Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Water 1件: Water9件: AVONEX; ENBREL; Glucagon; Hiberix; Indocyanine green; OMNITROPE; Sterile Water for Injection; Water; WATER FOR INJECTION; --23件: 2, 5, 6, 13, 17, 19, 22, 35, 46, 51, 53, 56, 57, 63, 65, 67, 78, 84, 96, 97, 226, 278, 299
2 Niacin 1件: Niacin2件: Niacin; Nicotinic acid; --4件: 6, 78, 79, 265
3 Testosterone 1件: Testosterone1件: Testosterone; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265
4 Hydrocortisone 1件: Hydrocortisone6件: Cortef; Cortisol; Cortisone; Hydrocortisone; Hydrocortisone cream; Hydrocortisonum; 1件: NR3C1 💬1件: Neuroactive ligand-receptor interaction 💬11件: 6, 41, 46, 53, 75, 78, 81, 83, 97, 98, 299
5 Gelatin 1件: Gelatin3件: Gelatin; Gelatine; Sulfur Colloid; --7件: 19, 28, 62, 78, 97, 269, 299
6 Glucagon 1件: Glucagon1件: Glucagon; 1件: GCGR 💬2件: Glucagon signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 78
7 Corticotropin 1件: Corticotropin5件: ACTH; Acthar; Adrenocorticotropic hormone; Corticotrophin; Corticotropin; 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬15件: 2, 13, 14, 46, 49, 50, 66, 75, 78, 81, 84, 145, 193, 205, 222
8 Clonidine 1件: Clonidine4件: Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE; 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 6, 65, 70, 78
9 Cosyntropin 1件: Tetracosactide4件: Cosyntropin; Synacthen Depot; Tetracosactide; Tetracosactrin; 1件: MC2R 💬5件: Aldosterone synthesis and secretion, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬5件: 78, 83, 113, 145, 222
10 Fluoxetine 1件: Fluoxetine5件: Fluoxetin; Fluoxetine; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬6件: 13, 17, 78, 86, 179, 206
11 Caffeine 1件: Caffeine1件: Caffeine; 11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
12 Clonidine hydrochloride 1件: Clonidine4件: Clonidin; Clonidina; Clonidine; CLONIDINE HYDROCHLORIDE; 3件: ADRA2A,
ADRA2B,
ADRA2C 💬		2件: Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬4件: 6, 65, 70, 78
13 Donepezil hydrochloride 1件: Donepezil3件: ARICEPT; Donepezil; Donepezil hydrochloride; 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
14 Amitriptyline hydrochloride 1件: Amitriptyline3件: Amitriptylin; Amitriptyline; Amitriptyline hydrochloride; 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 78, 97, 226, 299
15 Fluoxetine hydrochloride 1件: Fluoxetine5件: Fluoxetin; FLUOXETINE; FLUOXETINE HYDROCHLORIDE; Fluoxétine; PROZAC; 1件: SLC6A4 💬2件: Serotonergic synapse, Synaptic vesicle cycle 💬6件: 13, 17, 78, 86, 179, 206
16 Dextromethorphan hydrobromide 1件: Dextromethorphan4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta; 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
17 Diclofenac potassium 1件: Diclofenac3件: Diclofenac; Diclofenac Sodium; Diclofenac SR; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬5件: 13, 34, 46, 78, 271
18 Diclofenac sodium 1件: Diclofenac3件: Diclofenac; Diclofenac Sodium; Diclofenac SR; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬5件: 13, 34, 46, 78, 271
19 Pioglitazone hydrochloride 1件: Pioglitazone1件: Pioglitazone; 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
20 Testosterone cypionate 1件: Testosterone1件: Testosterone; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265
21 Testosterone enanthate 1件: Testosterone1件: Testosterone; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265
22 Testosterone propionate 1件: Testosterone1件: Testosterone; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265
