Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. DrugBank 薬物名（臨床試験情報から抽出） KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Ianalumab 1件: Ianalumab1件: D12151 1件: TNFRSF13C 💬5件: Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬5件: 35, 46, 49, 53, 95
2 Ibandronate 2件: Ibandronate; Ibandronic acid1件: D08056 1件: FDPS 💬4件: Human T-cell leukemia virus 1 infection, Influenza A, Metabolic pathways, Terpenoid backbone biosynthesis 💬3件: 46, 49, 274
3 Ibrutinib 1件: Ibrutinib1件: D10223 1件: BTK 💬7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬3件: 28, 60, 61
4 Ibudilast 1件: Ibudilast1件: D01385 8件: CYSLTR1,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PTGIR 💬		16件: Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 13
5 Ibuprofen 2件: Ibuprofen; IBUPROFEN 200MG4件: D00126 ,
D01122 ,
D04490 ,
D06606 		2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬7件: 13, 46, 65, 107, 113, 271, 299
6 Icosapent 2件: Eicosapentaenoic Acid; Icosapent1件: D08061 --11件: 8, 46, 48, 49, 96, 97, 113, 296, 297, 301, 338
7 Icosapent ethyl 2件: Ethyl-EPA; Icosapent1件: D01892 --2件: 8, 296
8 Icotinib 1件: Icotinib1件: D11251 1件: EGFR 💬48件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis 💬1件: 34
9 Idebenone 2件: Idebenone; Raxone1件: D01750 --6件: 6, 8, 13, 18, 113, 302
10 Idursulfase 4件: Elaprase; Iduronate 2-sulfatase; IDURSULFASA; IDURSULFASE1件: D04499 1件: IDS 💬3件: Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬1件: 19
11 Idursulfase beta 3件: Hunterase; Iduronate 2-sulfatase; Idursulfase beta1件: D11025 1件: IDS 💬3件: Glycosaminoglycan degradation, Lysosome, Metabolic pathways 💬1件: 19
12 Ifenprodil 1件: Ifenprodil1件: D08064 3件: ADRA1A,
ADRA1B,
ADRA1D 💬		7件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 85
13 Ifetroban 1件: Ifetroban1件: D04500 1件: TBXA2R 💬3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬3件: 51, 86, 113
14 Ifosfamide 1件: Ifosfamide1件: D00343 --1件: 34
15 Iguratimod 1件: Iguratimod1件: D01146 1件: NFKB1 💬76件: AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Antifolate resistance, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬4件: 46, 51, 53, 271
16 Iloprost 2件: Iloprost; Ventavis1件: D02721 1件: PTGIR 💬3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬4件: 51, 84, 85, 86
17 Imatinib 4件: Gleevec; GLIVEC; Imatinib; IMATINIB MESYLATE2件: D01441 ,
D08066 		3件: ABL1,
KIT,
PDGFRA 💬		32件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, EGFR tyrosine kinase inhibitor resistance, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162
18 Imidacloprid 0件: ---5件: 19, 20, 125, 234, 326
19 Imidapril 1件: Imidapril1件: D08068 1件: ACE 💬6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 67
20 Imiglucerase 3件: CEREZYME; IMIGLUCERASA; IMIGLUCERASE1件: D03020 1件: GBA 💬4件: Lysosome, Metabolic pathways, Other glycan degradation, Sphingolipid metabolism 💬1件: 19
21 Imipenem 1件: IMIPENEM2件: D00206 ,
D04515 		--1件: 60
22 Imiquimod 1件: Imiquimod1件: D02500 1件: TLR7 💬5件: Coronavirus disease - COVID-19, Influenza A, Measles, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway 💬2件: 34, 51
23 Imlifidase 2件: HMED-IdeS; IdeS1件: D11470 --2件: 64, 221
24 Implitapide 1件: Implitapide---1件: 79
25 Imrecoxib 1件: Imrecoxib---1件: 271
26 Inclisiran 2件: ALN-PCSSC; Inclisiran1件: D11931 1件: PCSK9 💬1件: Cholesterol metabolism 💬1件: 79
27 Indapamide 1件: Indapamide2件: D00345 ,
D06401 		1件: SLC12A3 💬-1件: 13
28 Indian frankincense 2件: Boswellia Serrata; Boswellia Serrata Extract---1件: 13
29 Indinavir 1件: Indinavir3件: D00897 ,
D02861 ,
D03833 		--1件: 265
30 Indium 1件: Indium---3件: 28, 84, 299
31 Indocyanine green 1件: Indocyanine green1件: D01342 --8件: 22, 46, 51, 96, 235, 278, 291, 296
32 Indole 1件: Indole---1件: 51
33 Indomethacin 2件: INDOMETACIN; Indomethacin3件: D00141 ,
D01565 ,
D02110 		2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298
34 Indopan 0件: ---4件: 8, 46, 97, 321
35 Inebilizumab 2件: INEBILIZUMAB; Uplizna1件: D11757 1件: CD19 💬5件: B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬4件: 11, 13, 51, 300
