Pulmonary Hypertension;Pulmonary Arterial Hypertension;Familial Primary Pulmonary Hypertension	Drug: Diltiazem Hydrochloride;Drug: Sugar Pill	University of South Florida	NULL	Withdrawn	18 Years	N/A	All	0	N/A	United States