23 Anastrozole 1件: Anastrozole2件: Anastrozole; Arimidex; 1件: CYP19A1 💬3件: Metabolic pathways, Ovarian steroidogenesis, Steroid hormone biosynthesis 💬3件: 78, 86, 193
24 Levothyroxine sodium 1件: Levothyroxine3件: Levothyroxine; Thyroid; Thyroxine; 2件: THRA,
THRB 💬		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬5件: 19, 49, 78, 80, 222
25 Liothyronine sodium 1件: Liothyronine4件: Liothyronine; Liothyronine sodium; Thyroid; Triiodothyronine; 2件: THRA,
THRB 💬		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬4件: 13, 78, 210, 212
26 Tramadol hydrochloride 1件: Tramadol2件: Tramadol; Ultracet; 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271
27 Caffeine hydrate 1件: Caffeine1件: Caffeine; 11件: ADORA1,
ADORA2A,
PDE1B,
PDE2A,
PDE3A,
PDE3B,
PDE4A,
PDE4B,
PDE4C,
PDE4D,
PDE5A 💬		22件: Alcoholism, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Metabolic pathways, Morphine addiction, Neuroactive ligand-receptor interaction, Olfactory transduction, Parathyroid hormone synthesis, secretion and action, Parkinson disease, Progesterone-mediated oocyte maturation, Purine metabolism, Rap1 signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Sphingolipid signaling pathway, Taste transduction, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬9件: 2, 6, 13, 21, 46, 78, 96, 97, 265
28 Sodium chloride 1件: Sodium chloride6件: Lactated Ringers; Natriumchlorid; REBIF; Saline; SODIUM CHLORIDE; Sporanox; --21件: 6, 11, 13, 14, 34, 46, 50, 51, 53, 60, 65, 67, 78, 96, 168, 193, 227, 228, 271, 288, 299
29 Glucagon hydrochloride 1件: Glucagon1件: Glucagon; 1件: GCGR 💬2件: Glucagon signaling pathway, Neuroactive ligand-receptor interaction 💬1件: 78
30 Somatropin 1件: Somatotropin17件: Genotropin; Growth hormone; Human growth hormone; Humatrope; Norditropin; Norditropin SimpleXx; NUTROPIN; Nutropin AQ; NutropinAq; OMNITROPE; Recombinant human growth hormone; RhGH; SAIZEN; Somatotropin; Somatropin; SOMATROPINA; Zomacton; 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬23件: 2, 3, 13, 19, 46, 65, 74, 75, 76, 78, 96, 107, 113, 187, 191, 193, 195, 236, 238, 265, 274, 276, 299
31 Albumin human 1件: Albumin human5件: Albumin; Human albumin; Human serum albumin; Optison; Serum albumin; --3件: 2, 78, 96
32 Arginine 1件: Arginine6件: Arginina; Arginine; L-Arg; L-Arginin; L-arginine; R-Gene; --12件: 46, 58, 65, 67, 78, 96, 97, 98, 113, 210, 251, 299
33 Mecasermin 1件: Mecasermin3件: Increlex; Mecasermin; MECASERMINA; 2件: GHR,
IGF1R 💬		33件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬6件: 65, 78, 96, 168, 265, 299
34 Polyethylene glycol 3350 1件: Polyethylene glycol4件: Macrogol; Macrogol 4000; Polyethylene glycol; Polyethylene Glycol 3350; --14件: 6, 13, 41, 46, 65, 78, 96, 97, 140, 144, 235, 240, 276, 299
35 Dextromethorphan 1件: Dextromethorphan4件: Dextromethorphan; DEXTROMETHORPHAN HYDROBROMIDE; Dextrometorfano; Nuedexta; 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
36 Dextromethorphan polistirex 1件: Dextromethorphan4件: Dextromethorphan; Dextromethorphan hydrobromide; Dextrometorfano; Nuedexta; 6件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D,
SIGMAR1 💬		20件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬11件: 2, 6, 8, 13, 21, 46, 78, 85, 96, 97, 156
37 Exenatide 1件: Exenatide3件: Bydureon; Byetta; Exenatide; 1件: GLP1R 💬3件: Insulin secretion, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬6件: 6, 17, 72, 78, 193, 233