36 Infigratinib 1件: INFIGRATINIB1件: D11589 3件: FGFR1,
FGFR2,
FGFR3 💬		21件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, EGFR tyrosine kinase inhibitor resistance, Endocytosis, Gastric cancer, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Signaling pathways regulating pluripotency of stem cells, Thermogenesis 💬1件: 276
37 Infliximab 6件: Flixabi; Inflectra; Infliximab; Remicade; Remsima; Zessly1件: D02598 1件: TNF 💬67件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271
38 Influenza A virus A/Brisbane/59/2007 (H1N1) antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
39 Influenza A virus A/California/7/2009 (H1N1) live (attenuated) antigen 1件: FluMist---1件: 299
40 Influenza A virus A/California/7/2009 X-179A (H1N1) antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
41 Influenza A virus A/Perth/16/2009 (H3N2) live (attenuated) antigen 1件: FluMist---1件: 299
42 Influenza A virus A/South Dakota/6/2007 (H1N1) live (attenuated) antigen 1件: FluMist---1件: 299
43 Influenza A virus A/Switzerland/9715293/2013 NIB-88 (H3N2) antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
44 Influenza A virus A/Texas/50/2012 X-223A (H3N2) antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
45 Influenza A virus A/Uruguay/716/2007(H3N2) antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
46 Influenza A virus A/Uruguay/716/2007(H3N2) live (attenuated) antigen 1件: FluMist---1件: 299
47 Influenza A virus A/Victoria/210/2009 X-187 (H3N2) antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
48 Influenza A virus A/Victoria/361/2011 (H3N2) live (attenuated) antigen 1件: FluMist---1件: 299
49 Influenza A virus A/Victoria/361/2011 IVR-165 (H3N2) antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
50 Influenza B virus B/Brisbane/60/2008 antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
51 Influenza B virus B/Brisbane/60/2008 live (attenuated) antigen 1件: FluMist---1件: 299
52 Influenza B virus B/Massachusetts/2/2012 antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
53 Influenza B virus B/Massachusetts/2/2012 BX-51B antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
54 Influenza B virus B/Phuket/3073/2013 antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
55 Influenza B virus B/Texas/6/2011 antigen (formaldehyde inactivated) 1件: Fluzone---2件: 21, 49
56 Influenza B virus B/Wisconsin/1/2010 live (attenuated) antigen 1件: FluMist---1件: 299
57 Influenza virus type A (H1N1) 1件: FluMist---1件: 299
58 Influenza virus type A (H3N2) 1件: FluMist---1件: 299
59 Influenza virus type B 1件: FluMist---1件: 299
60 Inosine 1件: Inosine1件: D00054 --6件: 2, 6, 13, 17, 85, 122
61 Inositol 1件: Inositol1件: D08079 --2件: 96, 97
62 Inotersen 1件: INOTERSEN1件: D10940 1件: TTR 💬1件: Thyroid hormone synthesis 💬1件: 28
63 Insulin detemir 4件: Detemir; Insulin detemir; Levemir; Levemir Penfill1件: D04539 1件: INSR 💬22件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 299
64 Insulin glargine 1件: Insulin glargine1件: D03250 1件: INSR 💬22件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 299
65 Insulin human 1件: Human insulin2件: D00085 ,
D03230 		1件: INSR 💬22件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬2件: 96, 156
66 Insulin-like growth factor II 0件: ---1件: 19
67 Interferon alfa 1件: Interferon alfa1件: D03305 2件: IFNAR1,
IFNAR2 💬		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬6件: 13, 25, 26, 28, 56, 96
68 Interferon alfa-2a 3件: Interferon Alfa-2A; Interferon alpha-2a; Roferon-A1件: D00745 2件: IFNAR1,
IFNAR2 💬		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 56
69 Interferon alfa-2b 2件: Interferon alfa-2b; Interferon alpha-2B1件: D02745 2件: IFNAR1,
IFNAR2 💬		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬2件: 25, 34
70 Interferon beta-1a 6件: AVONEX; Interferon Beta 1-A; Interferon Beta 1a; Interferon beta-1a; Interferon-beta-1a; REBIF1件: D04554 2件: IFNAR1,
IFNAR2 💬		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬4件: 13, 26, 96, 97
