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Dopamine agonists    (DrugBank: Dopamine)

3 diseases
IDDisease name (Link within this page)Number of trials
6Parkinson disease9
7Corticobasal degeneration0
74Prolactin secreting pituitary adenoma1

6. Parkinson disease    [ 2,123 clinical trials,   2,046 drugs,   (DrugBank: 324 drugs),   183 drug target genes,   198 drug target pathways]
Searched query = "Parkinson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
9 / 2,123 trials found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT04249544
(ClinicalTrials.gov)		December 3, 201928/1/2020Social Decision Making in Parkinson's DiseaseCognitive and Neural Mechanisms of Impaired Social Decision-Making in Parkinson's Patients Taking Dopamine AgonistsParkinson DiseaseDrug: Pramipexole;Drug: PlaceboVanderbilt University Medical CenterUnited States Department of DefenseRecruiting45 Years80 YearsAll60Phase 1United States
2NCT02347059
(ClinicalTrials.gov)		January 201520/1/2015L-dopa Versus Dopamine Agonists After Subthalamic Nucleus Deep Brain Stimulation in Parkinson's DiseaseA Randomized, Single-blind Trial on the Efficacy and Safety of L-dopa Monotherapy Versus Dopamine Agonists Monotherapy After Subthalamic Nucleus Deep Brain Stimulation in Parkinson's DiseaseParkinson's DiseaseDrug: L-dopa;Drug: Dopamine Agonists (pramipexole, ropirinole)University of TorontoMichael J. Fox Foundation for Parkinson's ResearchRecruitingN/AN/ABoth40Phase 2Canada
3NCT01007864
(ClinicalTrials.gov)		January 20103/11/2009Influence of Piribedil (Clarium®) on Vigilance and Cognitive Function in Patients With Parkinson's Disease Compared to Other Non-Ergot Dopamine AgonistsInfluence of the Non-Ergot Dopamine Agonist Piribedil on Vigilance and Cognitive Function in Patients With Parkinson's Disease Compared to Other Oral Non-Ergot Dopamine AgonistsIdiopathic Parkinson's DiseaseDrug: piribedil;Drug: pramipexole or ropiniroleDesitin Arzneimittel GmbHFGK Clinical Research GmbHCompleted35 Years80 YearsBoth80Phase 3Germany
4EUCTR2009-012419-16-DE
(EUCTR)		03/12/200920/10/2009Influence of the Non-Ergot Dopamine agonist Piribedil on vigilance and cognitive function in patients with Parkinson's disease compared to other oral Non-Ergot Dopamine agonists - PIVICOG-PDInfluence of the Non-Ergot Dopamine agonist Piribedil on vigilance and cognitive function in patients with Parkinson's disease compared to other oral Non-Ergot Dopamine agonists - PIVICOG-PD idiopathic Parkinson's disease
MedDRA version: 12.0;Level: PT;Classification code 10061536;Term: Parkinson's disease		Trade Name: Clarium 50 mg Retardtabletten
INN or Proposed INN: piribedil		Desitin Arzneimittel GmbHNULLNot RecruitingFemale: yes
Male: yes		Germany
5NCT01049984
(ClinicalTrials.gov)		December 200913/1/2010Rasagiline as Add on to Dopamine Agonists in the Treatment of Parkinson's DiseaseA Double-blind, Placebo Controlled, Randomized, Multicenter Study to Assess the Safety and Clinical Benefit of Rasagiline as an Add on Therapy to Stable Dose of Dopamine Agonists in the Treatment of Early Parkinson's DiseaseParkinson's DiseaseDrug: Rasagiline;Drug: PlaceboTeva Neuroscience, Inc.H. Lundbeck A/SCompleted30 YearsN/AAll328Phase 4United States
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
6EUCTR2009-015833-66-IT
(EUCTR)		20/01/200918/04/2012Ropinirole 24h prolonged release and motor fluctuations: a study to control the wearing-off induced by dopamine agonists immediate releaseRopinirole 24h prolonged release and motor fluctuations: a study to control the wearing-off induced by dopamine agonists immediate release Parkinson's Disease
MedDRA version: 14.1;Level: LLT;Classification code 10013113;Term: Disease Parkinson's;System Organ Class: 10029205 - Nervous system disorders;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]		Trade Name: REQUIP*28CPR 8MG R.P.
INN or Proposed INN: ROPINIROLE
Other descriptive name: NA
Trade Name: REQUIP*21CPR 5MG
INN or Proposed INN: ROPINIROLE
Other descriptive name: NA
Trade Name: MIRAPEXIN*30CPR 0,7MG
INN or Proposed INN: PRAMIPEXOLE
Other descriptive name: NA		CASA DI CURA PRIVATA S.RAFFAELE - PISANANULLNot RecruitingFemale: yes
Male: yes		Italy
7NCT00443872
(ClinicalTrials.gov)		March 20073/3/2007Efficacy of Orally Disintegrating Selegiline in Parkinson's Patients Experiencing Adverse Effects With Dopamine AgonistsAdding Orally Disintegrating Selegiline (Zelapar) to Patients Taking Dopamine Agonists and Experiencing ComplicationsParkinson's DiseaseDrug: orally disintegrating selegiline (Zelapar)Parkinson's Disease and Movement Disorder Center of Boca RatonValeant Pharmaceuticals International, Inc.Completed30 Years90 YearsAll77Phase 4United States
8NCT00465452
(ClinicalTrials.gov)		January 200724/4/2007Impact of Switching to Continuous Release Dopamine AgonistsThe Impact of Switching to Continuous Release Dopamine Agonists on Non-Motor Side EffectsParkinson DiseaseDrug: Continuous Release Dopamine AgonistsUniversity of Toledo Health Science CampusNULLCompleted55 YearsN/ABoth15Phase 3United States
9NCT02233023
(ClinicalTrials.gov)		June 19984/9/2014Ophthalmologic Safety of Long Term Treatment With Pramipexole Compared to Bromocriptine or Other Dopamine Agonists in Patients With Parkinson's DiseaseMatched Pair, Assessor Blinded, Open Label Clinical Trial to Assess the Ophthalmologic Safety of Long Term Oral Treatment With Pramipexole Compared to Bromocriptine or Other Dopamine Agonists in Patients With Parkinson's DiseaseParkinson DiseaseDrug: Pramipexole;Drug: Bromocriptine and other dopamine agonistsBoehringer IngelheimNULLCompletedN/AN/ABoth705Phase 4NULL

