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descriptions per page:
Showing 1 to 7 of 7 descriptions
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薬物名(臨床試験情報から抽出)
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
Combination Product: EGCG +
Nintedanib
2件:
Epigallocatechin gallate
Epigallocatechin gallate
,
Nintedanib
1件:
D10481
D10481
(Name:
Nintedanib
)
8件:
FGFR1
FGFR1
,
FGFR2
,
FGFR3
,
FLT1
,
FLT4
,
KDR
,
PDGFRA
,
PDGFRB
💬
34件:
Adherens junction
Adherens junction
,
Bladder cancer
,
Breast cancer
,
Calcium signaling pathway
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
EGFR tyrosine kinase inhibitor resistance
,
Endocytosis
,
Fluid shear stress and atherosclerosis
,
Focal adhesion
,
Gap junction
,
Gastric cancer
,
Glioma
,
HIF-1 signaling pathway
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
JAK-STAT signaling pathway
,
MAPK signaling pathway
,
Melanoma
,
MicroRNAs in cancer
,
PI3K-Akt signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Pathways in cancer
,
Phospholipase D signaling pathway
,
Prostate cancer
,
Proteoglycans in cancer
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Regulation of actin cytoskeleton
,
Rheumatoid arthritis
,
Signaling pathways regulating pluripotency of stem cells
,
Thermogenesis
,
Transcriptional misregulation in cancer
,
VEGF signaling pathway
💬
34件:
Adherens junction
,
Bladder cancer
,
Breast cancer
,
Calcium signaling pathway
,
Central carbon met
...
1件:
85
85
2
L01XE31 -
Nintedanib
1件:
Nintedanib
Nintedanib
1件:
D10481
D10481
(Name:
Nintedanib
)
8件:
FGFR1
FGFR1
,
FGFR2
,
FGFR3
,
FLT1
,
FLT4
,
KDR
,
PDGFRA
,
PDGFRB
💬
34件:
Adherens junction
Adherens junction
,
Bladder cancer
,
Breast cancer
,
Calcium signaling pathway
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
EGFR tyrosine kinase inhibitor resistance
,
Endocytosis
,
Fluid shear stress and atherosclerosis
,
Focal adhesion
,
Gap junction
,
Gastric cancer
,
Glioma
,
HIF-1 signaling pathway
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
JAK-STAT signaling pathway
,
MAPK signaling pathway
,
Melanoma
,
MicroRNAs in cancer
,
PI3K-Akt signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Pathways in cancer
,
Phospholipase D signaling pathway
,
Prostate cancer
,
Proteoglycans in cancer
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Regulation of actin cytoskeleton
,
Rheumatoid arthritis
,
Signaling pathways regulating pluripotency of stem cells
,
Thermogenesis
,
Transcriptional misregulation in cancer
,
VEGF signaling pathway
💬
34件:
Adherens junction
,
Bladder cancer
,
Breast cancer
,
Calcium signaling pathway
,
Central carbon met
...
1件:
85
85
3
NINTEDANIB
1件:
Nintedanib
Nintedanib
1件:
D10481
D10481
(Name:
Nintedanib
)
8件:
FGFR1
FGFR1
,
FGFR2
,
FGFR3
,
FLT1
,
FLT4
,
KDR
,
PDGFRA
,
PDGFRB
💬
34件:
Adherens junction
Adherens junction
,
Bladder cancer
,
Breast cancer
,
Calcium signaling pathway
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
EGFR tyrosine kinase inhibitor resistance
,
Endocytosis
,
Fluid shear stress and atherosclerosis
,
Focal adhesion
,
Gap junction
,
Gastric cancer
,
Glioma
,
HIF-1 signaling pathway
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
JAK-STAT signaling pathway
,
MAPK signaling pathway
,
Melanoma
,
MicroRNAs in cancer
,
PI3K-Akt signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Pathways in cancer
,
Phospholipase D signaling pathway
,
Prostate cancer
,
Proteoglycans in cancer
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Regulation of actin cytoskeleton
,
Rheumatoid arthritis
,
Signaling pathways regulating pluripotency of stem cells
,
Thermogenesis
,
Transcriptional misregulation in cancer
,
VEGF signaling pathway
💬
34件:
Adherens junction
,
Bladder cancer
,
Breast cancer
,
Calcium signaling pathway
,
Central carbon met
...
