Ak002    (DrugBank: -)

1 disease
IDDisease name (Link within this page)Number of trials
98Eosinophilic gastrointestinal disease6

98. Eosinophilic gastrointestinal disease    [ 128 clinical trials,   147 drugs,   (DrugBank: 40 drugs),   34 drug target genes,   132 drug target pathways]
Searched query = "Eosinophilic gastrointestinal disease", "Eosinophilic gastroenteritis", "Eosinophilic esophagitis", "Eosinophilic colitis", "Eosinophilic gastro-intestinal disorder", "EGID", "Neonatal food-protein induced enterocolitis", "N-FPIES"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.
6 / 128 trials found
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04620811
(ClinicalTrials.gov)
December 3, 20203/11/2020An Extension Study of Lirentelimab in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)A Phase 3, Multicenter, Open-Label, Extension Study to Evaluate the Efficacy and Safety of AK002 in Patients That Were Previously Enrolled in AK002-016 or AK002-012 Studies and Have Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)Eosinophilic Gastritis;Eosinophilic DuodenitisDrug: lirentelimabAllakos, Inc.NULLEnrolling by invitation18 Years80 YearsAll170Phase 3United States
2EUCTR2019-004391-19-NL
(EUCTR)
30/07/202013/05/2020Study to Evaluate the Efficacy and Safety of AK002 in Patients with Active Eosinophilic EsophagitisA Phase 2/3, Multicenter, Randomized, Double-Blind, Placebo Controlled Study to Evaluate the Efficacy and Safetyof AK002 in Adult and Adolescent Patients with Active Eosinophilic Esophagitis Active Eosinophilic Esophagitis (EoE)
MedDRA version: 20.0;Level: PT;Classification code 10064212;Term: Eosinophilic oesophagitis;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]
Product Name: Antolimab
Product Code: AK002
INN or Proposed INN: Antolimab
Allakos Inc.NULLAuthorised-recruitment may be ongoing or finishedFemale: yes
Male: yes
300Phase 2;Phase 3United States;Australia;Netherlands
3NCT04322708
(ClinicalTrials.gov)
July 6, 202024/3/2020A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic EsophagitisA Phase 2/3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Lirentelimab (AK002) in Adult and Adolescent Patients With Active Eosinophilic EsophagitisEosinophilic EsophagitisOther: Placebo;Drug: lirentelimab (AK002)Allakos, Inc.NULLRecruiting12 Years80 YearsAll300Phase 2;Phase 3United States;Australia;Netherlands
4NCT04322604
(ClinicalTrials.gov)
June 18, 202024/3/2020A Study to Assess AK002 in Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Efficacy and Safety of AK002 in Patients With Moderately to Severely Active Eosinophilic Gastritis and/or Eosinophilic Duodenitis (Formerly Referred to as Eosinophilic Gastroenteritis)Eosinophilic Gastritis;Eosinophilic DuodenitisDrug: lirentelimab (AK002);Other: PlaceboAllakos, Inc.NULLRecruiting18 Years80 YearsAll160Phase 3United States
5NCT03664960
(ClinicalTrials.gov)
November 14, 20186/9/2018An Extension Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic GastroenteritisA Phase 2, Multicenter, Open-Label, Extension Study to Evaluate the Safety and Tolerability of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic GastroenteritisEosinophilic Gastritis;Eosinophilic GastroenteritisDrug: AK002Allakos, Inc.NULLActive, not recruiting18 Years80 YearsAll58Phase 2United States
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
6NCT03496571
(ClinicalTrials.gov)
July 18, 20186/4/2018A Study of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic GastroenteritisA Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacodynamic Effect of AK002 in Patients With Eosinophilic Gastritis and/or Eosinophilic GastroenteritisEosinophilic Gastritis;Eosinophilic GastroenteritisDrug: AK002;Other: PlaceboAllakos, Inc.NULLCompleted18 Years80 YearsAll65Phase 2United States