Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 F2 8件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Platelet activation, Regulation of actin cytoskeleton, Pathogenic Escherichia coli infection, Coronavirus disease - COVID-19, Pathways in cancer D09707 Dabigatran 4件: 51, 85, 91, 124
2 ACHE 2件: Glycerophospholipid metabolism, Cholinergic synapse D00670 Donepezil 9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
3 ACHE 2件: Glycerophospholipid metabolism, Cholinergic synapse D07869 Donepezil 9件: 5, 6, 13, 46, 78, 124, 127, 156, 206
4 PDE3A 6件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction D01896 Cilostazol 3件: 51, 70, 124
5 PDE3B 11件: Purine metabolism, Metabolic pathways, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction D01896 Cilostazol 3件: 51, 70, 124
6 TBXA2R 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation D01896 Cilostazol 3件: 51, 70, 124
7 CALCA 2件: Neuroactive ligand-receptor interaction, Vascular smooth muscle contraction D11055 Fremanezumab 2件: 124, 226