5件:
51
51
,
85
,
89
,
227
,
228
4
Nintedanib
150 mg and 100 mg soft capsules
1件:
Nintedanib
Nintedanib
1件:
D10481
D10481
(Name:
Nintedanib
)
8件:
FGFR1
FGFR1
,
FGFR2
,
FGFR3
,
FLT1
,
FLT4
,
KDR
,
PDGFRA
,
PDGFRB
💬
34件:
Adherens junction
Adherens junction
,
Bladder cancer
,
Breast cancer
,
Calcium signaling pathway
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
EGFR tyrosine kinase inhibitor resistance
,
Endocytosis
,
Fluid shear stress and atherosclerosis
,
Focal adhesion
,
Gap junction
,
Gastric cancer
,
Glioma
,
HIF-1 signaling pathway
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
JAK-STAT signaling pathway
,
MAPK signaling pathway
,
Melanoma
,
MicroRNAs in cancer
,
PI3K-Akt signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Pathways in cancer
,
Phospholipase D signaling pathway
,
Prostate cancer
,
Proteoglycans in cancer
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Regulation of actin cytoskeleton
,
Rheumatoid arthritis
,
Signaling pathways regulating pluripotency of stem cells
,
Thermogenesis
,
Transcriptional misregulation in cancer
,
VEGF signaling pathway
💬
34件:
Adherens junction
,
Bladder cancer
,
Breast cancer
,
Calcium signaling pathway
,
Central carbon met
...
1件:
227
227
5
Pirfenidone and
nintedanib
2件:
Nintedanib
Nintedanib
,
Pirfenidone
2件:
D01583
D01583
,
D10481
(Name:
Nintedanib
)
14件:
CCL2
CCL2
,
FGFR1
,
FGFR2
,
FGFR3
,
FLT1
,
FLT4
,
IL10
,
IL1A
,
IL1B
,
IL6
,
KDR
,
PDGFRA
,
PDGFRB
,
TNF
💬
106件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adherens junction
,
Adipocytokine signaling pathway
,
African trypanosomiasis
,
Alcoholic liver disease
,
Allograft rejection
,
Alzheimer disease
,
Amoebiasis
,
Amyotrophic lateral sclerosis
,
Antifolate resistance
,
Antigen processing and presentation
,
Apoptosis
,
Asthma
,
Autoimmune thyroid disease
,
Bladder cancer
,
Breast cancer
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Central carbon metabolism in cancer
,
Chagas disease
,
Chemokine signaling pathway
,
Choline metabolism in cancer
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Cytosolic DNA-sensing pathway
,
Dilated cardiomyopathy
,
EGFR tyrosine kinase inhibitor resistance
,
Endocytosis
,
Epstein-Barr virus infection
,
Fc epsilon RI signaling pathway
,
Fluid shear stress and atherosclerosis
,
Focal adhesion
,
FoxO signaling pathway
,
Gap junction
,
Gastric cancer
,
Glioma
,
Graft-versus-host disease
,
HIF-1 signaling pathway
,
Hematopoietic cell lineage
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Inflammatory mediator regulation of TRP channels
,
Influenza A
,
Insulin resistance
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
Measles
,
Melanoma
,
MicroRNAs in cancer
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
Osteoclast differentiation
,
PI3K-Akt signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Pathogenic Escherichia coli infection
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Phospholipase D signaling pathway
,
Prion disease
,
Prostate cancer
,
Proteoglycans in cancer
,
RIG-I-like receptor signaling pathway
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Regulation of actin cytoskeleton
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
Signaling pathways regulating pluripotency of stem cells
,
Sphingolipid signaling pathway
,
Staphylococcus aureus infection
,
Systemic lupus erythematosus
,
T cell receptor signaling pathway
,
TGF-beta signaling pathway
,
TNF signaling pathway
,
Th17 cell differentiation
,
Thermogenesis
,
Toll-like receptor signaling pathway
,
Toxoplasmosis
,
Transcriptional misregulation in cancer
,
Tuberculosis
,
Type I diabetes mellitus
,
Type II diabetes mellitus
,
VEGF signaling pathway
,
Viral protein interaction with cytokine and cytokine receptor
,
Yersinia infection
,
mTOR signaling pathway
💬
106件:
AGE-RAGE signaling pathway in diabetic complications
,
Adherens junction
,
Adipocytokine signali
...