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7. Corticobasal degeneration    [ 16 clinical trials,   33 drugs,   (DrugBank: 11 drugs),   6 drug target genes,   13 drug target pathways]
Searched query = "Corticobasal degeneration", "Corticobasal syndrome", "CBD"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.
0 / 16 trial found

74. Prolactin secreting pituitary adenoma    [ 18 clinical trials,   33 drugs,   (DrugBank: 10 drugs),   16 drug target genes,   63 drug target pathways]
Searched query = "Prolactin secreting pituitary adenoma", "Pituitary PRL secretion hyperthyroidism", "Prolactinoma", "Prolactin secreting adenoma"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
1 / 18 trial found
No.TrialIDDate_
enrollment		Date_
registration		Public_titleScientific_titleConditionInterventionPrimary_
sponsor		Secondary_
sponsor		Recruitment_
Status		Inclusion_
agemin		Inclusion_
agemax		Inclusion_
gender		Target_
size		PhaseCountries
1NCT04107480
(ClinicalTrials.gov)		June 21, 201927/8/2019PRolaCT - Three Prolactinoma RCTsPRolaCT - Three Multicenter Prolactinoma Randomized Clinical TrialsProlactinoma;Prolactin-Producing Pituitary TumorProcedure: Endoscopic trans-sphenoidal adenoma resection;Drug: Dopamine AgonistsLeiden University Medical CenterNULLRecruiting18 YearsN/AAll880Phase 4Netherlands

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