DDrare: Database of Drug Development for Rare Diseases

Methylphenidate, fluoxetin, risperidone (DrugBank: Methylphenidate, Fluoxetin, Risperidone)

7 diseases

ID	Disease name (Link within this page)	Number of trials
6	Parkinson disease	0
13	Multiple sclerosis/Neuromyelitis optica	0
34	Neurofibromatosis	0
84	Sarcoidosis	0
113	Muscular dystrophy	0
179	Williams syndrome	1
206	Fragile X syndrome	1

6. Parkinson disease [ 2,123 clinical trials, 2,046 drugs, (DrugBank: 324 drugs), 183 drug target genes, 198 drug target pathways]

Searched query = "Parkinson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,123 trial found

13. Multiple sclerosis/Neuromyelitis optica [ 3,050 clinical trials, 2,147 drugs, (DrugBank: 348 drugs), 244 drug target genes, 228 drug target pathways]

Searched query = "Multiple sclerosis/Neuromyelitis optica", "Multiple sclerosis", "Neuromyelitis optica", "MS", "NMOSD", "Devic disease", "Balo concentric sclerosis", "Baló concentric sclerosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 3,050 trial found

34. Neurofibromatosis [ 120 clinical trials, 182 drugs, (DrugBank: 72 drugs), 84 drug target genes, 194 drug target pathways]

Searched query = "Neurofibromatosis", "NF1", "von Recklinghausen disease", "NF2"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 120 trial found

84. Sarcoidosis [ 143 clinical trials, 221 drugs, (DrugBank: 79 drugs), 82 drug target genes, 165 drug target pathways]

Searched query = "Sarcoidosis"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 143 trial found

113. Muscular dystrophy [ 567 clinical trials, 442 drugs, (DrugBank: 93 drugs), 55 drug target genes, 151 drug target pathways]

Searched query = "Muscular dystrophy", "Dystrophinopathies", "Myotilinopathy", "Laminopathy", "Caveolinopathy", "LGMD1C", "Desminopathy", "Sarcoglycanopathy", "α-dystroglycanopathy", "FCMD", "Walker-Warburg syndrome", "Muscle-eye-brain disease", "Myotonic dystrophy", "Integrin α7 deficient CMD", "Rigid spine syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 567 trial found

179. Williams syndrome [ 4 clinical trials, 13 drugs, (DrugBank: 7 drugs), 8 drug target genes, 32 drug target pathways]

Searched query = "Williams syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 4 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00768820 (ClinicalTrials.gov)	May 2001	7/10/2008	The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome	The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome (VCFS), Williams Syndrome (WS)and Fragile X Syndrome Characterization, Treatment and Examining the Connection to Developmental and Molecular Factors	Velocardiofacial Syndrome;Williams Syndrome;Fragile X Syndrome	Drug: methylphenidate, fluoxetin, risperidone	The Chaim Sheba Medical Center	NULL	Recruiting	N/A	N/A	All	400	Phase 4	Israel

206. Fragile X syndrome [ 98 clinical trials, 73 drugs, (DrugBank: 27 drugs), 46 drug target genes, 57 drug target pathways]

Searched query = "Fragile X syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 98 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00768820 (ClinicalTrials.gov)	May 2001	7/10/2008	The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome	The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome (VCFS), Williams Syndrome (WS)and Fragile X Syndrome Characterization, Treatment and Examining the Connection to Developmental and Molecular Factors	Velocardiofacial Syndrome;Williams Syndrome;Fragile X Syndrome	Drug: methylphenidate, fluoxetin, risperidone	The Chaim Sheba Medical Center	NULL	Recruiting	N/A	N/A	All	400	Phase 4	Israel