1件:
85
85
6
Pirfenidone or
nintedanib
2件:
Nintedanib
Nintedanib
,
Pirfenidone
2件:
D01583
D01583
,
D10481
(Name:
Nintedanib
)
14件:
CCL2
CCL2
,
FGFR1
,
FGFR2
,
FGFR3
,
FLT1
,
FLT4
,
IL10
,
IL1A
,
IL1B
,
IL6
,
KDR
,
PDGFRA
,
PDGFRB
,
TNF
💬
106件:
AGE-RAGE signaling pathway in diabetic complications
AGE-RAGE signaling pathway in diabetic complications
,
Adherens junction
,
Adipocytokine signaling pathway
,
African trypanosomiasis
,
Alcoholic liver disease
,
Allograft rejection
,
Alzheimer disease
,
Amoebiasis
,
Amyotrophic lateral sclerosis
,
Antifolate resistance
,
Antigen processing and presentation
,
Apoptosis
,
Asthma
,
Autoimmune thyroid disease
,
Bladder cancer
,
Breast cancer
,
C-type lectin receptor signaling pathway
,
Calcium signaling pathway
,
Cellular senescence
,
Central carbon metabolism in cancer
,
Chagas disease
,
Chemokine signaling pathway
,
Choline metabolism in cancer
,
Coronavirus disease - COVID-19
,
Cytokine-cytokine receptor interaction
,
Cytosolic DNA-sensing pathway
,
Dilated cardiomyopathy
,
EGFR tyrosine kinase inhibitor resistance
,
Endocytosis
,
Epstein-Barr virus infection
,
Fc epsilon RI signaling pathway
,
Fluid shear stress and atherosclerosis
,
Focal adhesion
,
FoxO signaling pathway
,
Gap junction
,
Gastric cancer
,
Glioma
,
Graft-versus-host disease
,
HIF-1 signaling pathway
,
Hematopoietic cell lineage
,
Hepatitis B
,
Hepatitis C
,
Herpes simplex virus 1 infection
,
Human T-cell leukemia virus 1 infection
,
Human cytomegalovirus infection
,
Human immunodeficiency virus 1 infection
,
Human papillomavirus infection
,
Hypertrophic cardiomyopathy
,
IL-17 signaling pathway
,
Inflammatory bowel disease
,
Inflammatory mediator regulation of TRP channels
,
Influenza A
,
Insulin resistance
,
Intestinal immune network for IgA production
,
JAK-STAT signaling pathway
,
Kaposi sarcoma-associated herpesvirus infection
,
Legionellosis
,
Leishmaniasis
,
Lipid and atherosclerosis
,
MAPK signaling pathway
,
Malaria
,
Measles
,
Melanoma
,
MicroRNAs in cancer
,
NF-kappa B signaling pathway
,
NOD-like receptor signaling pathway
,
Natural killer cell mediated cytotoxicity
,
Necroptosis
,
Non-alcoholic fatty liver disease
,
Osteoclast differentiation
,
PI3K-Akt signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Pathogenic Escherichia coli infection
,
Pathways in cancer
,
Pathways of neurodegeneration - multiple diseases
,
Pertussis
,
Phospholipase D signaling pathway
,
Prion disease
,
Prostate cancer
,
Proteoglycans in cancer
,
RIG-I-like receptor signaling pathway
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Regulation of actin cytoskeleton
,
Rheumatoid arthritis
,
Salmonella infection
,
Shigellosis
,
Signaling pathways regulating pluripotency of stem cells
,
Sphingolipid signaling pathway
,
Staphylococcus aureus infection
,
Systemic lupus erythematosus
,
T cell receptor signaling pathway
,
TGF-beta signaling pathway
,
TNF signaling pathway
,
Th17 cell differentiation
,
Thermogenesis
,
Toll-like receptor signaling pathway
,
Toxoplasmosis
,
Transcriptional misregulation in cancer
,
Tuberculosis
,
Type I diabetes mellitus
,
Type II diabetes mellitus
,
VEGF signaling pathway
,
Viral protein interaction with cytokine and cytokine receptor
,
Yersinia infection
,
mTOR signaling pathway
💬
106件:
AGE-RAGE signaling pathway in diabetic complications
,
Adherens junction
,
Adipocytokine signali
...
1件:
85
85
7
Sub-Study:
Nintedanib
1件:
Nintedanib
Nintedanib
1件:
D10481
D10481
(Name:
Nintedanib
)
8件:
FGFR1
FGFR1
,
FGFR2
,
FGFR3
,
FLT1
,
FLT4
,
KDR
,
PDGFRA
,
PDGFRB
💬
34件:
Adherens junction
Adherens junction
,
Bladder cancer
,
Breast cancer
,
Calcium signaling pathway
,
Central carbon metabolism in cancer
,
Choline metabolism in cancer
,
EGFR tyrosine kinase inhibitor resistance
,
Endocytosis
,
Fluid shear stress and atherosclerosis
,
Focal adhesion
,
Gap junction
,
Gastric cancer
,
Glioma
,
HIF-1 signaling pathway
,
Human cytomegalovirus infection
,
Human papillomavirus infection
,
JAK-STAT signaling pathway
,
MAPK signaling pathway
,
Melanoma
,
MicroRNAs in cancer
,
PI3K-Akt signaling pathway
,
Parathyroid hormone synthesis, secretion and action
,
Pathways in cancer
,
Phospholipase D signaling pathway
,
Prostate cancer
,
Proteoglycans in cancer
,
Rap1 signaling pathway
,
Ras signaling pathway
,
Regulation of actin cytoskeleton
,
Rheumatoid arthritis
,
Signaling pathways regulating pluripotency of stem cells
,
Thermogenesis
,
Transcriptional misregulation in cancer
,
VEGF signaling pathway
💬
34件:
Adherens junction
,
Bladder cancer
,
Breast cancer
,
Calcium signaling pathway
,
Central carbon met
...
1件:
85
85