KEGG DRUG

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No.	KEGG DRUG	DrugBank	薬物名（臨床試験情報から抽出）	KEGG GENES	KEGG PATHWAY	指定難病告示番号
1	Acetylcysteine	1件: Acetylcysteine	3件: ACETYLCYSTEINE; Mucomyst; N-acetylcysteine;	-	-	20件: 6, 13, 19, 20, 34, 49, 51, 53, 58, 85, 90, 94, 111, 164, 193, 233, 296, 298, 299, 337
2	Valproic acid	1件: Valproic acid	3件: Valproate; VALPROATE SODIUM; Valproic Acid;	7件: ABAT, ALDH5A1, CACNA1G, CACNA1H, CACNA1I, GAD1, GAD2 💬	17件: Alanine, aspartate and glutamate metabolism, Aldosterone synthesis and secretion, Butanoate metabolism, Calcium signaling pathway, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, GABAergic synapse, GnRH secretion, MAPK signaling pathway, Metabolic pathways, Propanoate metabolism, Taurine and hypotaurine metabolism, Type I diabetes mellitus, Type II diabetes mellitus, Valine, leucine and isoleucine degradation, beta-Alanine metabolism 💬	17件: 2, 3, 5, 6, 13, 26, 34, 65, 85, 89, 90, 102, 127, 222, 233, 256, 331
3	Metformin hydrochloride	1件: Metformin	5件: Metformin; Metformin HCl; METFORMIN HYDROCHLORIDE; Metformina; Metformine;	2件: PRKAA1, PRKAA2 💬	20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬	24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
4	Dantrolene sodium	1件: Dantrolene	2件: Dantrolene; Dantrolene sodium;	-	-	2件: 13, 233
5	Dantrolene	1件: Dantrolene	2件: Dantrolene; Dantrolene sodium;	-	-	2件: 13, 233
6	Exenatide	1件: Exenatide	3件: BYDUREON; Byetta; EXENATIDE;	1件: GLP1R 💬	3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬	6件: 6, 17, 72, 78, 193, 233
7	Metformin	1件: Metformin	5件: Metformin; Metformin HCl; METFORMIN HYDROCHLORIDE; Metformina; Metformine;	2件: PRKAA1, PRKAA2 💬	20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬	24件: 2, 6, 8, 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301
8	Deferiprone	1件: Deferiprone	2件: Deferiprone; Ferriprox;	-	-	6件: 2, 6, 18, 120, 122, 233
9	Sitagliptin	1件: Sitagliptin	1件: Sitagliptin;	1件: DPP4 💬	1件: Protein digestion and absorption 💬	4件: 6, 75, 233, 299