38 Mecasermin rinfabate 1件: Mecasermin3件: Increlex; MECASERMIN; MECASERMINA; 2件: GHR,
IGF1R 💬		33件: AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway 💬6件: 65, 78, 96, 168, 265, 299
39 Pegvisomant 1件: Pegvisomant1件: Pegvisomant; 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
40 Human serum albumin 1件: Albumin human5件: Albumin; Human albumin; Human serum albumin; Optison; Serum albumin; --3件: 2, 78, 96
41 Testosterone ketolaurate 1件: Testosterone1件: Testosterone; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265
42 Testosterone undecanoate 1件: Testosterone1件: Testosterone; 1件: AR 💬4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬9件: 1, 2, 3, 13, 60, 76, 78, 113, 265
43 Tesamorelin 1件: Tesamorelin2件: GHRH; Tesamorelin; 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 78, 265
44 Donkey glue 1件: Gelatin3件: Gelatin; Gelatine; Sulfur Colloid; --7件: 19, 28, 62, 78, 97, 269, 299
45 Acipimox 1件: Acipimox1件: Acipimox; --2件: 78, 265
46 Tiratricol 1件: Tiratricol1件: TIRATRICOL; 2件: THRA,
THRB 💬		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬2件: 78, 139
47 Somatostatin 1件: Somatostatin1件: Somatostatin; 5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬		4件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬2件: 67, 78
48 Amitriptyline 1件: Amitriptyline3件: Amitriptylin; Amitriptyline; Amitriptyline hydrochloride; 2件: SLC6A2,
SLC6A4 💬		2件: Serotonergic synapse, Synaptic vesicle cycle 💬4件: 78, 97, 226, 299
49 Diclofenac 1件: Diclofenac3件: Diclofenac; Diclofenac Sodium; Diclofenac SR; 2件: PTGS1,
PTGS2 💬		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬5件: 13, 34, 46, 78, 271
50 Donepezil 1件: Donepezil3件: ARICEPT; DONEPEZIL; Donepezil hydrochloride; 1件: ACHE 💬2件: Cholinergic synapse, Glycerophospholipid metabolism 💬9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
51 Levothyroxine 1件: Levothyroxine3件: Levothyroxine; Thyroid; Thyroxine; 2件: THRA,
THRB 💬		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬5件: 19, 49, 78, 80, 222
52 Liothyronine 1件: Liothyronine4件: Liothyronine; Liothyronine sodium; Thyroid; Triiodothyronine; 2件: THRA,
THRB 💬		2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway 💬4件: 13, 78, 210, 212
53 Pioglitazone 1件: Pioglitazone1件: Pioglitazone; 1件: PPARG 💬11件: AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299
54 Strontium ranelate 1件: Strontium ranelate1件: Strontium ranelate; --1件: 78
55 Somatorelin 1件: Somatorelin2件: GHRH; Somatorelin; 1件: GHRHR 💬2件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction 💬2件: 13, 78
56 Tramadol 1件: Tramadol2件: Tramadol; Ultracet; 1件: OPRM1 💬3件: Estrogen signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction 💬5件: 46, 70, 78, 226, 271
57 Macimorelin 1件: Macimorelin2件: Macimorelin; Macrilen; 1件: GHSR 💬3件: Growth hormone synthesis, secretion and action, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 78
58 Somatrogon 1件: Somatrogon1件: Somatrogon; --1件: 78
59 Somavaratan 1件: Somavaratan1件: Somavaratan; 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
60 Somapacitan 1件: Somapacitan1件: SOMAPACITAN; 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78
61 Lonapegsomatropin 1件: Lonapegsomatropin1件: LONAPEGSOMATROPIN; 1件: GHR 💬5件: Cytokine-cytokine receptor interaction, Growth hormone synthesis, secretion and action, JAK-STAT signaling pathway, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway 💬1件: 78