71 Interferon beta-1b 7件: BETAFERON; Betaseron; EXTAVIA; Interferon beta 1B; INTERFERON BETA-1B; Interferon-beta-1b; RECOMBINANT INTERFERON BETA-1B1件: D00746 2件: IFNAR1,
IFNAR2 💬		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 13
72 Interferon Gamma 1件: Interferon Gamma---8件: 18, 65, 85, 107, 228, 299, 301, 326
73 Interferon gamma-1b 2件: ACTIMMUNE; Interferon gamma-1b1件: D00747 2件: IFNGR1,
IFNGR2 💬		18件: Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬7件: 18, 65, 85, 228, 299, 301, 326
74 Interleukin-1 alpha, human recombinant 1件: None---13件: 6, 46, 51, 65, 84, 85, 96, 97, 140, 161, 231, 271, 299
75 Interleukin-10 0件: ---1件: 46
76 Interleukin-7 2件: Interleukin-7; Recombinant human interleukin-7---1件: 25
77 Inulin 1件: Inulin1件: D00171 --2件: 96, 299
78 Iodide 1件: Iodide---1件: 34
79 Iodide I-123 2件: I 123; I-123---2件: 2, 6
80 Iodine 2件: Iodine; Iodo1件: D00108 --3件: 28, 46, 88
81 Ioflupane I-123 3件: DaTSCAN; Ioflupane; Ioflupane I 123---4件: 2, 5, 6, 17
82 Iohexol 2件: Iohexol; OMNIPAQUE1件: D01817 --3件: 19, 67, 222
83 Iopamidol 0件: 1件: D01797 --1件: 279
84 Ipilimumab 1件: Ipilimumab1件: D04603 1件: CTLA4 💬4件: Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬1件: 159
85 Ipratropium 1件: Ipratropium1件: D02212 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬		13件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬2件: 6, 86
86 Iproniazid 1件: IPRONIAZID1件: D02579 2件: MAOA,
MAOB 💬		14件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6
87 Iptacopan 1件: Iptacopan1件: D12251 1件: CFB 💬3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬5件: 61, 62, 66, 109, 222
88 IR208 0件: ---1件: 13
89 Irbesartan 2件: Aprovel; IRBESARTAN1件: D00523 1件: AGTR1 💬16件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬4件: 66, 167, 168, 222
90 Iron 1件: Iron---6件: 18, 96, 97, 238, 254, 284
91 Iron (III) oxide adipate 1件: Adipate---2件: 97, 228
92 Iron Dextran 1件: Iron Dextran1件: D02141 --4件: 62, 86, 96, 97
93 Iron polymaltose 1件: Fusion---9件: 11, 13, 46, 49, 69, 70, 86, 271, 299
94 Iron sucrose 1件: Iron Sucrose1件: D04616 --3件: 62, 96, 97
95 Isatuximab 1件: Isatuximab1件: D11050 1件: CD38 💬7件: Calcium signaling pathway, Hematopoietic cell lineage, Metabolic pathways, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬2件: 28, 61
96 Iscalimab 1件: ISCALIMAB1件: D11610 1件: CD40 💬17件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬2件: 49, 53
97 ISIS 104838 1件: ISIS 104838---1件: 46
98 Isoflurane 1件: Isoflurane1件: D00545 --1件: 6
99 Isoniazid 1件: Isoniazid3件: D00346 ,
D01501 ,
D02002 		--2件: 65, 254
100 Isosorbide 1件: Isosorbide1件: D00347 --1件: 113
101 Isosorbide dinitrate 2件: Isosorbide; ISOSORBIDE DINITRATE1件: D00516 --1件: 113
102 Isotretinoin 1件: Isotretinoin1件: D00348 2件: RARA,
RARB 💬		8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬4件: 36, 39, 159, 160
103 Isoxaflutole 1件: Balance---8件: 6, 11, 13, 81, 113, 122, 149, 299
104 Isoxsuprine 2件: Isoxsuprine; Isoxsuprine Hydrochloride1件: D08092 1件: ADRB2 💬9件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 13
105 Isradipine 1件: Isradipine1件: D00349 4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6
106 Istradefylline 1件: ISTRADEFYLLINE1件: D04641 1件: ADORA2A 💬7件: Alcoholism, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6
107 Itacitinib 1件: ITACITINIB1件: D10944 1件: JAK1 💬27件: Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬5件: 46, 51, 60, 97, 228
108 ITI-214 1件: ITI-214---1件: 6
109 Itolizumab 1件: Itolizumab---1件: 49
110 Itraconazole 2件: Itraconazole; Sporanox1件: D00350 --5件: 3, 65, 96, 227, 299
111 Ivacaftor 7件: IVACAFTOR; Kaftrio; Kalydeco; Orkambi; Symdeko; Symkevi; Trikafta1件: D09916 1件: CFTR 💬8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬1件: 299
112 Ixazomib 2件: Ixazomib; Ninlaro1件: D10130 1件: PSMB5 💬8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬5件: 13, 16, 28, 51, 61
113 Ixekizumab 2件: Ixekizumab; Taltz1件: D10071 1件: IL17A 💬6件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬6件: 36, 37, 107, 162, 269, 271